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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 39 of 99

  1. EDG-7500

    Edgewise Therapeutics

    Renal Impairments

    phase 1 small molecule completed

    1 trial

  2. EDG-7500

    Edgewise Therapeutics

    Hepatic Impairment (HI)

    phase 1 small molecule active

    1 trial

  3. EDG-7500

    Edgewise Therapeutics

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  4. EDP 305

    ENANTA PHARMACEUTICALS INC

    NASH

    phase 1 small molecule completed

    1 trial

  5. EDP 305

    ENANTA PHARMACEUTICALS INC

    Presumptive NAFLD

    phase 1 small molecule completed

    1 trial

  6. EDP-235

    ENANTA PHARMACEUTICALS INC

    SARS CoV 2 Infection

    phase 1 small molecule completed

    1 trial

  7. EDP-297

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis With Liver Fibrosis

    phase 1 small molecule completed

    1 trial

  8. EDP-305

    ENANTA PHARMACEUTICALS INC

    NASH - Nonalcoholic Steatohepatitis

    phase 1 small molecule completed

    2 trials

  9. EDP-322

    ENANTA PHARMACEUTICALS INC

    MRSA, SSTI

    phase 1 small molecule completed

    1 trial

  10. EDP-322

    ENANTA PHARMACEUTICALS INC

    Skin and Soft Tissue Infections

    phase 1 small molecule completed

    1 trial

  11. EDP-323

    ENANTA PHARMACEUTICALS INC

    RSV Infection

    phase 1 small molecule completed

    3 trials

  12. EDP-494

    ENANTA PHARMACEUTICALS INC

    Hepatitis C

    phase 1 small molecule completed

    1 trial

  13. EDP-514

    ENANTA PHARMACEUTICALS INC

    Hepatitis B

    phase 1 small molecule completed

    1 trial

  14. EDP-514

    ENANTA PHARMACEUTICALS INC

    Chronic HBV Infection

    phase 1 small molecule completed

    2 trials

  15. EDP-721

    ENANTA PHARMACEUTICALS INC

    Chronic Hepatitis B Virus Infection

    phase 1 small molecule terminated

    1 trial

  16. EDP-788

    ENANTA PHARMACEUTICALS INC

    Safety in Normal Volunteers

    phase 1 small molecule completed

    1 trial

  17. EDP-788

    ENANTA PHARMACEUTICALS INC

    Healthy

    phase 1 small molecule terminated

    1 trial

  18. EDP-978

    ENANTA PHARMACEUTICALS INC

    Chronic Inducible Urticaria

    phase 1 small molecule active

    1 trial

  19. EDP239

    ENANTA PHARMACEUTICALS INC

    Hepatitis C

    phase 1 small molecule completed

    1 trial

  20. ELI-002 2P

    Elicio Therapeutics

    Minimal Residual Disease

    phase 1 small molecule completed

    1 trial

  21. ELVN-001

    Enliven Therapeutics

    CML (Chronic Myelogenous Leukemia)

    phase 1 small molecule active

    1 trial

  22. ELVN-001

    Enliven Therapeutics

    Chronic Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  23. ELVN-002

    Enliven Therapeutics

    HER2-positive Breast Cancer

    phase 1 small molecule active

    1 trial

  24. ELVN-002

    Enliven Therapeutics

    HER2 Mutant Non-small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  25. ELX-02

    Eloxx Pharmaceuticals

    Impaired Renal Function

    phase 1 small molecule completed

    1 trial

  26. ELX-02

    Eloxx Pharmaceuticals

    Genetic Diseases

    phase 1 small molecule terminated

    1 trial

  27. EMBER: A Study of LY3484356 in Patients with Breast or Other Non-Breast Cancers

    Eli Lilly Co.

    Breast Cancer, Endometrial cancer

    phase 1 other active

    1 trial

  28. ENA-001

    BRIGHT MINDS BIOSCIENCES INC.

    Respiratory Depression

    phase 1 small molecule active

    1 trial

  29. ENMD-2076

    CASI Pharmaceuticals

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  30. ENMD-2076

    CASI Pharmaceuticals

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  31. ENMD-2076

    CASI Pharmaceuticals

    Relapsed or Refractory Hematological Malignancies

    phase 1 small molecule completed

    1 trial

  32. EP-104IAR

    EUPRAXIA PHARMACEUTICALS INC.

    Osteoarthritis, Knee

    phase 1 small molecule completed

    1 trial

  33. ES414

    Aptevo Therapeutics

    Prostate Cancer

    phase 1 mab completed

    1 trial

  34. ESAT6-CFP10

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 mab completed

    1 trial

  35. ESN364

    Astellas Pharma Inc

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  36. ET1402L1-ARTEMIS™ T cells -IV

    AEON Biopharma

    Hepatocellular Carcinoma

    phase 1 mab completed

    1 trial

  37. ETC-1002

    Esperion Therapeutics

    Safety Evaluation of Escalating Doses

    phase 1 small molecule completed

    1 trial

  38. ETC-1002 or placebo

    Esperion Therapeutics

    Mild Dyslipidemia

    phase 1 small molecule completed

    1 trial

  39. ETC-159

    BRIGHT MINDS BIOSCIENCES INC.

    With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer

    phase 1 small molecule active

    1 trial

  40. ETC-1907206

    BRIGHT MINDS BIOSCIENCES INC.

    Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)

    phase 1 small molecule terminated

    1 trial

  41. ETC-1922159

    BRIGHT MINDS BIOSCIENCES INC.

    Solid Tumors

    phase 1 small molecule active

    1 trial

  42. ETH-155008

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NHL

    phase 1 small molecule terminated

    1 trial

  43. ETH-155008

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NHL, Adult

    phase 1 small molecule active

    1 trial

  44. ETR028, ETR029, [ETR028 + ETR029] or HCBT

    BRIGHT MINDS BIOSCIENCES INC.

    Acute Pain

    phase 1 small molecule active

    1 trial

  45. EVM16

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced or Recurrent Solid Tumors

    phase 1 mab active

    1 trial

  46. EVOLVE104

    United Therapeutics Europe Ltd

    Bladder Cancer

    phase 1 small molecule active

    1 trial

  47. EVT801

    KAZIA THERAPEUTICS LTD

    Solid Tumor, Adult

    phase 1 small molecule completed

    1 trial

  48. EXPAREL

    Pacira Ireland Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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