Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10792287

    Methods for treating mitochondrial diseases

    The Regents of the University of California · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10792368

    Bicyclic peptide ligands specific for MT1-MMP

    BicycleRD Limited · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10791731

    Methods for preparing frozen plasma material for rapid thawing in an emergency situation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10792481

    Implantable drug delivery device

    Nano Precision Medical, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10792251

    Liposomal particles, methods of making same and uses thereof

    Northwestern University · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10792274

    Dehydroacetic acid (DHAA) and derivative for uses in treating cancer

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10792370

    Antibody-drug conjugate

    SHANGHAI MIRACOGEN INC. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10793543

    Selective C-KIT kinase inhibitor

    HEFEI GRACEVO BIO-MEDICINE CO., LTD · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10792276

    Urolithins as immune response enhancers

    Amazentis SA · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10792282

    Protein kinase C inhibitors and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10792353

    Virus like particle purification

    Takeda Vaccines, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10792312

    Barrier layer

    ATRIUM MEDICAL CORPORATION · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10792363

    Anhydrous sodium thiosulfate and formulations thereof

    Fennec Pharmaceuticals, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10793482

    Compounds and compositions for delivery of nutrients and micronutrients to plants

    Spero Energy, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10793878

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10793865

    Transferrable mechanism of generating inducible, BAR domain protein-mediated bacterial outer membrane extensions

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10793862

    Compositions and methods for modulating growth hormone receptor expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10793884

    Methods and materials for making simvastatin and related compounds

    The Regents of the University of California · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10793846

    Compositions and methods for treating celiac sprue disease

    The Regents of the University of California · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10793636

    Anti-CD73 antibodies

    Corvus Pharmaceuticals, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10793624

    Human antibodies to Bet v 1 and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10793563

    GCN2 inhibitors and uses thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10793564

    Amino acid compounds and methods of use

    Pliant Therapeutics, Inc. · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10793595

    Toll-like receptor 2 ligands and methods of making and using thereof

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10793547

    Modulator of the cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 2020318108

    MATERIALS AND METHODS FOR TREATMENT OF USHER SYNDROME TYPE 2A AND/OR NON-SYNDROMIC AUTOSOMAL RECESSIVE RETINITIS PIGMENTOSA (ARRP)

    CRISPR THERAPEUTICS AG [CH] · Granted Thu Oct 08 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Oct 03 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10799596

    Pyrrolobenzodiazepine-antibody conjugates

    ADC THERAPEUTICS SA · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10798955

    Compositions of particulate coformulation

    Nektar Therapeutics · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10799475

    Substituted phenyl aziridine precursor analogs for inhibiting androgen-independent prostate cancer cell growth

    Northwestern University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10799466

    Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief

    The Board of Regents of the University of Texas System · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10799472

    Antiparasitic compositions and methods

    TYRATECH, INC. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10800781

    Compounds useful as inhibitors of ATR kinase

    Vertex Pharmaceuticals Incorporated · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10799490

    Pharmaceutical compositions of therapeutically active compounds

    Agios Pharmaceuticals, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10799520

    Lipotechoic acid for immune modulation

    Northwestern University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10799512

    Estrogen combination for treatment of multiple sclerosis

    The Regents of the University of California · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10799511

    Methods for reducing or ameliorating mortality and/or morbidity due to chlorine inhalation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10799514

    Non-hormonal steroid modulators of NF-kappa beta for treatment of disease

    ReveraGen BioPharma, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10799561

    Method for increasing cardiac inflow by administering a compound that binds RXFP1

    Relaxera Pharmazeutische Gesellschaft mbH & Co. KG · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10799535

    Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10799549

    Hepatoprotective traditional chinese medicine composition containing fructus ligustri lucidi, herba exliptae, radix paeoniae alba, rhizoma curcumae longae and clam extract, preparation method and use thereof

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10799559

    NOPE for treatment of pathological muscle loss and weakness

    Five Prime Therapeutics, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10799588

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10799580

    Expression vector delivery system and use thereof for inducing an immune response

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10799585

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10799576

    RSV vaccines and methods of production and use thereof

    The Board of Regents for Oklahoma State University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10799584

    Combination therapies using agents that target tumor-associated stroma or tumor cells and alkylating agents

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10799593

    Nanodiamond particle complexes

    Northwestern University · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10799590

    Compositions containing a bitter tastant and at least one sophorolipid, and methods of reducing bitter taste attributed to a bitter tastant in an edible composition

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Oct 13 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Oct 08 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.