Tuesday, July 21, 2026

Intelligence · Patents

Expiring patents (≤24 months)

Patent cliff watchlist — pharmaceutical patents approaching loss of exclusivity.

Patents
34

Quick answer

34 pharmaceutical patents in our index expire within the next 24 months. Use year facets below for annual patent-cliff planning linked to company and drug profiles.

  1. US 7087591

    21-substituted progesterone derivatives as new antiprogestational agents

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Aug 08 2006 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 03 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 7122624

    Parathyroid hormone receptor ligands

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Oct 17 2006 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 12 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 7126008

    Carvedilol

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Oct 24 2006 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 19 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 7138137

    Stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Nov 21 2006 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 16 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 7148376

    Polymorphic forms of nateglinide

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Dec 12 2006 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 07 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 7183272

    Crystal forms of oxcarbazepine and processes for their preparation

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 27 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 22 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 7196222

    Sertraline hydrochloride form II and methods for the preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Mar 27 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 22 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 7196205

    Synthesis of UDP-glucose: N-acylsphingosine glucosyltransferase inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 27 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 22 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 7199157

    Use of treprostinil to improve kidney functions

    United Therapeutics Corporation · Granted Tue Apr 03 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 29 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 7235691

    Crystalline forms of modafinil

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jun 26 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 21 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 7247751

    Processes for preparing cinacalcet hydrochloride crystal Form I

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 24 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 19 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 7256195

    Preparation of risperidone

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Aug 14 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 09 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 7262218

    Forms of pravastatin sodium

    TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG · Granted Tue Aug 28 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 23 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 7285668

    Process for the crystallization of (R)- or (S)-lansoprazole

    Takeda Pharmaceutical Company Limited · Granted Tue Oct 23 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 18 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 7288657

    Biphenyl compounds useful as muscarinic receptor antagonists

    Theravance, Inc. · Granted Tue Oct 30 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 25 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 7300935

    Thienopyrimidine compounds and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Nov 27 2007 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 22 2027 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 7319171

    Sertraline hydrochloride form II and methods for the preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jan 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 7320991

    Analogs of thalidomide as potential angiogenesis inhibitors

    The United States of America as Represented by The Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer · Granted Tue Jan 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 7323459

    Crystal forms, methods for their preparation and method for preparation of olanzapine

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jan 29 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 24 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 7332472

    Cyclosporine analogue mixtures and their use as immunomodulating agents

    Isotechnika, Inc. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 7332612

    Amorphous and crystalline forms of losartan potassium and process for their preparation

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Feb 19 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 14 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 7335799

    Hydroxyl compounds and compositions for cholesterol management and related uses

    Esperion Therapeutics, Inc. · Granted Tue Feb 26 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 21 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 7348429

    Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide(zaleplon) and crystalline forms of zaleplon accessible with the process

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Mar 25 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 20 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 7357945

    Stable pharmaceutical formulation of paroxetine hydrochloride and a process for preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 7358390

    Polymorphic forms of nateglinide

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 7358360

    Risedronate sodium having a very low content of iron

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 7358247

    Mycophenolate mofetil impurity

    TEVA Gyógyszergyár Zártkörüen Müködö Részvénytárasaság · Granted Tue Apr 15 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 10 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 7361664

    Vitamin D receptor antagonists and related compositions and methods of use

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Apr 22 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 17 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 7368468

    Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue May 06 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 7368606

    Amorphous cinacalcet hydrochloride and preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue May 06 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 01 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 7378108

    Percutaneous absorption preparation of compound having angiotensin II antagonistic activity

    Takeda Pharmaceutical Company Limited · Granted Tue May 27 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 22 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 7390807

    Crystal forms of lamotrigine and processes for their preparations

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jun 24 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 19 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 7396542

    Stable pharmaceutical formulation of paroxetine hydrochloride anhydrous and a process for preparation thereof

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 7396860

    Use of rasagiline with or without riluzole to treat amyotrophic lateral sclerosis

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Jul 08 2008 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 03 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

What is a patent cliff?

A patent cliff is when key pharmaceutical patents expire, opening markets to generics or biosimilars. This hub lists USPTO patents with approaching expiration dates.

Are expiration dates estimates?

Expiration dates derive from USPTO PatentsView grant dates and term estimates. Confirm with Orange Book, patent counsel, and USPTO records before investment decisions.