Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10780133

    Method for protecting liver and a liver protecting agent

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 10780136

    Reduction of milk glycans and their degradation products in the neonate gut

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 10780154

    Salmonella paratyphi A with an O-antigen having an extended carbohydrate chain and use thereof

    Institute of Biotechnology, Academy of Military Medical Sciences, China · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 10780165

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 10780163

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 10780145

    In situ forming hydrogel and method using same

    ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 10780147

    Vault complexes for cytokine delivery

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 10781169

    Method of synthesis of an ionizable cationic lipid

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 10781181

    N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors

    KalVista Pharmaceuticals Limited · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 10781183

    Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 10780185

    Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 10781450

    Antisense molecules and methods for treating pathologies

    Sarepta Therapeutics, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 10781422

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 10781242

    Interleukin-2 fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 10781251

    Monoclonal antibodies to growth and differentiation factor 15 (GDF-15)

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 10781255

    Anti-CD83 antibodies and use thereof

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10781435

    Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use

    Catalyst Biosciences, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10786566

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10786554

    Factor VIII polypeptide formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10787452

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 10785968

    Genetically modified non-human animals and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 10786520

    Aminoglycoside derivatives and uses thereof in treating genetic disorders

    ELOXX PHARMACEUTICALS LTD. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 10786552

    Il-2Rβ-selective agonists in combination with an anti-CTLA-4 antibody or an anti-PD-1 antibody

    Nektar Therapeutics · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 10787413

    Derivatives of curcuminoids and use thereof as an anticancer agent

    China Medical University · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 10787490

    Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases

    Protagonist Therapeutics, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 10786582

    Gd(III)-dithiolane gold nanoparticle conjugates

    Northwestern University · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 10787472

    Prodrugs of pyridone amides useful as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 10788490

    Dried cellulose-treated tissue for in-vitro complement activation assays and diagnostic kits

    ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 10786545

    Use of peptides that block metadherin-SND1 interaction as treatment for cancer

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 10787462

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 10787449

    Octahydro fused azadecalin glucocorticoid receptor modulators

    Corcept Therapeutics Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 10787647

    HSD17B13 variants and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 10787499

    EpCAM targeted polypeptides, conjugates thereof, and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 10787501

    Anti-SARS-CoV-2-spike glycoprotein antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 10787439

    Compounds and methods for activating the apoptotic arm of the unfolded protein response

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 10787419

    Cannabinoid receptor mediating iminopyrazole compounds

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 10786501

    Treatment of prostate cancer

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 10786435

    Composition for optical three-dimensional modeling

    KURARAY NORITAKE DENTAL INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 10786495

    Vesicular monoamine transporter 2 inhibitors for treating stuttering

    The Regents of the University of California · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 10785966

    Humanized M-CSF mice

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 10786438

    Recombinant nucleic acids encoding cosmetic protein(s) for aesthetic applications

    Krystal Biotech, Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 10787446

    Therapeutic compounds and methods of use thereof

    Xenon Pharmaceuticals Inc. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 10786461

    Onapristone extended-release compositions and methods

    CONTEXT BIOPHARMA, INC. · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 10786512

    DNA-PK inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 29 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 24 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. CA 3133787

    GELS HOMOGENES INJECTABLES COMPRENANT DE MULTIPLES FORMES D'ACIDE HYALURONIQUE ET LEURS PROCEDES DE FABRICATION

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Oct 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 26 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 10792370

    Antibody-drug conjugate

    SHANGHAI MIRACOGEN INC. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 10793595

    Toll-like receptor 2 ligands and methods of making and using thereof

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 10793564

    Amino acid compounds and methods of use

    Pliant Therapeutics, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.