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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 52 of 99

  1. Ipilimumab

    Regeneron UK Limited

    Stage III Prostate Cancer

    phase 1 mab terminated

    1 trial

  2. Irinotecan Accord 20 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Gastric cancer

    phase 1 small molecule active

    1 trial

  3. Irinotecan liposome II combination therapy regimen

    Chongqing Claruvis Pharmaceutical Co.,

    Non-Muscle Invasive Bladder Urothelial Carcinoma

    phase 1 small molecule active

    1 trial

  4. Isradipine

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 1 small molecule completed

    1 trial

  5. Itacitinib

    Incyte

    Acute Graft-versus-host Disease

    phase 1 small molecule completed

    1 trial

  6. Itepekimab AI

    Regeneron UK Limited

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule completed

    1 trial

  7. Itraconazole

    United Therapeutics Europe Ltd

    Non-small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  8. Itraconazole

    COGNITION THERAPEUTICS INC

    Drug Interaction

    phase 1 small molecule completed

    1 trial

  9. Ivosidenib

    Agios Netherlands B.V.

    IDH1 Mutation Myeloid Neoplasms

    phase 1 small molecule completed

    1 trial

  10. Ixazomib

    Takeda

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  11. Ixazomib

    Takeda

    Light-Chain Amyloidosis

    phase 1 small molecule completed

    1 trial

  12. Ixazomib

    Takeda

    Lupus Nephritis

    phase 1 small molecule terminated

    1 trial

  13. Ixazomib

    Takeda

    Precursor Cell Lymphoblastic Leukemia-lymphoma

    phase 1 small molecule terminated

    1 trial

  14. Ixazomib

    Takeda

    Relapsed and Refractory Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  15. Ixazomib

    Takeda

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  16. Ixazomib (NINLARO®) capsules / Matching placebo capsules

    Takeda

    Relapsing Remitting Multiple Sclerosis

    phase 1 small molecule active

    1 trial

  17. Ixazomib 2.5 mg

    Takeda

    Nonhematologic Malignancies

    phase 1 small molecule completed

    1 trial

  18. J1O-MC-JZHD: A Phase 1 Study of Aurora Kinase A Inhibitor LY3295668 Erbumine as a Single Agent and in Combination in Patients With Relapsed/Refractory Neuroblastoma

    Eli Lilly Co.

    Neuroblastoma

    phase 1 other active

    1 trial

  19. JADE101

    Jade Biosciences

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  20. JADE101

    Jade Biosciences

    Healthy Volunteers (HV)

    phase 1 small molecule active

    1 trial

  21. JADE201

    Jade Biosciences

    Rhematoid Arthritis

    phase 1 small molecule active

    1 trial

  22. JANX007

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  23. JANX008

    Janux Therapeutics

    Non-Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  24. JANX011

    Janux Therapeutics

    Autoimmune

    phase 1 small molecule active

    1 trial

  25. JANX014

    Janux Therapeutics

    Prostate Cancer

    phase 1 mab active

    1 trial

  26. JDtic

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule terminated

    1 trial

  27. JNJ-53718678

    Janssen Cilag International NV

    Respiratory Syncytial Virus Infections

    phase 1 small molecule terminated

    1 trial

  28. JNJ-56021927

    Janssen Cilag International NV

    Prostatic Neoplasms, Castration-Resistant

    phase 1 small molecule completed

    1 trial

  29. JR-441

    Lacuna Pharma Pty Ltd

    Mucopolysaccharidosis type IIIA (MPS IIIA)

    phase 1 small molecule active

    1 trial

  30. JR8603

    JiaRay Group

    Solid Tumors

    phase 1 small molecule active

    1 trial

  31. JSB462

    Novartis Pharmaceuticals

    Metastatic Prostate Cancer (mCRPC)

    phase 1 small molecule active

    1 trial

  32. JSP191

    Jasper Therapeutics

    Lower-risk Myelodysplastic Syndrome

    phase 1 small molecule terminated

    1 trial

  33. JWCAR029 (CD19-targeted Chimeric Antigen Receptor Cells)

    Shanghai University of Traditional Chinese Medicine

    Diffuse Large B Cell Lymphoma

    phase 1 mab completed

    1 trial

  34. JWCAR129

    The First People's Hospital of Lianyungang

    Safety and Efficacy

    phase 1 mab active

    1 trial

  35. JWK002

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    X Linked Retinoschisis

    phase 1 small molecule active

    1 trial

  36. JWK007 Single intravenous infusion administration

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Duchenne Muscular Dystrophy

    phase 1 mab active

    1 trial

  37. JY306 universal NK cell injection

    The First People's Hospital of Lianyungang

    Relapsed or Refractory Hematological Malignancies

    phase 1 mab active

    1 trial

  38. JYEST Cell Injection Infusion

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Prevention of EBV Infection After Allogeneic Hematopoietic Stem Cell Transplantation

    phase 1 mab active

    1 trial

  39. JZP047

    Jazz Pharmaceuticals Ireland Limited

    Healthy Participants

    phase 1 small molecule active

    1 trial

  40. JZP341

    Jazz Pharmaceuticals Ireland Limited

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  41. JZP441

    Jazz Pharmaceuticals Ireland Limited

    Narcolepsy

    phase 1 small molecule terminated

    1 trial

  42. JZP441

    Jazz Pharmaceuticals Ireland Limited

    Healthy Participants

    phase 1 small molecule completed

    2 trials

  43. JZP815

    Jazz Pharmaceuticals Ireland Limited

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  44. JZP898

    Jazz Pharmaceuticals Ireland Limited

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  45. Jakavi 10 mg tablets, CELECOXIB , Navitoclax, Navitoclax, Jakavi 10 mg tablets, Jakavi 5 mg tablets, Jakavi 5 mg tablets, Jakavi 5 mg tablets, Jakavi 10 mg tablets

    AbbVie Deutschland GmbH & Co. KG

    Myelofibrosis, Myeloproliferative Neoplasms

    phase 1 small molecule active

    1 trial

  46. Jianpi Qinghua granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nonerosive Reflux Disease

    phase 1 small molecule active

    1 trial

  47. Jiedu Tongluo granules

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Post-stroke Depression

    phase 1 small molecule completed

    1 trial

  48. Jiu-wei-zhen-xiao Granule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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