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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 54 of 99

  1. Ketorolac

    United Therapeutics Europe Ltd

    Pain, Post-operative

    phase 1 small molecule completed

    1 trial

  2. Keverprazan

    The First People's Hospital of Lianyungang

    Helicobacter Pylori Infection

    phase 1 small molecule active

    1 trial

  3. Kindolor Tosylate

    BRIGHT MINDS BIOSCIENCES INC.

    Chronic Pain

    phase 1 small molecule terminated

    1 trial

  4. Koselugo 25 mg hard capsules, Koselugo 10 mg hard capsules

    AstraZeneca AB

    Neurofibromatosis Type 1 (NF1) Related Plexiform Neurofibromas (PN)

    phase 1 small molecule active

    1 trial

  5. Kristalose

    CUMBERLAND PHARMACEUTICALS INC

    Bowel Evacuant Prior to Colonoscopy

    phase 1 small molecule completed

    1 trial

  6. Kukoamine B Mesilate

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 small molecule completed

    1 trial

  7. L-dopa / carbidopa / entacapone (LCE)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Abuse

    phase 1 small molecule completed

    1 trial

  8. LB-100 for Injection

    LIXTE BIOTECHNOLOGY HOLDINGS, INC.

    Tumors

    phase 1 small molecule completed

    1 trial

  9. LB1901

    Nanjing Legend Biotech Co.

    T-Cell Lymphoma

    phase 1 mab active

    1 trial

  10. LB1908

    Nanjing Legend Biotech Co.

    Gastric Cancer

    phase 1 mab active

    1 trial

  11. LB2102

    Nanjing Legend Biotech Co.

    Small Cell Lung Cancer Extensive Stage

    phase 1 mab active

    1 trial

  12. LBR-101 IV

    Teva Pharma GmbH

    Bioavailability and Pharmacokinetics

    phase 1 mab completed

    1 trial

  13. LBT-3627

    Biotech Pharmaceutical Co.,

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  14. LCAR-AIO Cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Lymphocytic Leukemia

    phase 1 mab terminated

    1 trial

  15. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Multiple Sclerosis (MS)

    phase 1 mab active

    1 trial

  16. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab terminated

    1 trial

  17. LCAR-AIO T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial

  18. LCAR-AIO cells product

    Nanjing Legend Biotech Co.

    B-cell Lymphoma Recurrent

    phase 1 mab terminated

    1 trial

  19. LCAR-AMDR Cells Product

    Nanjing Legend Biotech Co.

    Acute Myeloid Leukemia

    phase 1 mab terminated

    1 trial

  20. LCAR-B4822M CAR-T Cell Immunotherapy

    Nanjing Legend Biotech Co.

    Refractory or Relapsed Multiple Myeloma

    phase 1 small molecule active

    1 trial

  21. LCAR-BCDR cells product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Multiple Myeloma

    phase 1 mab terminated

    1 trial

  22. LCAR-BCX cells product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Multiple Myeloma

    phase 1 mab active

    1 trial

  23. LCAR-C182A cells

    Nanjing Legend Biotech Co.

    Gastric Cancer

    phase 1 mab terminated

    1 trial

  24. LCAR-C18S cells

    Nanjing Legend Biotech Co.

    Solid Tumors, Adult

    phase 1 mab terminated

    1 trial

  25. LCAR-G08 cells

    Nanjing Legend Biotech Co.

    Advanced Gastrointestinal Tumors

    phase 1 mab terminated

    1 trial

  26. LCAR-HL30 cells

    Nanjing Legend Biotech Co.

    Hodgkin's Lymphoma

    phase 1 mab active

    1 trial

  27. LCAR-M23 cells

    Nanjing Legend Biotech Co.

    Epithelial Ovarian Cancer

    phase 1 mab terminated

    1 trial

  28. LD and GC012F CAR-T Cell Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial

  29. LDK378

    Novartis Pharmaceuticals

    Anaplastic Lymphoma Kinase (ALK)

    phase 1 small molecule completed

    1 trial

  30. LDT600 (Telbivudine)

    Novartis Pharmaceuticals

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  31. LDX + Venlafaxine XR

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  32. LEE011

    Novartis Pharmaceuticals

    Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer

    phase 1 small molecule completed

    1 trial

  33. LENVIMA 10 mg hard capsules, LENVIMA 4 mg hard capsules, Bavencio 20 mg/mL concentrate for solution for infusion, LENVIMA 4 mg hard capsules, LENVIMA 10 mg hard capsules, LENVIMA 4 mg hard capsules, LENVIMA 10 mg hard capsules

    Merck Sharp and Dohme

    Central Nervous System Tumors

    phase 1 small molecule active

    1 trial

  34. LENVIMA 4 mg hard capsules, volrustomig, Kisplyx 10 mg hard capsules, Kisplyx 4 mg hard capsules, LENVIMA 10 mg hard capsules

    AstraZeneca AB

    Advanced Renal Cell Carcinoma

    phase 1 small molecule active

    1 trial

  35. LGD-6972

    LIGAND PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    2 trials

  36. LGD-6972 Solution

    LIGAND PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus (T2DM)

    phase 1 small molecule completed

    1 trial

  37. LGH447

    Novartis Pharmaceuticals

    Relapsed and Refractory Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  38. LGH447

    Novartis Pharmaceuticals

    AML and High Risk MDS

    phase 1 small molecule completed

    1 trial

  39. LN-144

    Iovance Biotherapeutics B.V.

    Stage IIIB Melanoma

    phase 1 mab terminated

    1 trial

  40. LN-145/LN-144

    Iovance Biotherapeutics B.V.

    Soft Tissue Sarcoma

    phase 1 mab active

    1 trial

  41. LNZ101 (Aceclidine /Brimonidine) ophthalmic solution

    LENZ Therapeutics

    Presbyopia

    phase 1 small molecule completed

    1 trial

  42. LOR-253 HCl

    Aptose Biosciences

    Advanced or Metastatic Solid Tumours

    phase 1 small molecule completed

    1 trial

  43. LPS (reference endotoxin, E. coli O113:H10:K:neg, manufactured under GMP)

    United Therapeutics Europe Ltd

    Cardiovascular Disease

    phase 1 small molecule completed

    1 trial

  44. LS11

    United Therapeutics Europe Ltd

    Neurofibroma

    phase 1 small molecule terminated

    1 trial

  45. LTI-03

    Shanghai Reinovax Biologics Co.,LTD

    Idiopathic Pulmonary Fibrosis

    phase 1 small molecule completed

    1 trial

  46. LUCAR-20S CAR-T cells

    Nanjing Legend Biotech Co.

    Diffuse Large B Cell Lymphoma

    phase 1 small molecule terminated

    1 trial

  47. LUCAR-20SP cells

    Nanjing Legend Biotech Co.

    Relapsed B-cell Non-Hodgkin Lymphoma

    phase 1 mab active

    1 trial

  48. LUCAR-B68 cells product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Multiple Myeloma

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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