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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. LUCAR-DKS1 NK cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab active

    1 trial

  2. LUCAR-E9D or LUCAR-E9K cells product

    The First People's Hospital of Lianyungang

    B-cell Non-Hodgkin Lymphoma Recurrent B-cell Non-Hodgkin Lymphoma Refractory

    phase 1 mab active

    1 trial

  3. LUCAR-G39D cells product

    Nanjing Legend Biotech Co.

    B-Cell Non-Hodgkin Lymphoma-Recurrent

    phase 1 mab active

    1 trial

  4. LUCAR-G39P cells product

    The First People's Hospital of Lianyungang

    Relapsed and Refractory B-cell Non-Hodgkin Lymphoma

    phase 1 mab terminated

    1 trial

  5. LUCAR-G79 T cells

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Autoimmune Diseases

    phase 1 mab active

    1 trial

  6. LUCAR-G79D T cells

    Nanjing Legend Biotech Co.

    Systemic Lupus Erythematosus (SLE)

    phase 1 mab active

    1 trial

  7. LVIVO-TaVec200 product

    The First People's Hospital of Lianyungang

    Multiple Myeloma

    phase 1 mab active

    1 trial

  8. LVIVO-TaVec400 product

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Multiple Myeloma (MM)

    phase 1 mab active

    1 trial

  9. LVIVO-TaVec400 product

    Nanjing Legend Biotech Co.

    Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)

    phase 1 mab active

    1 trial

  10. LX1001

    Lexeo Therapeutics

    Alzheimer Disease

    phase 1 mab active

    1 trial

  11. LX3305

    LEXICON PHARMACEUTICALS, INC.

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  12. LX4211

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  13. LX4211

    LEXICON PHARMACEUTICALS, INC.

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    2 trials

  14. LX4211 400 mg

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  15. LX4211 400 mg

    LEXICON PHARMACEUTICALS, INC.

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  16. LX4211 800 mg

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  17. LY007

    The First People's Hospital of Lianyungang

    B-NHL

    phase 1 small molecule active

    1 trial

  18. LY2456302

    Krystal Biotech Netherlands B.V.

    Anxiety Disorders

    phase 1 small molecule terminated

    1 trial

  19. LY3039478

    Eli Lilly and Company

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  20. LY3053102

    Eli Lilly and Company

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  21. LY3209590 (SC)

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  22. LY3471851

    Nektar Therapeutics UK Limited

    Healthy

    phase 1 small molecule completed

    4 trials

  23. LY3471851

    Nektar Therapeutics UK Limited

    Dermatitis, Atopic

    phase 1 small molecule completed

    1 trial

  24. LY3484356

    Eli Lilly and Company

    Breast Neoplasms

    phase 1 small molecule active

    1 trial

  25. LY3493269

    Eli Lilly and Company

    Healthy

    phase 1 small molecule terminated

    1 trial

  26. LY3493269 - SC

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  27. LY3532226

    Eli Lilly and Company

    Obesity

    phase 1 small molecule completed

    1 trial

  28. LY3537021

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  29. LY3819469

    Eli Lilly and Company

    Healthy

    phase 1 small molecule completed

    1 trial

  30. LY4006896

    Eli Lilly and Company

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  31. Lamivudine

    GlaxoSmithKline

    Hepatitis B, Chronic

    phase 1 small molecule completed

    1 trial

  32. Lamotrigine

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  33. Lamotrigine 25 mg Chewable Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  34. Lamotrigine Extended Release

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  35. Lanadelumab

    Takeda

    COVID-19 Pneumonia

    phase 1 small molecule terminated

    1 trial

  36. Lanadelumab

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  37. Lanraplenib.

    Gilead Sciences Ireland UC

    Inflammatory Disease

    phase 1 small molecule completed

    1 trial

  38. Lansoprazole

    Takeda

    Gastroesophageal Reflux Disease

    phase 1 small molecule completed

    2 trials

  39. Lansoprazole

    PUMA BIOTECHNOLOGY, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  40. Lansoprazole

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    3 trials

  41. Lansoprazole capsules

    The First People's Hospital of Lianyungang

    Effect of Drugs

    phase 1 small molecule completed

    1 trial

  42. Lanthanum carbonate Granule Formulation

    Takeda

    End Stage Renal Disease

    phase 1 small molecule completed

    1 trial

  43. Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  44. Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Esophageal Cancer

    phase 1 small molecule active

    1 trial

  45. Larotrectinib

    Hospital Authority, Hong Kong

    High Grade Glioma

    phase 1 small molecule active

    1 trial

  46. Leflunomide 20 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  47. Lenalidomide (CC-5013)

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  48. Lenalidomide or Pomalidomide

    ONCOLYTICS BIOTECH INC

    Multiple Myeloma

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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