CRO & Clinical Services

4D Pharma develops Live Biotherapeutics, a novel class of drugs defined by the FDA as biological products containing live organisms like bacteria for preventing, treating, or curing diseases. The company uses its proprietary MicroRx platform to identify single-strain, naturally occurring gut bacteria candidates for oncology, respiratory, gastrointestinal, CNS, and autoimmune diseases. Clinical programs include trials in pancreatic cancer, asthma, COVID-19, and IBS, with manufacturing in Spain and collaborations like MSD for vaccines.

Informuta develops precision diagnostics for drug-resistant infections using machine learning and DNA sequencing technology. The company's RESISENSE platform forecasts treatment-emergent antibiotic resistance before it occurs, enabling clinicians to select optimal therapies on a patient-by-patient basis. Informuta's technology helps prevent treatment failures, reduce antibiotic misuse, and strengthen antimicrobial stewardship in hospital settings.

ATCC is the premier global biological materials resource, offering the world's largest and most diverse collection of authenticated cell lines, microorganisms, and molecular genomic tools for pharmaceutical research, development, and quality control. Products are manufactured under ISO 9001:2008 certification and ISO/IEC 17025:2005 accreditation, with custom services for developing, characterizing, manufacturing, storing, and supplying cell lines and microbes. They support pharmaceutical, biotech, vaccine manufacturers, and regulatory agencies worldwide through direct shipping and distributors in over 140 countries.

TESCAN GROUP provides advanced scanning electron microscopes (SEM), focused ion beam SEM (FIB-SEM), transmission electron microscopes (TEM), and micro-CT systems for life sciences and pharmaceutical R&D. These instruments support high-resolution imaging, 3D analysis, and material characterization in biological and pharmaceutical research applications. With installations worldwide, TESCAN enables non-destructive internal analysis and dynamic imaging for drug development and biomaterial studies.

ACROBiosystems provides recombinant proteins, antibodies, reagents, and analytical testing services to accelerate biological drug development from research to clinical applications. They offer GMP-grade cell culture materials, growth factors, and solutions for cell and gene therapy, supported by in-house protein engineering platforms and ISO 9001/13485/17025-certified labs. With global presence across 14 locations and over 800 employees, they focus on innovation in biopharmaceuticals, immunotherapies, and precision medicine.

Acros Organics, now part of Thermo Scientific Chemicals, provides high-purity organics, fine chemicals, building blocks, and ultra-pure inorganics for pharmaceutical R&D and synthesis. Their portfolio includes over 33,000 products with trace metal content as low as 1 ppm, supporting applications in catalysis, crystal growth, and high-tech manufacturing. They offer custom and bulk chemicals, specialized testing, and tailored packaging for life sciences and pharma needs.

Indero is a dual-focus contract research organization (CRO) specializing in dermatology and rheumatology clinical trials, offering end-to-end services from early to late phase. Services include patient recruitment, medical monitoring, and innovative methods like quantitative gene expression for topical drug evaluation. They also support aesthetics and cosmetics trials with global reach and therapeutic expertise.

Aria Pharmaceuticals is a preclinical-stage company developing novel small molecule therapies for complex diseases including lupus, idiopathic pulmonary fibrosis (IPF), chronic kidney disease (CKD), and non-alcoholic steatohepatitis (NASH). It employs a proprietary AI platform that integrates 25 data sources and over 65 methods to identify high-efficacy candidates, achieving a 30-fold higher success rate in animal efficacy studies compared to traditional approaches. The company has filed provisional patents for lead candidates like TXR-711 (lupus), TXR-1002 (IPF), and TXR-1210 (CKD), with plans to advance into IND-enabling studies.

Arrayjet provides custom microarray services for pharmaceutical R&D, including assay development, high-throughput screening, and contract manufacturing using their patented inkjet bioprinting platform. They support applications such as DNA/RNA microarrays, protein microarrays, genotyping, transcriptomics, SNP analysis, epitope mapping, and drug discovery. Services include full sample preparation, quality checks, data extraction, bioinformatics, and global shipping with complex requirements, delivered within 1-2 weeks.

Arrayjet manufactures high-throughput inkjet microarray printers and provides custom microarray services for pharma, biotech, and diagnostics. Their patented technology supports applications including antibody characterization, biomarker discovery, drug screening, and gene expression profiling. Operations are based in an ISO13485:2016 accredited facility in Edinburgh, Scotland, enabling scalable solutions from research to commercial manufacture.

Asahi Kasei Bioprocess, under Asahi Kasei Life Science established in April 2025, provides virus removal filters like Planova™ and Microfilters BioOptimal™, along with CRO testing services via ViruSure and Bionique, and CDMO services through Bionova Scientific. These solutions support viral safety in cell culture media, downstream biopharmaceutical manufacturing, and emerging biologics modalities. The company is expanding Planova™ production capacity with a new facility in Japan starting operations in 2030 to meet global demand.

CARB-X is a global non-profit partnership that accelerates the development of antibacterial products to combat drug-resistant bacteria. The organization provides non-dilutive funding, scientific expertise, regulatory guidance, and business support to developers of new antibiotics, preventatives, rapid diagnostics, and related products. CARB-X maintains the world's most scientifically diverse early-stage pipeline, supporting projects from basic research through Phase 1 clinical trials and prototype development.

