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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 48 of 99

  1. HSK3486

    The First People's Hospital of Lianyungang

    Healthy Elderly Subjects

    phase 1 small molecule completed

    1 trial

  2. HSK3486

    The First People's Hospital of Lianyungang

    Chronic Renal Impairment

    phase 1 small molecule completed

    1 trial

  3. HSV 2 Formulation 1

    Lxo Ireland Designated Activity Company

    Genital Herpes

    phase 1 mab terminated

    1 trial

  4. HTLP-onco-adult - A phase I/II Study evaluating the safety and the efficacy of Human T Lymphoid Progenitor (HTLP) injection to accelerate immune reconstitution after umbilical cord blood (UCB) transplantation in adult patients with hematologic malignancies

    Pari Pharma GmbH

    hematologic malignancies ; acute myeloid leukemias

    phase 1 other active

    1 trial

  5. HW071021 Tablets

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  6. HW071021 Tablets

    Wuhan Humanwell Innovative Drug Research and Development Center Limited Company

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  7. HW201877 capsules

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Participants

    phase 1 small molecule active

    1 trial

  8. HWK-007

    Whitehawk Therapeutics

    Endometrial Cancer

    phase 1 small molecule active

    1 trial

  9. HWK-016, MUCIN-16-targeted ADC

    CATALYST PHARMACEUTICALS, INC.

    PROC

    phase 1 small molecule active

    1 trial

  10. HWS116 Injection

    BRIGHT MINDS BIOSCIENCES INC.

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  11. HY-2003 (10 mg/ml), BELKYRA and placebo

    The First People's Hospital of Lianyungang

    Moderate or Severe Submental Fullness

    phase 1 small molecule active

    1 trial

  12. HYQVIA

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  13. Health Promotion and Education

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking-Related Carcinoma

    phase 1 other completed

    1 trial

  14. Hema-NeoTIL01

    The First People's Hospital of Lianyungang

    Leukemia, Myeloid, Acute

    phase 1 mab active

    1 trial

  15. Hemay005 tablet

    Anhui Hemay Pharmaceutical Co., Ltd

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule completed

    1 trial

  16. Hemay020

    Tianjin Hemay Pharmaceutical Co., Ltd

    Neoplasms，Non-Small Cell Lung Cancer

    phase 1 small molecule terminated

    1 trial

  17. Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer’s Disease (AD)

    IONIS PHARMACEUTICALS INC

    Alzheimer’s Disease in Individuals with Down Syndrome

    phase 1 other active

    1 trial

  18. Huafu Shengji Ointment

    Universal Integrated

    Diabetic Foot

    phase 1 small molecule active

    1 trial

  19. Humalog

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  20. Human Amniotic Epithelial Stem Cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Parkinson's Disease

    phase 1 mab completed

    1 trial

  21. Human Anti-PD-L1 Monoclonal Antibody Injection (LDP) Combined with Recombinant Anti-EGFR Human Mouse Chimeric Monoclonal Antibody Injection (CDP1)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Malignant Tumor

    phase 1 small molecule active

    1 trial

  22. Human BCMA targeted T Cells Injection

    The First People's Hospital of Lianyungang

    Multiple Myeloma

    phase 1 small molecule active

    1 trial

  23. Human Glucocerebrosidase (prGCD)

    Protalix BioTherapeutics

    Gaucher Disease

    phase 1 small molecule completed

    1 trial

  24. Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles (hUCMSC-EVs)

    Shanghai Zhongshan Hospital

    Interstitial Lung Disease (ILD)

    phase 1 mab active

    1 trial

  25. Human Umbilical Mesenchymal Stem Cells

    The First People's Hospital of Lianyungang

    Osteoarthritis, Knee

    phase 1 mab active

    1 trial

  26. Human amniotic epithelial stem cells（hAESCs）

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Graft Versus Host Disease

    phase 1 mab terminated

    1 trial

  27. Human amniotic-derived mesenchymal stem cells

    The First People's Hospital of Lianyungang

    Chronic Kidney Diseases

    phase 1 mab active

    1 trial

  28. Human butyrylcholinesterase (HuBChE) derived from human plasma

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  29. Human interferon alfa 1b inhalation solution

    United Therapeutics Europe Ltd

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  30. Human umbilical cord mesenchymal stem cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pneumoconiosis

    phase 1 mab active

    1 trial

  31. Humanized TNFα monoclonal antibody

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Rheumatoid Arthritis

    phase 1 small molecule completed

    1 trial

  32. Humanized anti-CD117 Monoclonal Antibody (JSP191)

    Jasper Therapeutics

    MYELODYSPLASTIC SYNDROME; MDS

    phase 1 mab active

    1 trial

  33. Hutrukin

    XBiotech Germany GmbH

    Pharmacokinetics

    phase 1 mab completed

    1 trial

  34. Hydrocodone Bitartrate

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule active

    1 trial

  35. Hydrocodone Bitartrate extended-release tablet

    Teva Pharma GmbH

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  36. Hydrocodone bitartrate extended-release tablet

    Teva Pharma GmbH

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  37. Hydrocortisone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule active

    1 trial

  38. Hydrocortisone granules

    NEUROCRINE BIOSCIENCES INC

    Adrenal Insufficiency

    phase 1 small molecule completed

    1 trial

  39. Hydromorphone

    Grace Therapeutics

    Pain

    phase 1 small molecule completed

    1 trial

  40. Hydromorphone 16 mg

    Janssen Cilag International NV

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  41. Hydronidone capsules

    The First People's Hospital of Lianyungang

    Liver Fibrosis

    phase 1 small molecule active

    1 trial

  42. Hyperpolarized xenon

    United Therapeutics Europe Ltd

    Lung Disease

    phase 1 small molecule completed

    1 trial

  43. I-131-CLR1404

    Cellectar Biosciences

    Cancer

    phase 1 small molecule completed

    1 trial

  44. I-131-CLR1404

    Cellectar Biosciences

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  45. I-131-CLR1404

    Cellectar Biosciences

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  46. I124-NM404

    Cellectar Biosciences

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  47. IASO104

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Relapsed/Refractory Multiple Myeloma (RRMM)

    phase 1 mab active

    1 trial

  48. IASO206 injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Autoimmune Hemolytic Anemia

    phase 1 mab active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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