Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10870652

    Compounds and methods for modulating bruton's tyrosine kinase

    Corvus Pharmaceuticals, Inc. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10870632

    Process for producing an extract containing tetrahydrocannabinol and cannabidiol from cannabis plant material, and cannabis extracts

    BIONORICA ETHICS GMBH · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10869948

    Composition of collagen peptide and elastin peptide, method of producing the same and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10869933

    Oligomer-phenothiazine conjugates

    Nektar Therapeutics · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10869880

    Methods for treating NLRP3 inflammasome-associated diseases, and methods of identifying agents useful therefor

    The Regents of the University of California · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10869866

    Benzathine analogs

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10869871

    Compositions and methods of modulating short-chain dehydrogenase activity

    The Board of Regents of the University of Texas System · Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. EP 3752616

    ZUSAMMENSETZUNGEN UND VERFAHREN ZUR GENEDITIERUNG DURCH TARGETING VON FIBRINOGEN-ALPHA

    CRISPR THERAPEUTICS AG [CH] · Granted Wed Dec 23 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Dec 18 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. LT 3254695

    COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER

    ASTELLAS PHARMA INC [JP] · Granted Mon Dec 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Sun Dec 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10874743

    IRAK degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10874676

    Methods for treating subjects with Prader-Willi syndrome or Smith-Magenis syndrome

    ESSENTIALIS, INC. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10875894

    Multimeric bicyclic peptide ligands

    BicycleTx Limited · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10876114

    Methods and means for efficient skipping of at least one of the following exons of the human Duchenne muscular dystrophy gene: 43, 46, 50-53

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10874609

    ß-cyclodextrin-based star-shaped polymer, a preparation method therefor and an integrated unimolecular micelle system for diagnosis and treatment thereof

    South China University of Technology · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10874633

    Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity

    Auransa Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10874649

    2-spiro-5- and 6-hydroxamic acid indanes as HDAC inhibitors

    Valo Early Discovery, Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10874673

    Inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10874709

    Conjugate of salicylic acid and peptide

    CAREGEN CO., LTD. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10874748

    Intervention for tendinopathy

    Montefiore Medical Center · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10875907

    Filovirus antibody

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10875911

    High affinity human antibodies to human angiopoietin-2

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10875913

    Methods of treatment using activatable anti-EGFR antibodies

    CytomX Therapeutics, Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10875920

    Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10876118

    Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell

    The Regents of the University of California · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10874092

    Humanized skeletal muscle

    Regents of the University of Minnesota · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10874622

    Dual assembly nanoparticles

    The Board of Regents of the University of Texas System · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10874610

    Extracellular vesicle-based diagnostics and engineered exosomes for targeted therapeutics against cancer

    Northwestern University · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10874334

    Methods and systems for quantification of blood-brain barrier permeation of glycosylated peptides

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10874631

    Altertoxin II as a selective inhibitor of Ewing family of tumor cells

    The Board of Regents of the University of Texas System · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10874648

    Methods for the administration of certain VMAT2 inhibitors

    Neurocrine Biosciences, Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10874635

    Tocotrienol compositions

    First Tech International Limited · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10874643

    5HT agonists for treating disorders

    The Regents of the University of California · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10874638

    Methods and compositions for modulating hormone levels

    Ligand Pharmaceuticals Incorporated · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10874659

    Iloperidone metabolite for use in the treatment of psychiatric disorders

    VANDA PHARMACEUTICALS INC. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10874672

    Methods for treating Huntington's disease

    PTC THERAPEUTICS, INC. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10874678

    Selective high-affinity polydentate ligands and methods of making such

    The Regents of the University of California · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10875855

    Inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10875915

    Anti-CXCR5 antibodies and compositions and uses thereof

    The Regents of the University of California · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10874745

    Antimicrobial peptides and methods of treating gram-negative pathogens: polar and non-polar face analogs

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10874719

    Nucleotide phosphate dissipation as a treatment for vascular disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10874727

    Inducible regulatory t-cell generation for hematopoietic transplants

    Regents of the University of Minnesota · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10875839

    Somatostatin modulators and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10874840

    Preparation comprising exanatide for delivery into a lumen of the intestinal tract

    Rani Therapeutics, LLC · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10874768

    Drug eluting medical device

    Covidien LP · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10874752

    MIBG analogs and uses thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10875885

    β-d-2′-deoxy-2′-α-fluoro-2′-β-c-substituted-2-modified-n6-substituted purine nucleotides for HCV treatment

    Atea Pharmaceuticals, Inc. · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10875860

    Azaindenoisoquinoline compounds and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10875903

    Bifunctional fusion proteins to inhibit angiogenesis in tumor microenvironment and to activate adaptive immune responses and the genes and uses thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Dec 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.