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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. GRT-1C102: A randomized, double-blind, placebo-controlled dose escalation study to evaluate the safety, tolerability, and pharmacokinetics/pharmacodynamics of GRT-001 after subcutaneous administrations to healthy subjects (MONOSqut trial).

    Rani Therapeutics Holdings

    Ulcerative colitis

    phase 1 other active

    1 trial

  2. GRoningen Early-PD Ambroxol Treatment Pharmacokinetics

    Disc Medicine

    Parkinson's disease

    phase 1 other active

    1 trial

  3. GS-0272

    Gilead Sciences Ireland UC

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial

  4. GS-2829

    Gilead Sciences Ireland UC

    Chronic Hepatitis B

    phase 1 mab completed

    1 trial

  5. GS-5245 tablets 175 mg, GS-5245 tablets 350 mg

    Gilead Sciences Pty Limited

    Renal Impairment

    phase 1 small molecule active

    1 trial

  6. GSBR-1290

    Structure Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  7. GSBR-1290 (Capsule/Tablet)

    Structure Therapeutics

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  8. GSK2269557 ELLIPTA DPI

    GlaxoSmithKline

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  9. GSK2879552

    GlaxoSmithKline

    Leukaemia, Myelocytic, Acute

    phase 1 small molecule terminated

    1 trial

  10. GSK525762

    GlaxoSmithKline

    Solid Tumours

    phase 1 small molecule terminated

    1 trial

  11. GSK5533524

    GlaxoSmithKline

    Neoplasms

    phase 1 small molecule active

    1 trial

  12. GSK961081

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    2 trials

  13. GSK961081 15mcg SD

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  14. GST-HG121 tablets

    Jian Li

    Pharmacokinetics

    phase 1 small molecule active

    1 trial

  15. GST-HG121 tablets

    The First People's Hospital of Lianyungang

    Pharmacokinetics

    phase 1 small molecule active

    1 trial

  16. GT-02287

    Gain Therapeutics

    Parkinson Disease

    phase 1 small molecule active

    1 trial

  17. GTB-5550

    GT Biopharma

    Tri-specific Killer Engager

    phase 1 small molecule active

    1 trial

  18. GTX-101

    Grace Therapeutics

    Postherpetic Neuralgia

    phase 1 small molecule active

    1 trial

  19. GTX-102 medium dose fast Period 1 and Period 2

    Grace Therapeutics

    Ataxia Telangiectasia

    phase 1 small molecule active

    1 trial

  20. GTX-104

    Grace Therapeutics

    Aneurysmal Subarachnoid Hemorrhage

    phase 1 small molecule completed

    1 trial

  21. GV20-0251

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HCC - Hepatocellular Carcinoma

    phase 1 small molecule active

    1 trial

  22. GX15-070MS

    Teva Pharma GmbH

    Chronic Lymphocytic Leukemia

    phase 1 small molecule completed

    1 trial

  23. GZ17-6.02

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  24. Ga68-Dolacga Injection

    Taiwan Liposome Company

    Safety Issues

    phase 1 small molecule completed

    1 trial

  25. Galidesivir

    Biocryst

    COVID-19

    phase 1 small molecule terminated

    1 trial

  26. Gallium-68 NODAGA-JR11

    The First People's Hospital of Lianyungang

    Neuroendocrine Tumors

    phase 1 small molecule active

    1 trial

  27. Gallium-68 citrate

    United Therapeutics Europe Ltd

    Prostatic Neoplasms

    phase 1 small molecule completed

    1 trial

  28. Garetosmab

    Regeneron UK Limited

    Obesity

    phase 1 small molecule terminated

    1 trial

  29. Gemtuzumab Ozogamicin

    Jazz Pharmaceuticals Ireland Limited

    Acute Myelogenous Leukemia

    phase 1 small molecule terminated

    1 trial

  30. Gilteritinib

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia With FLT3/ITD Mutation

    phase 1 small molecule active

    1 trial

  31. Givosiran

    Alnylam Netherlands B.V.

    Acute Intermittent Porphyria (AIP)

    phase 1 small molecule completed

    1 trial

  32. Glimepiride 4 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  33. Glucagon

    United Therapeutics Europe Ltd

    Type 1 Diabetes Mellitus With Hypoglycemia

    phase 1 small molecule completed

    1 trial

  34. Glucophage® XR 750 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  35. Glucose

    United Therapeutics Europe Ltd

    Diabetes Mellitus

    phase 1 other completed

    1 trial

  36. Glyburide

    United Therapeutics Europe Ltd

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  37. Glyburide/Metformin 5 mg/500 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  38. Glycerol Phenylbutyrate 1100 MG/ML [Ravicti]

    S.L

    STXBP1 Encephalopathy With Epilepsy, SLC6A1 Neurodevelopmental Disorder

    phase 1 small molecule active

    1 trial

  39. Gonadorelin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 other completed

    1 trial

  40. Gonadotrophin releasing hormone agonist(GnRHa)

    NORTHWEST BIOTHERAPEUTICS INC

    GnRHa;LPS

    phase 1 small molecule active

    1 trial

  41. Granisetron hydrochloride 1 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  42. Granulocyte Colony-Stimulating Factor

    United Therapeutics Europe Ltd

    Biliary Atresia

    phase 1 small molecule completed

    1 trial

  43. Group 1: 10 ug FMP012 with 2 ug GLA-SE

    United Therapeutics Europe Ltd

    Malaria

    phase 1 mab completed

    1 trial

  44. Group A

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Colorectal Cancer

    phase 1 mab active

    1 trial

  45. Group A

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma

    phase 1 mab active

    1 trial

  46. Group A Deactivated TENS with beeping sound (15-second interval)

    United Therapeutics Europe Ltd

    Healthy

    phase 1 other completed

    1 trial

  47. Guadecitabine

    United Therapeutics Europe Ltd

    Non Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  48. H5.001CBCFTR

    Ultragenyx UK Limited

    Cystic Fibrosis

    phase 1 gene therapy completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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