🇺🇸 FDA

Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 59 of 99

  1. MV-LASV

    Harmony Biosciences Holdings

    Lassa Virus Infection

    phase 1 mab completed

    1 trial

  2. MVA-NP+M1

    Barinthus Biotherapeutics plc.

    Human Volunteers

    phase 1 mab completed

    1 trial

  3. MVC-101

    Takeda

    Solid Tumour

    phase 1 mab terminated

    1 trial

  4. MWN109 tablet

    Shanghai University of Traditional Chinese Medicine

    Overweight or Obesity

    phase 1 small molecule active

    1 trial

  5. MYCOPHENOLATE MOFETIL, INFLIXIMAB, Rilvegostomig, Rilvegostomig, volrustomig, CARBOPLATIN, IMFINZI 50 mg/mL concentrate for solution for infusion., Datopotamab deruxtecan, AZD7789

    AstraZeneca AB

    Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial

  6. MZE001

    Maze Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  7. Macitentan 10 mg tablet, once daily.

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Coronary Microvascular Angina

    phase 1 small molecule active

    1 trial

  8. Magellan®

    United Therapeutics Europe Ltd

    Acute Burns

    phase 1 other active

    1 trial

  9. Mammaglobin-A DNA Vaccine

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 1 mab active

    1 trial

  10. ManNAc

    Ultragenyx UK Limited

    Hereditary Inclusion Body Myopathy (HIBM)

    phase 1 small molecule completed

    1 trial

  11. MapMySmoke

    United Therapeutics Europe Ltd

    Smoking

    phase 1 other active

    1 trial

  12. Maribavir

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  13. Maribavir (400 mg)

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  14. Maribavir Commercial Tablet Formulation

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  15. Marijuana

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis

    phase 1 small molecule completed

    1 trial

  16. Marijuana via vape device

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking-Related Carcinoma

    phase 1 small molecule active

    1 trial

  17. Marinol 10Mg Capsule TMS Sham

    BRIGHT MINDS BIOSCIENCES INC.

    Neurosciences

    phase 1 small molecule completed

    1 trial

  18. MarzAA (marzeptacog alfa [activated])

    CATALYST PHARMACEUTICALS, INC.

    Hemophilia A

    phase 1 mab completed

    1 trial

  19. Mass Balance Study of [14C] ABBV-932 in Healthy Male Volunteers

    AbbVie Deutschland GmbH & Co. KG

    Healthy Volunteers

    phase 1 other active

    1 trial

  20. Mass Balance and Absolute Oral Bioavailability of [14C]VH4524184

    ViiV Healthcare Pty Ltd

    human immunodeficiency virus (HIV)

    phase 1 other active

    1 trial

  21. Master Protocol of Sotorasib (AMG 510) in Subjects with Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreaK 101)

    Amgen

    Advanced Solid Tumors Kirsten Rat Sarcoma (KRAS) pG12C Mutation

    phase 1 other active

    1 trial

  22. Mavorixafor

    X4 Pharmaceuticals, Inc

    Hepatic Insufficiency

    phase 1 small molecule active

    1 trial

  23. Mavorixafor

    X4 Pharmaceuticals, Inc

    Waldenstrom's Macroglobulinemia

    phase 1 small molecule completed

    1 trial

  24. Mavorixafor

    X4 Pharmaceuticals, Inc

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  25. Medium THC

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Impairment

    phase 1 small molecule completed

    1 trial

  26. Meloxicam 15 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  27. Memantine

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 1 small molecule completed

    1 trial

  28. Meningococcal ACYW135 Polysaccharide Conjugate Vaccine

    BRIGHT MINDS BIOSCIENCES INC.

    Meningitis, Meningococcal

    phase 1 mab active

    1 trial

  29. Menopur 150 international units

    NORTHWEST BIOTHERAPEUTICS INC

    Pregnancy

    phase 1 small molecule terminated

    1 trial

  30. Mepolizumab

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Subjects

    phase 1 mab completed

    1 trial

  31. Mesalamine

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  32. Mesenchymal Stem Cell Infusion

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Effector Cell Associated Hematotoxicity

    phase 1 mab active

    1 trial

  33. Metabolically Armed CD19 CAR-T cells

    Anhui Provincial Hospital

    Acute Lymphoblastic Leukemia

    phase 1 small molecule active

    1 trial

  34. Metformin

    United Therapeutics Europe Ltd

    Tendinopathy

    phase 1 small molecule active

    1 trial

  35. Metformin

    The First People's Hospital of Lianyungang

    Type2 Diabetes

    phase 1 small molecule active

    1 trial

  36. Methadone

    BRIGHT MINDS BIOSCIENCES INC.

    Opiate-Related Disorders

    phase 1 small molecule completed

    1 trial

  37. Methamphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Stimulant Use

    phase 1 small molecule completed

    1 trial

  38. Methamphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Use Disorder

    phase 1 small molecule completed

    1 trial

  39. Methamphetamine (Desoxyn®)

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Abuse

    phase 1 small molecule completed

    1 trial

  40. Methosulide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 small molecule completed

    1 trial

  41. Methotrexate

    Sana Biotechnology

    Chronic Plaque Psoriasis

    phase 1 small molecule active

    1 trial

  42. Methotrexate - Amneal

    Amneal Pharma Europe Ltd

    Psoriasis

    phase 1 small molecule active

    1 trial

  43. Methotrexate PK (in combination with Novobiocin) in RA patients

    Lacuna Pharma Pty Ltd

    Rheumatoid arthritis

    phase 1 other active

    1 trial

  44. Methylene Blue (50 mg/10ml)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Cancer

    phase 1 small molecule active

    1 trial

  45. Methylphenidate

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule completed

    1 trial

  46. Methylphenidate

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use Disorder

    phase 1 small molecule active

    1 trial

  47. Metronidazole

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  48. Metronidazole + MMX Mesalazine/mesalamine placebo

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.