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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 35 of 99

  1. Cocaine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 1 small molecule completed

    1 trial

  2. Cocaine (IV)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule active

    1 trial

  3. Cocaine Self-adminstration

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  4. Cocaine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Induced Sympathoexciation and Vasoconstriction

    phase 1 small molecule terminated

    1 trial

  5. Cognitive-Behavioral Therapy

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 1 other completed

    1 trial

  6. Cohort 1 - TMP-301

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    1 trial

  7. Cohort 1 BEM + Ruzasvir

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  8. Cohort 1: Days 1-7 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. Days 8-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 BIK

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  9. Cohort 1: bococizumab 150 mg + rHuPH20

    HALOZYME THERAPEUTICS, INC.

    Healthy

    phase 1 mab terminated

    1 trial

  10. Combining drug-eluting bead chemoembolization and radioembolization for treatment of colorectal liver metastases: DEBIR90Y study

    Disc Medicine

    colorectal liver metastases

    phase 1 other active

    1 trial

  11. Comparative Bioavailability of Cabozantinib Film-Coated Tablets in Healthy Participants Under Fasting Conditions

    Lacuna Pharma Pty Ltd

    No medical condition.

    phase 1 other active

    1 trial

  12. Comparative Bioavailability of Levonorgestrel 52 mg Intrauterine System versus Mirena® in Healthy Pre-Menopausal, Non-Pregnant Female Participants.

    Laboratorios Tillomed Spain S.L.U

    No medical condition.

    phase 1 other active

    1 trial

  13. Comparative Bioavailability of Lisdexamfetamine Dimesylate 70 mg in Healthy Subjects Under Fasting Conditions

    Lacuna Pharma Pty Ltd

    No medical condition.

    phase 1 other active

    1 trial

  14. Comparative Bioavailability of Ruxolitinib 20 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.

    Lacuna Pharma Pty Ltd

    No medical condition.

    phase 1 other active

    1 trial

  15. Comparative Pharmacokinetic of S221237 Tablets in Healthy Participants Under Fed Conditions

    The George Institute

    No medical condition

    phase 1 other active

    1 trial

  16. Comparison between ABP 234 and Keytruda® (Pembrolizumab)

    Amgen

    Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer

    phase 1 other active

    1 trial

  17. Comparison of Prefilled syringe and Autoinjector presentations of FYB202

    Fresenius Kabi Australia Pty Limited

    Chronic inflammatory diseases

    phase 1 other active

    1 trial

  18. Comparison of the study drug CHF 1535 formulated with two different propellants to learn about drug levels in blood and safety after inhalation, with and without the use of the AeroChamber Plus® spacer, in healthy volunteers.

    Chiesi Farmaceutici S.p.A

    Asthma

    phase 1 other active

    1 trial

  19. Comparison of the study drug CHF 1535 formulated with two different propellants to learn about drug levels in blood and safety after inhalation, with and without the use of the Aerochamber Plus® spacer, in healthy volunteers.

    Chiesi Farmaceutici S.p.A

    Asthma and chronic obstructive pulmonary disease (COPD).

    phase 1 other active

    1 trial

  20. Computer algorithm for ATTR

    Alnylam Netherlands B.V.

    Transthyretin Amyloidosis

    phase 1 other terminated

    1 trial

  21. Concurrent chemotherapy

    Sun Yat-sen University

    Locally Advanced Lung Carcinoma

    phase 1 small molecule completed

    1 trial

  22. Conditioning Regimen (Rituxan, Siplizumab, Cyclophosphamide, Tegoprubart)

    Eledon Pharmaceuticals

    Kidney Failure

    phase 1 small molecule active

    1 trial

  23. Conditioning chemotherapy followed by AbTCR (anti-CD19/CD22)-T cell infusion

    The First People's Hospital of Lianyungang

    Diffuse Large B Cell Lymphoma (DLBCL)

    phase 1 small molecule active

    1 trial

  24. Control Group

    Tvardi Therapeutics

    Squamous Cell Carcinoma of Head and Neck

    phase 1 small molecule terminated

    1 trial

  25. Convalescent plasma

    Te Arai BioFarma Limited

    Convalescence

    phase 1 mab completed

    1 trial

  26. Cordyceps cicadae extract

    Hospital Authority, Hong Kong

    Myopia

    phase 1 mab completed

    1 trial

  27. Cordyceps cicadae extract

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Myopia

    phase 1 mab completed

    1 trial

  28. Cosibelimab

    TG THERAPEUTICS, INC.

