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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 56 of 99

  1. Lendormin tablet

    Boehringer Ingelheim

    Healthy

    phase 1 small molecule completed

    1 trial

  2. Lenvatinib

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma Stage IIIa

    phase 1 small molecule active

    1 trial

  3. Letrozole

    Context Therapeutics

    Metastatic Breast Cancer

    phase 1 small molecule terminated

    1 trial

  4. Leukocyte Interleukin, Injection 200IU

    United Therapeutics Europe Ltd

    Condyloma

    phase 1 small molecule terminated

    1 trial

  5. Levetiracetam

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    4 trials

  6. Levodopa

    Blackmores Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  7. Levodopa 250mg and Carbidopa 25mg Test Drug tablet

    Laboratorios Tillomed Spain S.L.U

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  8. Levodopa Cyclops®

    BRIGHT MINDS BIOSCIENCES INC.

    Parkinson

    phase 1 other completed

    1 trial

  9. Liberase Enzyme (Roche)

    Blackmores Limited

    Pulmonary Alveolar Proteinosis

    phase 1 small molecule active

    1 trial

  10. Lidocaine patch

    BRIGHT MINDS BIOSCIENCES INC.

    Heat Effect

    phase 1 small molecule completed

    1 trial

  11. Lifestyle counseling

    BRIGHT MINDS BIOSCIENCES INC.

    Adherence

    phase 1 other completed

    1 trial

  12. Lifileucel (LN-144)

    Iovance Biotherapeutics B.V.

    Metastatic Melanoma

    phase 1 mab active

    1 trial

  13. Lifileucel (LN-144/LN-145)

    Iovance Biotherapeutics B.V.

    Uveal Melanoma

    phase 1 mab active

    1 trial

  14. Lifirafenib

    BEONE MEDICINES AUS PTY LTD

    Solid Tumor, Adult

    phase 1 small molecule completed

    1 trial

  15. Light Power Density and Light Duration 40 mW/cm²*1000s

    The First People's Hospital of Lianyungang

    Healthy Adult Subjects

    phase 1 other completed

    1 trial

  16. Linperlisib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 small molecule terminated

    1 trial

  17. Linperlisib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory Large Granular T Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  18. Lintuzumab AC 225

    Actinium Pharmaceuticals

    Refractory Multiple Myeloma

    phase 1 small molecule terminated

    1 trial

  19. Lipegfilgrastim

    Teva Pharma GmbH

    Ewing Family of Tumors, Rhabdomyosarcoma

    phase 1 small molecule completed

    1 trial

  20. Lipoaspiration

    REVIVA PHARMACEUTICALS HOLDINGS, INC.

    Hereditary Corneal Dystrophy

    phase 1 other active

    1 trial

  21. Liposomal Bupivacaine 13.3

    Pacira Ireland Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  22. Liposomal Mitoxantrone Hydrochloride dose level 1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  23. Liposomal bupivacaine

    United Therapeutics Europe Ltd

    Pain, Postoperative

    phase 1 small molecule completed

    1 trial

  24. Lipotecan

    Taiwan Liposome Company

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  25. Liraglutide injection,RD12014

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes

    phase 1 small molecule completed

    1 trial

  26. Lisdexamfetamine Dimesylate

    Takeda

    Healthy

    phase 1 small molecule terminated

    1 trial

  27. Lisdexamfetamine Dimesylate

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  28. Lisdexamfetamine Dimesylate (LDX)

    Takeda

    Attention-Deficit Hyperactivity Disorder

    phase 1 small molecule completed

    1 trial

  29. Litapiprant Tablet

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Asthma

    phase 1 small molecule completed

    1 trial

  30. Livmoniplimab, Budigalimab

    AbbVie Deutschland GmbH & Co. KG

    Locally Advanced or Metastatic Solid Tumors, Solid Tumors

    phase 1 small molecule active

    1 trial

  31. Lobeline

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule active

    1 trial

  32. Locametz 25 micrograms kit for radiopharmaceutical preparation, -, Pluvicto 1 000 MBq/mL solution for injection/infusion

    Novartis Pharmaceuticals

    Metastatic Castration-Resistant Prostate Cancer

    phase 1 small molecule active

    1 trial

  33. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  34. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 1 small molecule completed

    1 trial

  35. Lofexidine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Related Disorders

    phase 1 small molecule terminated

    1 trial

  36. Lofexidine (granules for reconstitution)

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  37. Lofexidine HCl

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  38. Lofexidine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers Will be Treated With Lofexidine to Understand the Absolute Bioavailability and Mass Balance Recovery of the Product

    phase 1 small molecule completed

    1 trial

  39. Lofexidine hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Normal Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  40. Loncastuximab Tesirine

    ADC Therapeutics SA

    B-Cell Non-Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  41. Loncastuximab Tesirine and Acalabrutinib

    ADC Therapeutics SA

    Chronic Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  42. Loncastuximab Tesirine and Durvalumab

    ADC Therapeutics SA

    Diffuse Large B-Cell Lymphoma

    phase 1 small molecule terminated

    1 trial

  43. Loncastuximab tesirine and rituximab (Lonca-R)

    ADC Therapeutics SA

    Central Nervous System Lymphoma

    phase 1 small molecule active

    1 trial

  44. Lopinavir/Ritonavir 200 mg/50 mg Film Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  45. Lorcaserin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    1 trial

  46. Losartan

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  47. Losartan potassium

    United Therapeutics Europe Ltd

    Emotional Processing

    phase 1 small molecule active

    1 trial

  48. Losartan potassium 50mg

    United Therapeutics Europe Ltd

    Social Cognition

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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