Monday, July 20, 2026

P0 · Patent assignees

Most active patent assignees

Pharmaceutical companies ranked by USPTO patent portfolio size and near-term expirations.

Quick answer

The most active pharmaceutical patent assignees in our USPTO index include Teva Pharma, Axsome Therapeutics, United Therapeutics Europe — ranked by total granted patents with 24-month expiration counts for patent-cliff planning.

Rank Assignee Patents Expiring ≤24m
1 Teva Pharma 185 22
2 Axsome Therapeutics 156 0
3 United Therapeutics Europe 90 5
4 Takeda 90 3
5 Vertex Pharmaceuticals (Australia) 57 0
6 Vanda Pharmaceuticals Netherlands 56 0
7 Regeneron Ireland Designated 50 1
8 Regeneron UK 48 0
9 Compass Therapeutics 43 0
10 Jazz Pharmaceuticals Ireland 36 0
11 SUPERNUS PHARMACEUTICALS 34 0
12 Alnylam Netherlands 34 0
13 CORCEPT THERAPEUTICS 33 0
14 Heron Therapeutics 33 0
15 Pacira Ireland 27 0
16 NEUROCRINE BIOSCIENCES 27 0
17 Coherus Oncology 27 0
18 Indivior Pty 26 0
19 Arcutis Biotherapeutics 25 0
20 Agios Netherlands 24 0
21 ALMIRALL S.P.A 22 0
22 Cumberland Pharmaceuticals 20 0
23 Amneal Pharma Europe 19 0
24 BioXcel Therapeutics 17 0
25 Tonix Pharmaceuticals Holding 16 0
26 Acadia Pharmaceuticals 16 0
27 AB Science 15 0
28 HALOZYME THERAPEUTICS 14 0
29 RIGEL PHARMACEUTICALS 14 0
30 Karyopharm Therapeutics 13 0
31 BioMarin Pharmaceutical Australia 12 0
32 Biocryst 12 0
33 RedHill Biopharma 11 0
34 Akebia Europe 11 0
35 Theravance Biopharma Ireland 11 1
36 Esperion Therapeutics 11 1
37 MAIA Biotechnology 9 0
38 Crinetics Pharmaceuticals Europe 9 0
39 Genzyme Europe 9 0
40 Tarsus Pharmaceuticals 8 0
41 LEXICON PHARMACEUTICALS 8 0
42 FENNEC PHARMACEUTICALS 8 0
43 Kalvista Pharmaceuticals (Ireland) 8 0
44 COLLEGIUM PHARMACEUTICAL 8 0
45 Vera Therapeutics 7 0
46 Verrica Pharmaceuticals 7 0
47 IRONWOOD PHARMACEUTICALS 6 0
48 IONIS PHARMACEUTICALS 6 0
49 Evofem Biosciences 6 0
50 Disc Medicine 6 0

Frequently asked questions

How are assignees ranked?

By count of published pharmaceutical patents (A61K/A61P) where the company matches USPTO assignee to our company directory.

Where do I see the full portfolio?

Each assignee links to a dedicated company patent hub with pagination, expiring filters, and drug cross-links.