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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one in fed condition

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Abuse

    phase 1 small molecule terminated

    1 trial

  2. 400 mg Cannabidiol

    BRIGHT MINDS BIOSCIENCES INC.

    Chronic Pain

    phase 1 small molecule active

    1 trial

  3. 400 mg LX4211

    LEXICON PHARMACEUTICALS, INC.

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  4. 45-mg hydrocodone bitartrate extended-release tablet (crushed or intact)

    Teva Pharma GmbH

    Drug Abuse

    phase 1 small molecule completed

    1 trial

  5. 480 mg Piperaquine phosphate

    CNS Pharmaceuticals

    Malaria

    phase 1 small molecule completed

    1 trial

  6. 4D-110

    4D Molecular Therapeutics

    Choroideremia

    phase 1 mab active

    1 trial

  7. 5 mg/500 mg Glipizide Metformin Hydrochloride Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  8. 5 mg/500 mg METAGLIP™ Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  9. 50 mg LX3305 QD

    LEXICON PHARMACEUTICALS, INC.

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  10. 500 mg GLPG1837 as oral suspension

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  11. 500 mg [14C]-LX1606

    LEXICON PHARMACEUTICALS, INC.

    Carcinoid Syndrome

    phase 1 small molecule completed

    1 trial

  12. 50mg Ezogabine/retigabine

    GlaxoSmithKline

    Epilepsy

    phase 1 small molecule completed

    1 trial

  13. 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  14. 608

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Moderate to Severe Plaque Psoriasis

    phase 1 small molecule active

    1 trial

  15. 609A

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Solid Tumors

    phase 1 small molecule active

    2 trials

  16. 610

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    add-on Maintenance Treatment of Patients With Severe Eosinophilic Asthma

    phase 1 small molecule active

    1 trial

  17. 610 30mg group

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Asthma

    phase 1 small molecule active

    1 trial

  18. 626

    Jian Li

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  19. 626

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  20. 627

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 mab active

    1 trial

  21. 64Cu-DOTA-TLX592

    Telix Innovations

    Metastatic Prostate Cancer

    phase 1 small molecule completed

    1 trial

  22. 68-Ga PSMA11

    Telix Innovations

    Prostate Adenocarcinoma

    phase 1 small molecule active

    1 trial

  23. 68GA-FAPI-46

    Disc Medicine

    Peritoneal metastases

    phase 1 small molecule active

    1 trial

  24. 68Ga-AAZTA-NI-093

    The First People's Hospital of Lianyungang

    Prostate Cancer (Adenocarcinoma)

    phase 1 small molecule active

    1 trial

  25. 68Ga-BNU-PSMA

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 other active

    1 trial

  26. 68Ga-DOTA-FAPI, 177Lu-DOTA-FAPI

    The First People's Hospital of Lianyungang

    177Lu-DOTA-FAPI

    phase 1 small molecule active

    1 trial

  27. 68Ga-DOTA/NOTA-FAPI-04

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 small molecule active

    1 trial

  28. 68Ga-FAPI-04

    The First People's Hospital of Lianyungang

    Liver Fibrosis

    phase 1 small molecule active

    1 trial

  29. 68Ga-FAPI-04

    Jian Li

    Fibrosis

    phase 1 small molecule active

    1 trial

  30. 68Ga-FAPI-Biotin

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 small molecule active

    1 trial

  31. 68Ga-JH04

    The First People's Hospital of Lianyungang

    Malignant Neoplasm

    phase 1 small molecule active

    1 trial

  32. 68Ga-JH12

    The First People's Hospital of Lianyungang

    Malignant Neoplasm

    phase 1 small molecule active

    1 trial

  33. 68Ga-MGS5

    The First People's Hospital of Lianyungang

    Medullary Thyroid Carcinoma

    phase 1 small molecule active

    1 trial

  34. 68Ga-NNS309

    Novartis Pharmaceuticals

    Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule active

    1 trial

  35. 68Ga-NODAGA-SNA006

    The First People's Hospital of Lianyungang

    Solid Tumor

    phase 1 mab completed

    1 trial

  36. 68Ga-NOTA-MAL-Cys39-exendin-4

    The First People's Hospital of Lianyungang

    Insulinoma

    phase 1 small molecule active

    1 trial

  37. 68Ga-PSMA-11

    The First People's Hospital of Lianyungang

    Prostate Cancer

    phase 1 small molecule active

    1 trial

  38. 68Ga-Pentixafor

    The First People's Hospital of Lianyungang

    Lymphoma

    phase 1 small molecule active

    1 trial

  39. 89Zr-DFO-YS5

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 1 small molecule active

    1 trial

  40. 89Zr-DFOsq-olaratumab (89Zr-TLX300-CDx)

    Telix Innovations

    Soft Tissue Sarcoma

    phase 1 small molecule active

    1 trial

  41. 89Zr-Girentuximab

    Telix Innovations

    Clear Cell Renal Carcinoma

    phase 1 other completed

    1 trial

  42. 89Zr-Girentuximab

    Telix Innovations

    Urothelial Carcinoma

    phase 1 small molecule completed

    1 trial

  43. 89Zr-girentuximab

    Telix Innovations

    Carcinoma, Renal Cell

    phase 1 other completed

    1 trial

  44. 89Zr˗DFO˗REGN3504

    Regeneron UK Limited

    Advanced PD-L1 Positive Malignancies

    phase 1 small molecule terminated

    1 trial

  45. 89Zr˗DFO˗REGN5054

    Regeneron UK Limited

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  46. 9-ING-41

    ACTUATE THERAPEUTICS, INC.

    Refractory Cancer

    phase 1 small molecule terminated

    1 trial

  47. 90 mg dose of the hydrocodone bitartrate extended-release tablet administered as either two 45-mg tablets (Treatment A) or one 90-mg tablet (Treatment B).

    Teva Pharma GmbH

    Pain

    phase 1 small molecule completed

    1 trial

  48. 99mTc-QULIC-5-P1

    The First People's Hospital of Lianyungang

    Prostate Cancer Stage

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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