    B-cell Non Hodgkin Lymphoma

    phase 1 small molecule terminated

    1 trial

  29. Creon 25.000, harde maagsapresistente capsules 25.000 eenheden, Creon 50000 Ph.Eur. lipase units, Creon 25000 Ph.Eur. lipase units, Creon 10000 Ph.Eur. lipase units, Creon 75000 Ph.Eur. lipase units, Creon® 10000 Capsules

    Lacuna Pharma Pty Ltd

    patients with cystic fibrosis suffering from pancreatic exocrine insufficiency

    phase 1 small molecule active

    1 trial

  30. Custirsen

    Teva Pharma GmbH

    Cardiac Conduction and Repolarization

    phase 1 small molecule completed

    1 trial

  31. Custirsen, paclitaxel and carboplatin

    Teva Pharma GmbH

    Cancer

    phase 1 small molecule completed

    1 trial

  32. Cyclophosphamide

    Iovance Biotherapeutics B.V.

    Locally Advanced Melanoma

    phase 1 small molecule active

    1 trial

  33. Cyclophosphamide

    Nektar Therapeutics UK Limited

    Recurrent Diffuse Large B-Cell Lymphoma

    phase 1 small molecule active

    1 trial

  34. Cyclophosphamide

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 1 small molecule active

    1 trial

  35. Cyclophosphamide and Fludarabine

    Chongqing Precision Biotech Co., Ltd

    Lung Cancer, Nonsmall Cell, Recurrent

    phase 1 small molecule active

    1 trial

  36. Cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Addiction

    phase 1 small molecule completed

    1 trial

  37. Cypep-1

    BRIGHT MINDS BIOSCIENCES INC.

    Cutaneous Warts

    phase 1 small molecule completed

    1 trial

  38. D/ChAd63-CA

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  39. D1ME100 (dengue-1 premembrane/envelope DNA vaccine)

    United Therapeutics Europe Ltd

    Dengue

    phase 1 mab completed

    1 trial

  40. DA-5210 10/500mg

    Dong Wang

    Healthy

    phase 1 small molecule completed

    1 trial

  41. DAB

    CNS Pharmaceuticals

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  42. DABRAFENIB MESYLATE, TMT212, CANAKINUMAB, DKY709, LXH254, TRAMETINIB DIMETHYL SULFOXIDE, NIR178, MCS110, LXH254, INC280, TMT212, PDR001, NIR178, PDR001, NIZ985, TRAMETINIB DIMETHYL SULFOXIDE, LAG525, NIR178, LXH254, DABRAFENIB MESYLATE

    Novartis Pharmaceuticals

    Different types of advanced cancer

    phase 1 small molecule active

    1 trial

  43. DAREONTM-9: A study to test how well different doses of BI 764532 are tolerated by people with small cell lung cancer when taken together with a single agent chemotherapy

    Boehringer Ingelheim

    relapsed/refractory extensive stage - small cell lung cancer (ES-SCLC)

    phase 1 other active

    1 trial

  44. DAREON™-7: A study to test how well different doses of BI 764532 in addition to chemotherapy are tolerated by people with advanced neuroendocrine cancers

    Boehringer Ingelheim

    Extra-pulmonary neuroendocrine carcinoma (epNEC), Neuroendocrine carcinoma (NEC) with unknown primary site, pulmonary Large cell neuroendocrine carcinoma (LCNEC)

    phase 1 other active

    1 trial

  45. DAREON™-8: A study to test how well different doses of BI 764532 in addition to standard of care are tolerated by people with advanced small cell lung cancer

    Boehringer Ingelheim

    Extensive-stage small cell lung carcinoma (ES-SCLC)

    phase 1 other active

    1 trial

  46. DC-CIK combined with regorafenib ,Iparomlimab and Tuvonralimab Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    DC-CIK Treatment

    phase 1 other active

    1 trial

  47. DCVac-L

    NORTHWEST BIOTHERAPEUTICS INC

    Ovarian Cancer

    phase 1 mab completed

    1 trial

  48. DCVax-Direct

    NORTHWEST BIOTHERAPEUTICS INC

    Brain Metastases

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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