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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. CXD101

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  2. CY-219 CAR-T

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory B-cell Lymphoma

    phase 1 small molecule active

    1 trial

  3. Cabiralizumab

    Prime Medicine

    Advanced Solid Tumors

    phase 1 mab completed

    1 trial

  4. Cabozantinib Oral Tablet

    United Therapeutics Europe Ltd

    Neurofibromatosis 1

    phase 1 small molecule active

    1 trial

  5. Calcichew D3

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  6. Calcitriol

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Calcium 500 mg and Vitamin D3 800 IU

    Takeda

    Calcium Deficiency

    phase 1 small molecule completed

    1 trial

  8. Cam2020 M2SR H3N2 influenza vaccine

    United Therapeutics Europe Ltd

    Influenza Vaccine

    phase 1 mab completed

    1 trial

  9. Camel milk containing Bifidobacterium animalis A6

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes

    phase 1 other completed

    1 trial

  10. Camidanlumab tesirine

    ADC Therapeutics SA

    Hodgkin Lymphoma

    phase 1 small molecule completed

    1 trial

  11. Campylobacter jejuni strain CG8421

    United Therapeutics Europe Ltd

    Campylobacter Infections

    phase 1 mab active

    1 trial

  12. Camrelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pancreatic Cancer

    phase 1 small molecule active

    1 trial

  13. Camsirubicin

    Monopar Therapeutics

    Advanced Soft-tissue Sarcoma

    phase 1 small molecule terminated

    1 trial

  14. Canagliflozin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Colorectal Cancer

    phase 1 small molecule active

    1 trial

  15. Cannabidiol, Medium Dose

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 1 small molecule active

    1 trial

  16. Cannabis

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Intoxication

    phase 1 small molecule active

    2 trials

  17. Cannabis

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule active

    2 trials

  18. Cannabis Cigarette

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use

    phase 1 small molecule completed

    1 trial

  19. Cannabis sativa Extract

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 1 small molecule active

    1 trial

  20. Capivasertib

    AstraZeneca

    Advanced Solid Tumours

    phase 1 small molecule completed

    1 trial

  21. Carbamazepine

    Aligos Therapeutics

    Healthy Volunteer

    phase 1 small molecule active

    1 trial

  22. Carbidopa

    United Therapeutics Europe Ltd

    Multiple Sclerosis

    phase 1 small molecule completed

    1 trial

  23. Carbon Monoxide inhalation

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 1 small molecule terminated

    1 trial

  24. Cardiac Resynchronization Therapy

    Rhythm Pharmaceuticals Netherlands B.V.

    Heart Failure

    phase 1 other completed

    1 trial

  25. Cardiac safety of treosulfan chemotherapy prior to stem cell transplantation in patients with leukemia.

    Medac Gesellschaft fuer klinische Spezialpraeparate mbH

    Subjects with AML ( Acute myeloid leukaemia) or MDS (Myelodysplastic syndrome) undergoing allogeneic hematopoietic stem cell transplantation

    phase 1 other active

    1 trial

  26. Cardiovascular safety assessment of Tanimilast in healthy volunteers

    Chiesi Farmaceutici S.p.A

    This is Phase I study to assess the effect on the heart rate (HR) and cardiovascular safety according to electrocardiographic monitoring (including QT and QTc intervals) of CHF6001(Tanimilast) administered with NEXThaler® device in healthy adult volunteers.

    phase 1 other active

    1 trial

  27. Carfilzomib

    ONCOLYTICS BIOTECH INC

    Recurrent Plasma Cell Myeloma

    phase 1 small molecule completed

    1 trial

  28. Carfilzomib

    Lxo Ireland Designated Activity Company

    Acute Lymphoblastic Leukemia (ALL)

    phase 1 small molecule completed

    1 trial

  29. Carmustine

    ADC Therapeutics SA

    Recurrent Diffuse Large B-Cell Lymphoma

    phase 1 small molecule terminated

    1 trial

  30. Carvedilol 25 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  31. Casdatifan

    Arcus Biosciences

    Healthy Participants

    phase 1 small molecule completed

    3 trials

  32. Casirivimab and Imdevimab Antibody Cocktail

    Regeneron UK Limited

    COVID-19

    phase 1 small molecule terminated

    1 trial

  33. Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03)

    Shanghai Reinovax Biologics Co.,LTD

    Idiopathic Pulmonary Fibrosis

    phase 1 small molecule completed

    1 trial

  34. Cefadroxil 500 mg Capsules

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  35. Cefdinir Capsules 300 mg

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  36. Cefdinir for oral suspension 250 mg/5mL

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  37. Cefprozil for oral suspension 250 mg/5 mL

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  38. Ceftobiprole OATP1B interaction study

    Lacuna Pharma Pty Ltd

    Community-acquired bacterial pneumonia

    phase 1 other active

    1 trial

  39. Cefzil® 500 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  40. Celecoxib

    Akebia Europe Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  41. Cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Periodontal Pocket

    phase 1 other active

    1 trial

  42. Cell therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary Ovarian Insufficiency

    phase 1 gene therapy active

    1 trial

  43. Cemiplimab

    Regeneron UK Limited

    Epithelial Ovarian Cancer

    phase 1 small molecule active

    1 trial

  44. Cemiplimab

    Regeneron UK Limited

    Hormone Receptor-positive Breast Cancer

    phase 1 small molecule completed

    1 trial

  45. Cemiplimab

    Regeneron UK Limited

    Lung Cancer

    phase 1 small molecule active

    1 trial

  46. Cemiplimab

    Regeneron UK Limited

    Locally Advanced Head and Neck Squamous Cell Carcinoma

    phase 1 small molecule active

    1 trial

  47. Cemiplimab

    Regeneron UK Limited

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  48. Cemiplimab

    Regeneron UK Limited

    Advanced Malignancies

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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