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Intelligence · Clinical pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs 56
Sponsors 800
Drugs 4,222

Quick answer

NovaPharmaNews tracks 56 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Pipeline programs

Page 1 of 2

  1. 14341

    Disc Medicine

    Glioma

    phase 1 other active

    1 trial

  2. 2018-523-00US1

    Hutchmed Europe B.V.

    Lymphoma

    phase 1 other active

    1 trial

  3. 68Ga-FAPI-Biotin

    The First People's Hospital of Lianyungang

    Tumor

    phase 1 small molecule active

    1 trial

  4. 68Ga-Pentixafor

    The First People's Hospital of Lianyungang

    Lymphoma

    phase 1 small molecule active

    1 trial

  5. ALN-APOC3

    Regeneron UK Limited

    Dyslipidemia

    phase 1 small molecule completed

    1 trial

  6. AMX0114

    Amylyx Pharmaceuticals EMEA B.V.

    ALS

    phase 1 small molecule active

    1 trial

  7. APR-548 + Azacitidine

    Aprea Therapeutics

    MDS

    phase 1 small molecule terminated

    1 trial

  8. ASP8374

    Regeneron UK Limited

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  9. Abatacept

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Dermatomyositis

    phase 1 small molecule active

    1 trial

  10. Acetadote

    CUMBERLAND PHARMACEUTICALS INC

    Glioblastoma

    phase 1 small molecule active

    1 trial

  11. Azenosertib

    Zentalis Pharmaceuticals

    Osteosarcoma

    phase 1 small molecule completed

    1 trial

  12. BMN 111 administration via Injector Pen

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 1 other terminated

    1 trial

  13. BXCL501 80 Micrograms

    BioXcel Therapeutics

    Schizophrenia

    phase 1 small molecule active

    1 trial

  14. Biospecimen Collection

    United Therapeutics Europe Ltd

    Glioma

    phase 1 other active

    1 trial

  15. CLN-978

    Cullinan Therapeutics

    NHL

    phase 1 small molecule active

    1 trial

  16. CLN-978

    Cullinan Therapeutics

    SLE

    phase 1 small molecule active

    1 trial

  17. Chloroquine

    GlaxoSmithKline

    Malaria

    phase 1 small molecule completed

    1 trial

  18. D/ChAd63-CA

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  19. DBP-053-01

    Lacuna Pharma Pty Ltd

    Glioblastoma

    phase 1 other active

    1 trial

  20. DP CD8 TIL

    Phio Pharmaceuticals

    HNSCC

    phase 1 mab active

    1 trial

  21. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  22. FB102

    Forteo

    Vitiligo

    phase 1 small molecule active

    1 trial

  23. FMP012 with AS01B adjuvant system

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  24. FMP1/AS02A

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  25. Group 1: 10 ug FMP012 with 2 ug GLA-SE

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  26. Imatinib Mesylate

    Inhibikase Therapeutics

    CML

    phase 1 small molecule completed

    1 trial

  27. Infigratinib

    BridgeBio Oncology Therapeutics

    Glioma

    phase 1 small molecule terminated

    1 trial

  28. Ixazomib

    Takeda

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  29. LY03010/CT-EUR-102

    Lacuna Pharma Pty Ltd

    Schizophrenia

    phase 1 other active

    1 trial

  30. MBX 4291

    MBX Biosciences

    Obesity

    phase 1 small molecule active

    1 trial

  31. Motivational Interviewing

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia

    phase 1 other completed

    1 trial

  32. NC2022-01

    Disc Medicine

    Glioblastoma

    phase 1 other active

    1 trial

  33. Placebo

    Rhythm Pharmaceuticals Netherlands B.V.

    Obesity

    phase 1 small molecule completed

    1 trial

  34. Plasmodium falciparum Malaria Protein 010 (FMP010)

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  35. Poliorix

    GlaxoSmithKline

    Poliomyelitis

    phase 1 mab completed

    1 trial

  36. RT-114 is the RaniPill capsule with PG-102 for the treatment of obesity

    Rani Therapeutics Holdings

    Obesity

    phase 1 other active

    1 trial

  37. Recombinant oncolytic herpes simplex virus type Ⅰ (R130)

    Shanghai University of Traditional Chinese Medicine

    Osteosarcoma

    phase 1 small molecule active

    1 trial

  38. Risperidone

    The First People's Hospital of Lianyungang

    Schizophrenia

    phase 1 small molecule active

    1 trial

  39. Roflumilast

    Takeda

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  40. SOC + TSC-100

    TScan Therapeutics

    AML

    phase 1 small molecule active

    1 trial

  41. SPD489 (Lisdexamfetamine dimesylate)

    Takeda

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  42. SP_MH20VYX

    AXIM BIOTECHNOLOGIES, INC.

    AML

    phase 1 small molecule active

    1 trial

  43. Selinexor

    Karyopharm Therapeutics Inc

    Amyloid

    phase 1 small molecule terminated

    1 trial

  44. Selinexor

    Karyopharm Therapeutics Inc

    Liposarcoma

    phase 1 small molecule terminated

    1 trial

  45. TAK-058

    Takeda

    Schizophrenia

    phase 1 small molecule terminated

    1 trial

  46. TAK-063

    Takeda

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  47. TEV-53408

    Teva Pharma GmbH

    Vitiligo

    phase 1 small molecule active

    1 trial

  48. TG-1801

    TG THERAPEUTICS, INC.

    CLL

    phase 1 mab terminated

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

56 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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