Monday, July 20, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 135
Sponsors 800
Drugs 4,222

Quick answer

NovaPharmaNews tracks 135 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 1 of 3

  1. 111-205

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 2 small molecule active

    1 trial

  2. 111-208

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 2 small molecule active

    1 trial

  3. 111-212

    BioMarin Pharmaceutical Australia Pty Ltd

    Hypochondroplasia

    phase 2 small molecule active

    1 trial

  4. 413ABM

    BRIGHT MINDS BIOSCIENCES INC.

    MALARIA

    phase 2 other completed

    1 trial

  5. 68Ga-FAP-CHX

    The First People's Hospital of Lianyungang

    Tumor

    phase 2 small molecule active

    1 trial

  6. ACP-103

    Acadia Pharmaceuticals B.V.

    Schizophrenia

    phase 2 small molecule completed

    1 trial

  7. AKB-6548

    Akebia Europe Limited

    Anemia

    phase 2 small molecule completed

    4 trials

  8. ALXN2420-Acro-201

    Alexion Europe SAS

    Acromegaly

    phase 2 small molecule active

    1 trial

  9. AMX0035

    Amylyx Pharmaceuticals EMEA B.V.

    ALS

    phase 2 small molecule active

    1 trial

  10. ARO-INHBE

    Arrowhead Pharmaceuticals Ireland Limited

    Obesity

    phase 2 small molecule active

    1 trial

  11. ARQ-252 cream 0.3%

    Arcutis Biotherapeutics

    Vitiligo

    phase 2 small molecule terminated

    1 trial

  12. ATI-50002 topical solution

    Aclaris Therapeutics

    Vitiligo

    phase 2 small molecule completed

    1 trial

  13. Active drug: pimavanserin 17mg (2 strength tablets)

    Acadia Pharmaceuticals B.V.

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  14. Apatinib

    The First People's Hospital of Lianyungang

    Thyroid

    phase 2 small molecule active

    1 trial

  15. Ataluren

    PTC THERAPEUTICS, INC.

    Aniridia

    phase 2 small molecule terminated

    2 trials

  16. Atorvastatin

    Hospital Authority, Hong Kong

    Vitiligo

    phase 2 small molecule completed

    1 trial

  17. Autologous Fat Transfer

    United Therapeutics Europe Ltd

    Wound

    phase 2 other completed

    1 trial

  18. BC45538

    Hoffmann-La Roche

    Obesity

    phase 2 small molecule active

    1 trial

  19. Bendamustine

    Adaptive Biotechnologies Corp

    Lymphoma

    phase 2 small molecule active

    1 trial

  20. Bevacizumab/Irinotecan

    Solid Biosciences

    Glioblastoma

    phase 2 small molecule completed

    1 trial

  21. CAN-201 NDG

    Lacuna Pharma Pty Ltd

    Glioblastoma

    phase 2 other active

    1 trial

  22. CTP-VLP-002

    CanSino Biologics

    Poliomyelitis

    phase 2 mab active

    1 trial

  23. Calcium Gluconate

    United Therapeutics Europe Ltd

    Trauma

    phase 2 small molecule active

    1 trial

  24. Carbon Nanoparticle Iron Suspension for Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HNSCC

    phase 2 small molecule active

    1 trial

  25. Clarithromycin

    Takeda

    Myeloma

    phase 2 small molecule active

    1 trial

  26. Cold Stored Platelets (CSP)

    United Therapeutics Europe Ltd

    Trauma

    phase 2 mab completed

    1 trial

  27. Cytarabine

    Hospital Authority, Hong Kong

    AML

    phase 2 small molecule active

    1 trial

  28. Cytarabine (Phase 1 only)

    Actinium Pharmaceuticals

    AML

    phase 2 small molecule completed

    1 trial

  29. DNA vaccine prime

    United Therapeutics Europe Ltd

    Malaria

    phase 2 mab completed

    1 trial

  30. Decitabine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    AML

    phase 2 small molecule terminated

    1 trial

  31. Defibrotide

    Jazz Pharmaceuticals Ireland Limited

    DLBCL

    phase 2 small molecule terminated

    1 trial

  32. Dexamethasone

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    ITP

    phase 2 small molecule active

    1 trial

  33. Dinutuximab

    United Therapeutics Europe Ltd

    Ganglioneuroblastoma

    phase 2 mab completed

    1 trial

  34. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioblastoma

    phase 2 small molecule terminated

    1 trial

  35. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioma

    phase 2 small molecule terminated

    1 trial

  36. E7090

    Eisai Co.,

    Cholangiocarcinoma

    phase 2 small molecule completed

    1 trial

  37. EP-005

    Lacuna Pharma Pty Ltd

    Obesity

    phase 2 small molecule active

    1 trial

  38. ETC-1002

    Esperion Therapeutics

    Dyslipidemia

    phase 2 small molecule completed

    1 trial

  39. Fibromun, Temozolomide SUN 100 mg hard capsules

    Philogen S.p.A.

    Glioblastoma

    phase 2 small molecule active

    1 trial

  40. Fremanezumab

    Teva Pharma GmbH

    Fibromyalgia

    phase 2 small molecule terminated

    1 trial

  41. GHR-LRX

    IONIS PHARMACEUTICALS INC

    Acromegaly

    phase 2 small molecule completed

    1 trial

  42. GLPG3667

    Lakefront Biotherapeutics NV

    Dermatomyositis

    phase 2 small molecule completed

    1 trial

  43. GWP42003-P

    Jazz Pharmaceuticals Ireland Limited

    Schizophrenia

    phase 2 small molecule terminated

    1 trial

  44. Gliolan 30 mg/ml powder for oral solution.

    Photonamic GmbH & Co. KG

    Glioblastoma

    phase 2 small molecule active

    1 trial

  45. Glofitamab

    Peking University Third Hospital

    MCL

    phase 2 small molecule active

    1 trial

  46. GlyT-1 inhibitor-1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 small molecule completed

    1 trial

  47. I-131-CLR1404 Injection

    Cellectar Biosciences

    Glioma

    phase 2 small molecule terminated

    1 trial

  48. I3Y-MC-JPEH

    Eli Lilly Co.

    Glioma

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

135 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.