Cayman Chemical is a US-based CRO and CDMO offering chemistry and biology services to pharmaceutical, biotechnology, and academic markets. They provide custom chemical synthesis, medicinal chemistry, bioanalysis, assay development, and preclinical drug discovery support including psychedelics. Additional offerings include high-purity biochemicals, assay kits, antibodies, recombinant proteins, and cGMP manufacturing across US and EU facilities.

CellarisBio offers the MICRO-TAG® platform, a reagent-based technology that quantifies ligand-target engagement in real-time within intact live cells, preserving native protein context. It supports drug discovery for challenging targets like degraders, molecular glues, and covalent inhibitors by providing quantitative fluorescent readouts compatible with standard workflows. Based in San Diego, California, the company delivers reagents and collaborative solutions for precision therapeutic development.

Cencora PharmaLex provides specialized consulting services for pharmaceutical, biotech, and medtech industries, guiding clients from early strategic planning through clinical development, regulatory submissions, and post-launch activities. The company offers expertise in pharmacovigilance, quality management, compliance, and clinical regulatory support across the product lifecycle. As part of Cencora, PharmaLex delivers global solutions with technology-enhanced processes for regulatory affairs and patient safety.

AnalytiChem UK (formerly Cherwell Laboratories) manufactures and supplies cleanroom microbiology solutions, including Redipor® prepared media, for environmental monitoring, operator validation, and sterilisation process validation in pharmaceutical and biotech industries. The company offers microbial air samplers, biological indicators, and bespoke products for GMP-compliant controlled environments from its Bicester, UK facility. Products support pharmaceutical manufacturing, pharmacy compounding, and healthcare applications across the UK and Europe.

Crown Bioscience is a global contract research organization providing integrated biomarker services, preclinical models, and translational platforms for pharmaceutical and biotechnology companies. The company offers tissue-based analysis, genomics, proteomics, and comprehensive bioinformatics services across in vivo, in vitro, ex vivo, and in silico platforms. Crown operates over 800 organoid models and 2,700 PDX models enhanced by biomarker analysis, supporting drug efficacy assessment and pharmacological profiling from discovery through clinical trial readiness.

Cyagen Biosciences specializes in custom genetically engineered mouse and rat models, including knockout, knockin, conditional knockout, transgenic, and Cre-recombinase strains for genetics, pharmacology, and disease modeling research. They offer integrated preclinical services such as cell and animal model development, viral packaging, and expert-led studies to support drug discovery, validation, and IND applications. Additional products include stem cells like OriCell™ bone marrow mesenchymal stem cells and AAV solutions for gene therapy.

Cyprotex provides specialized ADME-Tox services, including in vitro screening, mechanistic toxicology, high content 3D tissue analysis, and pharmacokinetic predictions via Cloe PK. They support drug discovery from early stages to regulatory submission with high-throughput assays, immunotoxicology, gene therapy capabilities, and AI-driven data generation. As part of Evotec, Cyprotex delivers rapid turnaround times of 5-10 working days for standard screens using validated in vitro and in silico methods.

DEBRA Research, the research arm of DEBRA Austria, funds and advances translational research and clinical development for Epidermolysis Bullosa (EB) therapies. They build critical infrastructure including patient registries, biobanks, disease models, and clinical trial networks to accelerate EB treatment innovation. As a non-profit, they collaborate globally with academia, biotech, pharma, and patient organizations to turn research into curable solutions for EB.

Dassault Systèmes provides an integrated digital platform for pharmaceutical and biotech companies spanning research, development, clinical trials, manufacturing, and commercialization. Their solutions leverage 3D visualization, simulation, and AI to accelerate drug development, optimize manufacturing processes, ensure regulatory compliance, and reduce time to market. The company acquired Medidata Solutions to enhance clinical data capabilities and support personalized medicine development.

Dolomite Microfluidics specializes in high-performance microfluidic systems for producing precision-engineered nano- and microparticles used in biomedicine, drug encapsulation, and delivery. Their platforms enable scalable droplet and particle generation with high monodispersity and batch consistency for pharmaceutical R&D. Key products include the Telos system for high-throughput processing and custom glass chips for applications like cell encapsulation and biological molecule separation.

o2h discovery is a Contract Research Organization providing integrated drug discovery services including hit identification, lead optimization, discovery chemistry, biology, and pharmacology. Operating from research centers in Cambridge, UK and Ahmedabad, India, the company supports clients through hit-lead-optimization programs leading to patent and IND filing with capabilities in fragment-based screening, custom synthesis, and computational chemistry.

Emulate provides Organ-on-a-Chip technology, including the Human Emulation System and AVA Emulation System, to model human organ functions like liver, kidney, and intestine for drug development and toxicology testing. These microfluidic platforms replicate human tissue responses more accurately than animal models, reducing R&D costs and translational failures. The company serves pharmaceutical, academic, and government researchers with validated chips for applications in cancer, immunology, and infectious diseases.