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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. Four naloxone nasal spray doses (1 every 2.5 min)

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  2. Freethiadine tablets(part I)

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Hepatitis B, Chronic

    phase 1 small molecule completed

    1 trial

  3. Fucoidan (extract of Laminaria japonica)

    Takeda

    Healthy Volunteers

    phase 1 other completed

    1 trial

  4. Furmonertinib

    ArriVent BioPharma

    Non-Small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial

  5. G207

    BRIGHT MINDS BIOSCIENCES INC.

    Supratentorial Neoplasms, Malignant

    phase 1 mab completed

    1 trial

  6. GB-0669

    Generate Biomedicines

    SARS CoV-2

    phase 1 small molecule completed

    1 trial

  7. GB-0895 (SC)

    Generate Biomedicines

    Asthma

    phase 1 mab active

    1 trial

  8. GB-4362

    Generate Biomedicines

    Advanced Urothelial Cancer

    phase 1 small molecule active

    1 trial

  9. GB-5267 - IV only

    Generate Biomedicines

    Platinum-resistant Ovarian Cancer

    phase 1 mab active

    1 trial

  10. GB-7624

    Generate Biomedicines

    Atopic Dermatitis (AD)

    phase 1 small molecule active

    1 trial

  11. GBR 12909

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 1 small molecule active

    3 trials

  12. GC012F Injection infusion

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Idiopathic Inflammatory Myopathy (IIM)

    phase 1 small molecule active

    1 trial

  13. GC1102

    Green Valley (Shanghai) Pharmaceuticals Co.,

    Hepatitis B

    phase 1 mab completed

    1 trial

  14. GC4419

    Galera Therapeutics

    Squamous Cell Carcinoma of the Oral Cavity

    phase 1 small molecule completed

    1 trial

  15. GC4419

    Galera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  16. GC4419

    Galera Therapeutics

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  17. GC4419 IV

    Galera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  18. GC4702 dry powder

    Galera Therapeutics

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  19. GC4711 30 mg IV

    Galera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  20. GC4711 30mg

    Galera Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  21. GC4711 Oral Capsule G-101

    Galera Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  22. GCAR1

    Chongqing Precision Biotech Co., Ltd

    Sarcoma

    phase 1 mab active

    1 trial

  23. GCC2005

    Artiva Biotherapeutics

    Lymphoma, T-Cell

    phase 1 small molecule active

    1 trial

  24. GCPGC, Neulasta, Placebo

    Hospital Authority, Hong Kong

    Healthy

    phase 1 small molecule completed

    1 trial

  25. GDC-0084

    KAZIA THERAPEUTICS LTD

    Brain and Central Nervous System Tumors

    phase 1 small molecule completed

    1 trial

  26. GDC-0084

    KAZIA THERAPEUTICS LTD

    Brain Metastases

    phase 1 small molecule active

    1 trial

  27. GEN1042

    Genmab A/S

    Malignant Solid Tumor

    phase 1 mab active

    1 trial

  28. GHB01L1

    Atea Pharmaceuticals

    Seasonal Human Influenza

    phase 1 mab completed

    1 trial

  29. GHB04L1

    Atea Pharmaceuticals

    Influenza, Avian

    phase 1 mab completed

    1 trial

  30. GHB04L1

    Atea Pharmaceuticals

    Influenza

    phase 1 mab completed

    1 trial

  31. GK01 Injection

    The First People's Hospital of Lianyungang

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  32. GLA-AF

    Lxo Ireland Designated Activity Company

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  33. GLA-SE

    Lxo Ireland Designated Activity Company

    Merkel Cell Carcinoma

    phase 1 mab completed

    1 trial

  34. GLPG0187

    Lakefront Biotherapeutics NV

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  35. GLPG0187

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  36. GLPG0187 prodrug

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  37. GLPG0259

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  38. GLPG0259 fumarate

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  39. GLPG0259 solution

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  40. GLPG0492

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    3 trials

  41. GLPG0555

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    2 trials

  42. GLPG0555 solid dispersion

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  43. GLPG0634

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    3 trials

  44. GLPG0634

    Lakefront Biotherapeutics NV

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  45. GLPG0634 100mg capsule once a day for 10 days

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  46. GLPG0634 50 mg

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    1 trial

  47. GLPG0634, Jyseleca 200 mg film-coated tablets, Jyseleca 100 mg film-coated tablets

    Alfasigma S.p.A.

    juvenile idiopathic arthritis

    phase 1 small molecule active

    1 trial

  48. GLPG0778

    Lakefront Biotherapeutics NV

    Healthy

    phase 1 small molecule completed

    2 trials

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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