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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 98 of 99

  1. salvianolic acid A

    The First People's Hospital of Lianyungang

    Diabetes

    phase 1 small molecule active

    1 trial

  2. sapropterin dihydrochloride (6R-BH4)

    BioMarin Pharmaceutical Australia Pty Ltd

    Pulmonary Arterial Hypertension

    phase 1 small molecule completed

    1 trial

  3. sarilumab SAR153191 (REGN88)

    Sanofi Pasteur

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  4. selinexor

    Karyopharm Therapeutics Inc

    Recurrent Melanoma

    phase 1 small molecule completed

    1 trial

  5. selinexor

    Karyopharm Therapeutics Inc

    B-cell Lymphoma

    phase 1 small molecule completed

    1 trial

  6. selonabant

    Anebulo Pharmaceuticals

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  7. sevasemten

    Edgewise Therapeutics

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  8. shenhuang granule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sepsis

    phase 1 small molecule active

    1 trial

  9. sotagliflozin

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule active

    1 trial

  10. sotagliflozin

    LEXICON PHARMACEUTICALS, INC.

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  11. sparsentan

    Travere Therapeutics

    Proteinuric Renal Disease

    phase 1 small molecule active

    1 trial

  12. sphingosine kinase-2 inhibitor ABC294640

    Apogee Therapeutics

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  13. standard care

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 1 other terminated

    1 trial

  14. standard chemotherapy medicine combined with Chinese herbs

    The First People's Hospital of Lianyungang

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule active

    1 trial

  15. standard dose capecitabine

    Karyopharm Therapeutics Inc

    Rectal Neoplasms

    phase 1 small molecule active

    1 trial

  16. stem cells

    The First People's Hospital of Lianyungang

    Diminished Ovarian Response

    phase 1 other active

    1 trial

  17. sulfamethoxazole + MMX placebo

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  18. sulopenem etzadroxil and probenecid

    Iterum Therapeutics plc

    Pharmacokinetics After Oral Intake

    phase 1 small molecule active

    1 trial

  19. suramin sodium

    The First People's Hospital of Lianyungang

    Hand, Foot and Mouth Disease

    phase 1 small molecule active

    1 trial

  20. tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy

    phase 1 small molecule completed

    1 trial

  21. tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Circadian Rhythm Sleep Disorders

    phase 1 small molecule completed

    1 trial

  22. tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  23. tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Pharmacodyamics and Pharmacokinetics of Tasimelteon Alone and in Combination With Ethanol

    phase 1 small molecule completed

    1 trial

  24. teduglutide

    Takeda

    Pharmacokinetics and Safety of Elevated Doses

    phase 1 small molecule completed

    1 trial

  25. telaprevir (VX-950)

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatic Insufficiency

    phase 1 small molecule completed

    1 trial

  26. telaprevir formulation A

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  27. telavancin

    CUMBERLAND PHARMACEUTICALS INC

    Kidney Diseases

    phase 1 small molecule completed

    1 trial

  28. tirofiban in PV

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Coronary Artery Disease

    phase 1 small molecule active

    1 trial

  29. tofacitinib 10 mg

    Pfizer

    Healthy

    phase 1 small molecule completed

    1 trial

  30. tradipitant

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  31. transcutaneous auricular vagus nerve stimulation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy Participants

    phase 1 other active

    1 trial

  32. trastuzumab [Herceptin]

    Hoffmann-La Roche

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  33. treatment A

    United Therapeutics Europe Ltd

    Dyslipidemia

    phase 1 small molecule active

    1 trial

  34. treprostinil diethanolamine

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 1 small molecule completed

    2 trials

  35. triple-branched stent graft

    The First People's Hospital of Lianyungang

    Acute Aortic Dissection

    phase 1 other active

    1 trial

  36. uCD7 CART

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Myeloid Leukemia (AML)

    phase 1 mab active

    1 trial

  37. ucMSCs

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Bronchopulmonary Dysplasia

    phase 1 mab active

    1 trial

  38. universal CLL1 CAR-T cells

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  39. vadadustat

    Akebia Europe Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  40. vadadustat reference tablets

    Akebia Europe Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  41. veliparib

    BRIGHT MINDS BIOSCIENCES INC.

    Small Cell Lung Cancer SCLC

    phase 1 small molecule active

    1 trial

  42. vitamin D3

    S.L

    X-linked Adrenoleukodystrophy

    phase 1 other completed

    1 trial

  43. von Willebrand factor

    Ultragenyx UK Limited

    Von Willebrand's Disease

    phase 1 small molecule completed

    1 trial

  44. warfarin sodium

    IONIS PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  45. yimitasvir

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Hepatitis c

    phase 1 small molecule completed

    1 trial

  46. zanzalintinib

    Arcus Biosciences

    Advanced Clear Cell Renal Cell Carcinoma or Other Advanced Solid Tumors

    phase 1 small molecule terminated

    1 trial

  47. zelenirstat

    United Therapeutics Europe Ltd

    Relapsed Adult AML

    phase 1 small molecule active

    1 trial

  48. zelicapavir (therapeutic dose)

    ENANTA PHARMACEUTICALS INC

    RSV Infection

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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