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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 36 of 99

  1. DEB025

    ENANTA PHARMACEUTICALS INC

    Hepatitis C Virus

    phase 1 small molecule completed

    1 trial

  2. DEXTROMETHORPHANE ELERTE 1,5 mg/ml, sirop, AZD3470, AZD3470, Midazolam-ratiopharm® 2 mg/ml orale Lösung

    AstraZeneca AB

    Advanced/metastatic solid tumors that are MTAP deficient.

    phase 1 small molecule active

    1 trial

  3. DF-003

    BRIGHT MINDS BIOSCIENCES INC.

    ROSAH

    phase 1 small molecule active

    1 trial

  4. DFUPS

    United Therapeutics Europe Ltd

    Diabetic Foot

    phase 1 other completed

    1 trial

  5. DHAP

    Takeda

    Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  6. DIPHENHYDRAMINE, METHYLPREDNISOLONE, PARACETAMOL, ublituximab, Ublituximab, ublituximab, CETIRIZINE, DEXAMETHASONE

    TG THERAPEUTICS, INC.

    Relapsing multiple sclerosis, Myasthenia Gravis

    phase 1 small molecule active

    1 trial

  7. DISC-0974

    Disc Medicine

    Chronic Kidney Diseases

    phase 1 small molecule completed

    1 trial

  8. DISC-0974

    Disc Medicine

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  9. DISC-3405

    Disc Medicine

    Sickle Cell Disease

    phase 1 small molecule active

    1 trial

  10. DISC-3405

    Disc Medicine

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  11. DITEST

    NEUROCRINE BIOSCIENCES INC

    Male Hypogonadism

    phase 1 small molecule completed

    1 trial

  12. DM199

    DiaMedica Therapeutics

    Chronic Kidney Disease

    phase 1 small molecule completed

    1 trial

  13. DMPA

    United Therapeutics Europe Ltd

    Contraception

    phase 1 small molecule completed

    1 trial

  14. DMT in healthy subjects

    Lacuna Pharma Pty Ltd

    Stroke

    phase 1 other active

    1 trial

  15. DNL151

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  16. DNL201

    Denali Therapeutics

    Parkinson Disease

    phase 1 small molecule completed

    1 trial

  17. DNL201

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  18. DNL343

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  19. DNL628

    Denali Therapeutics

    Alzheimer Disease, Early Onset

    phase 1 small molecule active

    1 trial

  20. DNL747

    Denali Therapeutics

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  21. DNL747

    Denali Therapeutics

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule terminated

    1 trial

  22. DNL919

    Denali Therapeutics

    Healthy Participant

    phase 1 small molecule completed

    1 trial

  23. DNL952

    Denali Therapeutics

    Late-onset Pompe Disease

    phase 1 small molecule active

    1 trial

  24. DOSE-FINDING CLINICAL TRIAL TO EVALUATE OF INTESTINAL LACTASE ACTIVITY VIA ORAL GAXILOSE ADMINISTRATION IN HEALTHY ADULT VOLUNTEERS

    Lacuna Pharma Pty Ltd

    Hypolactasia

    phase 1 other active

    1 trial

  25. DP CD8 TIL

    Phio Pharmaceuticals

    HNSCC

    phase 1 mab active

    1 trial

  26. DS-1205c

    Daiichi Sankyo

    Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule terminated

    1 trial

  27. DSM265

    United Therapeutics Europe Ltd

    Healthy

    phase 1 small molecule completed

    1 trial

  28. DSP loaded RBC using EryDex System

    Quince Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  29. DT-216

    Lxo Ireland Designated Activity Company

    Friedreich Ataxia

    phase 1 small molecule completed

    2 trials

  30. DT2216

    United Therapeutics Europe Ltd

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  31. Dabigatran

    BRIGHT MINDS BIOSCIENCES INC.

    Mild Cognitive Impairment

    phase 1 small molecule terminated

    1 trial

  32. Dabigatran Etexilate

    CORCEPT THERAPEUTICS INC

    Cushing Syndrome

    phase 1 small molecule completed

    1 trial

  33. Danavorexton

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  34. Danicopan

    Alexion Europe SAS

    Healthy

    phase 1 small molecule completed

    1 trial

  35. Daprodustat 2 mg tablet

    GlaxoSmithKline

    Anaemia

    phase 1 small molecule completed

    1 trial

  36. Daratumumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Aplastic Anemia

    phase 1 small molecule completed

    1 trial

  37. Daratumumab

    Takeda

    Newly Diagnosed Primary Amyloidosis

    phase 1 mab active

    1 trial

  38. Daridorexant

    Jian Li

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  39. Darlifarnib

    Kura Oncology

    Solid Tumors With HRAS Alterations

    phase 1 small molecule active

    1 trial

  40. Dasatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed AML

    phase 1 small molecule terminated

    1 trial

  41. Dasatinib

    United Therapeutics Europe Ltd

    Malignant Pleural Mesothelioma

    phase 1 small molecule completed

    1 trial

  42. Daunorubicin

    Protara Therapeutics

    Acute Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  43. Dazucorilant

    CORCEPT THERAPEUTICS INC

    Healthy Adults

    phase 1 small molecule completed

    1 trial

  44. Dazucorilant

    CORCEPT THERAPEUTICS INC

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  45. Debio 0123 in combination with carboplatin and etoposide in adult participants with small cell lung cancer that recurred or progressed after platinum-based therapy.

    Alphapharm Pty Ltd

    Small cell lung cancer

    phase 1 other active

    1 trial

  46. Debio 0123, Debio 0123, Debio 0123, Debio 2513, Debio 0123, Debio 2513, Debio 0123, Debio 0123

    Alphapharm Pty Ltd

    Advanced solid tumors with CCNE1 amplification or deleterious mutations in FBXW7 or other proprietary gene

    phase 1 small molecule active

    1 trial

  47. Decision Aid

    United Therapeutics Europe Ltd

    Chronic Kidney Failure

    phase 1 other completed

    1 trial

  48. Decitabine

    Foghorn Therapeutics

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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