Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10772897

    Method for on-demand contraception

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10774128

    IL-33 antagonists and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10774121

    Methods and compositions for treating neurodegenerative disorders and Alzheimer's Disease and improving normal memory

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10772942

    Lyophilized factor IX formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10772906

    Modulation of Factor 11 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10772924

    Therapeutic use of chardonnay seed products

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10774118

    Peptides having reduced toxicity that stimulate cholesterol efflux

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10774181

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10774083

    Heterocyclic amide compound

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10774066

    Prodrugs of NRF2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10772971

    Methods of producing drug-carrying polymer scaffolds and protein-polymer-drug conjugates

    Mersana Therapeutics, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10772963

    Etanercept formulations stabilized with xylitol

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10772960

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10772828

    Controlled release antimicrobial compositions and methods for the treatment of otic disorders

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10772854

    Methods and compositions for treating conditions associated with an abnormal inflammatory response

    First Wave Bio, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10772913

    Administration of kynurenine depleting enzymes for tumor therapy

    The Board of Regents of the University of Texas System · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10772972

    Anti-STEAP2 antibody drug conjugates, and compositions and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10774056

    Substituted piperazines as selective HDAC1,2 inhibitors

    Regenacy Pharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10774080

    Pyrimidine compound as JAK kinase inhibitor

    Theravance Biopharma R&D IP, LLC · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10774092

    ULK1 inhibitors and methods using same

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10774122

    ERG targeted therapy

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10774390

    Methods and compositions for modulating PrfA mediated virulence gene activation in Listeria spp

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10774344

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10772959

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10774333

    Modulators of PNPLA3 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10774334

    Regulated expression of antigen and/or regulated attenuation to enhance vaccine immunogenicity and/or safety

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10774330

    Reduced size self-delivering RNAI compounds

    Phio Pharmaceuticals Corp. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10774141

    Antibody for binding to interleukin 4 receptor

    SuZhou Connect Biopharmaceuticals, Inc. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10772956

    Methods for reducing or eliminating the need for lipoprotein apheresis in patients with hyperlipidemia by administering alirocumab

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 15 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 10 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. EP 3708579

    CLAUDIN-6-SPEZIFISCHE IMMUNREZPTOREN UND T-ZELL-EPITOPE

    BIONTECH CELL & GENE THERAPIES GMBH [DE] · Granted Wed Sep 16 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Sep 11 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10781181

    N-((het) arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors

    KalVista Pharmaceuticals Limited · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10781183

    Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10780185

    Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10781450

    Antisense molecules and methods for treating pathologies

    Sarepta Therapeutics, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10781422

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10781242

    Interleukin-2 fusion proteins and uses thereof

    Medicenna Therapeutics Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10781251

    Monoclonal antibodies to growth and differentiation factor 15 (GDF-15)

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10781255

    Anti-CD83 antibodies and use thereof

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10781435

    Modified membrane type serine protease 1 (MTSP-1) polypeptides and methods of use

    Catalyst Biosciences, Inc. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10781189

    1,2,4-Oxadiazole and thiadiazole compounds as immunomodulators

    Aurigene Discovery Technologies Limited · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10780058

    Nucleic acid nanocapsules for drug delivery and targeted gene knockdown

    UNIVERSITY OF CONNECTICUT · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10780067

    Endoxifen for local transdermal therapy to the breast

    Northwestern University · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10780095

    Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10780096

    Pyrrolobenzodiazepine-antibody conjugates

    ADC THERAPEUTICS SA · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10780155

    Streptococcal GlcNac-lacking gylcopolypeptides, cell wall carbohydrates, Streptococcus vaccines, and methods for making and using them

    The Regents of the University of California · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10781218

    Substituted inhibitors of menin-MLL and methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10780166

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10781208

    5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.