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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 53 of 99

  1. KAI-9531

    Kailera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  2. KB301

    Krystal Biotech Netherlands B.V.

    Skin Roughness

    phase 1 mab active

    1 trial

  3. KB407 (Nebulization)

    Krystal Biotech Netherlands B.V.

    Cystic Fibrosis

    phase 1 mab active

    2 trials

  4. KB408 (Nebulization)

    Krystal Biotech Netherlands B.V.

    Alpha 1-Antitrypsin Deficiency

    phase 1 small molecule active

    1 trial

  5. KCP-330

    Karyopharm Therapeutics Inc

    Sarcoma

    phase 1 small molecule completed

    1 trial

  6. KFA115

    Novartis Pharmaceuticals

    Carcinoma, Non-Small-Cell Lung

    phase 1 small molecule active

    1 trial

  7. KHK6640

    KYOWA KIRIN AUSTRALIA PTY LTD

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  8. KISIMA-02 vaccine-based immunotherapy for patients with pancreatic cancer

    Boehringer Ingelheim

    G12D/G12V Pancreatic Ductal Adenocarcinoma

    phase 1 other active

    1 trial

  9. KK-LC-1 TCR-T cells

    Iovance Biotherapeutics B.V.

    Gastric Cancer

    phase 1 mab active

    1 trial

  10. KK8123

    KYOWA KIRIN AUSTRALIA PTY LTD

    X-linked hypophosphatemia.

    phase 1 small molecule active

    1 trial

  11. KNX100

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  12. KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

    Kura Oncology

    Pancreatic Ductal Adeno Carcinoma, Colorectal Cancer, Non- Small Cell Lung Cancer (NSCLC), Renal Cell Carcinoma

    phase 1 other active

    1 trial

  13. KO-947

    Kura Oncology

    Advanced Malignant Neoplasm

    phase 1 small molecule terminated

    1 trial

  14. KPL-404

    Kiniksa Pharmaceuticals International, plc

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  15. KPT-330

    Karyopharm Therapeutics Inc

    Diffuse Large B-Cell Lymphoma

    phase 1 small molecule completed

    1 trial

  16. KPT-330

    Karyopharm Therapeutics Inc

    Relapsed Acute Lymphoblastic Leukemia (ALL)

    phase 1 small molecule active

    1 trial

  17. KPT-330

    Karyopharm Therapeutics Inc

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  18. KPT-330

    Karyopharm Therapeutics Inc

    Hematological Malignancies

    phase 1 small molecule completed

    1 trial

  19. KPT-9274

    Karyopharm Therapeutics Inc

    Solid Tumors

    phase 1 small molecule terminated

    1 trial

  20. KPT-9274

    Karyopharm Therapeutics Inc

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  21. KRAS Vaccine with Poly-ICLC adjuvant

    United Therapeutics Europe Ltd

    Colorectal Cancer

    phase 1 small molecule active

    1 trial

  22. KSH01 injection

    TScan Therapeutics

    Solid Tumor

    phase 1 small molecule active

    1 trial

  23. KSH01 injection

    TScan Therapeutics

    TCR-T Cells

    phase 1 small molecule active

    1 trial

  24. KSHN001126 150mg

    Amneal Pharma Europe Ltd

    Healthy Postmenopausal Women

    phase 1 small molecule completed

    1 trial

  25. KSV01 Injection

    TScan Therapeutics

    B-ALL

    phase 1 small molecule active

    1 trial

  26. KSV01 Injection

    TScan Therapeutics

    Non-Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  27. KSX01-TCRT injection

    TScan Therapeutics

    TCR-T Cells

    phase 1 small molecule active

    1 trial

  28. KT-253

    Kymera Therapeutics

    Myeloid Malignancies

    phase 1 small molecule completed

    1 trial

  29. KT-333

    Kymera Therapeutics

    Non Hodgkin Lymphoma (NHL)

    phase 1 small molecule completed

    1 trial

  30. KT-413

    Kymera Therapeutics

    Non Hodgkin Lymphoma

    phase 1 small molecule completed

    1 trial

  31. KT-474/Placebo

    Kymera Therapeutics

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  32. KT-579

    Kymera Therapeutics

    Healthy Participants

    phase 1 small molecule active

    1 trial

  33. KT-621

    Kymera Therapeutics

    Healthy Participants Study

    phase 1 small molecule completed

    1 trial

  34. KVD824

    Kalvista Pharmaceuticals (Ireland) Limited

    Hereditary Angioedema

    phase 1 small molecule completed

    1 trial

  35. KVD824 Prototype 1 modified-release tablet

    Kalvista Pharmaceuticals (Ireland) Limited

    Hereditary Angioedema

    phase 1 small molecule completed

    1 trial

  36. KXV01 TCR Lentinvivo Injection

    The First People's Hospital of Lianyungang

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  37. KXV01 TCR Lentinvivo Injection

    The First People's Hospital of Lianyungang

    Advanced Solid Cancer

    phase 1 small molecule active

    1 trial

  38. KXV01 TCR Lentinvivo Injection

    TScan Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule active

    2 trials

  39. KYV-101

    Kyverna Therapeutics

    Idiopathic Inflammatory Myopathies

    phase 1 small molecule active

    1 trial

  40. KYV-101 (Biological) - 0.33 ×10^8 cells

    Kyverna Therapeutics

    Progressive Multiple Sclerosis

    phase 1 mab active

    1 trial

  41. KYV-101 anti-CD19 CAR-T cell therapy

    Kyverna Therapeutics

    Multiple Sclerosis

    phase 1 mab active

    1 trial

  42. Kang Guan Recipe (Treat)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Coronavirus Disease 2019

    phase 1 other completed

    1 trial

  43. Kangdaprevir Sodium Tablet

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Hepatitis c

    phase 1 small molecule completed

    1 trial

  44. Ketamine

    United Therapeutics Europe Ltd

    Acute Depression

    phase 1 small molecule terminated

    1 trial

  45. Ketamine

    Takeda

    Ketamine-Induced Brain Activity Changes

    phase 1 small molecule completed

    1 trial

  46. Ketamine

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  47. Ketamine (Ketalar)

    Grace Therapeutics

    Pain

    phase 1 small molecule active

    1 trial

  48. Ketamine (Ketalar) Dose Level 1

    Grace Therapeutics

    Pain, Postoperative

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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