Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10799559

    NOPE for treatment of pathological muscle loss and weakness

    Five Prime Therapeutics, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10799549

    Hepatoprotective traditional chinese medicine composition containing fructus ligustri lucidi, herba exliptae, radix paeoniae alba, rhizoma curcumae longae and clam extract, preparation method and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10799535

    Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10799561

    Method for increasing cardiac inflow by administering a compound that binds RXFP1

    Relaxera Pharmazeutische Gesellschaft mbH & Co. KG · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10799514

    Non-hormonal steroid modulators of NF-kappa beta for treatment of disease

    ReveraGen BioPharma, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10799511

    Methods for reducing or ameliorating mortality and/or morbidity due to chlorine inhalation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10799512

    Estrogen combination for treatment of multiple sclerosis

    The Regents of the University of California · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10799520

    Lipotechoic acid for immune modulation

    Northwestern University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10799490

    Pharmaceutical compositions of therapeutically active compounds

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10799573

    Pertussis vaccines and methods of making and using

    Regents of the University of Minnesota · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10800781

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10799472

    Antiparasitic compositions and methods

    TYRATECH, INC. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10799466

    Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief

    The Board of Regents of the University of Texas System · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10799475

    Substituted phenyl aziridine precursor analogs for inhibiting androgen-independent prostate cancer cell growth

    Northwestern University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10798955

    Compositions of particulate coformulation

    Nektar Therapeutics · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10799092

    System and method for cleansing segments of a luminal network

    Covidien LP · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10799567

    Yeast-based immunotherapy and type I interferon sensitivity

    The Regents of the University of Colorado · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10799525

    Composition of novel carbohydrate drug for treatment of human diseases

    GALECTIN THERAPEUTICS, INC. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10799485

    Methods and compositions for treatment of epileptic disorders

    OVID THERAPEUTICS INC. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10799468

    Methods and compositions for treating conditions associated with an abnormal inflammatory responses

    First Wave Bio, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10799461

    Methods for targeted in vitro and in vivo drug delivery to mammalian cells via bacterially derived intact minicells

    EnGeneIC Molecular Delivery Pty Ltd · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10800813

    Modulation of structured polypeptide specificity

    BicycleRD Limited · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10800833

    Co-stimulatory domains for use in genetically-modified cells

    Precision BioSciences, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10800854

    Chimeric cytokine receptors and encoding nucleic acids

    AUTOLUS LIMITED · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10800769

    Heterocyclic inhibitors of ATR kinase

    The Board of Regents of the University of Texas System · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10799596

    Pyrrolobenzodiazepine-antibody conjugates

    ADC THERAPEUTICS SA · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10801076

    Influenza A virus variants

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10800855

    Chimeric cytokine receptors and encoding nucleic acids

    AUTOLUS LIMITED · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10808004

    Triterpene-glycoside as sweetener or sweetener enhancer

    Analyticon Discovery GmbH · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10808246

    Oligonucleotide-ligand conjugates and process for their preparation

    Alnylam Pharmaceuticals, Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10809323

    Magnetic resonance maps for analyzing tissue

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10806763

    Compositions of polymeric myrcene

    REGENERA PHARMA LTD. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10808011

    Recombinant HIV-1 envelope proteins and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10806742

    Liquid phospholipid-containing compositions for the preparation of pharmaceuticals

    AKER BIOMARINE ANTARCTIC AS · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10806740

    Natural combination hormone replacement formulations and therapies

    Compass Therapeutics LLC · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10806700

    Oral dosage forms for delivery of therapeutic agents

    Covidien LP · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10806697

    Vaginal inserted estradiol pharmaceutical compositions and methods

    Compass Therapeutics LLC · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10806716

    Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity

    Auransa Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10806750

    RNAi therapy for hepatitis B virus infection

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10806782

    Hand, foot, and mouth vaccines and methods of manufacture and use thereof

    Takeda Vaccines, Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10808010

    Peptide inhibitors of phosphoglycerate mutase and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10808247

    Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach

    Phio Pharmaceuticals Corp. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10808230

    Selection methods for genetically-modified T cells

    The Board of Regents of the University of Texas System · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10807987

    Heterocyclic compound and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10808225

    Use of PDL1 expressing cells to convert T cells into regulatory T cells

    The Government of the United States of American, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10806730

    Methods of treating cancer with farnesyltransferase inhibitors

    Kura Oncology, Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10806702

    Bis-polymer lipid-peptide conjugates and nanoparticles thereof

    The Regents of the University of California · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10806781

    Compositions and methods for live, attenuated alphavirus formulations

    Takeda Vaccines, Inc. · Granted Tue Oct 20 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 15 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.