Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10829544

    Human antibodies to Ebola virus glycoprotein

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10829767

    Chimeric antigen receptors targeting B-cell maturation antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10829770

    Fusion proteins containing luciferase and a polypeptide of interest

    The Government of the United States of America, as represented by the Secretary of Homeland Security · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10829774

    Increasing levels of nicotinic alkaloids in plants

    22ND CENTURY LIMITED, LLC · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10829763

    TMPRSS6 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10829536

    Methods of promoting CNS neuronal repair by inhibiting LRP-1

    The Regents of the University of California · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10829550

    Polynucleotides encoding anti-CXCL13 antibodies

    VACCINEX, INC. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10829529

    Compositions and methods for delivering CFTR polypeptides

    Krystal Biotech, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10829518

    Peptide compositions and methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10829488

    N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10829486

    Isoxazole derivatives as FXR agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10829462

    3-alkyl bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors

    Valo Early Discovery, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10829460

    [6,6] fused bicyclic HDAC8 inhibitors

    Valo Early Discovery, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10829443

    Solvate form of (R)-2-amino-3-phenylpropyl carbamate

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10829464

    Benzoheterocyclic alkylamine compounds and use thereof

    East China University of Science and Technology · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10828376

    Liver-specific constructs and methods of use thereof

    Sangamo Therapeutics, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10828345

    Use of a VEGF antagonist to treat angiogenic eye disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10828414

    Magnetic filtration devices and methods related thereto

    The Regents of the University of California · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10830678

    Photo-controlled removal of targets in vitro and in vivo

    The United States of America, as represented by the Secretary, Department of Health and Human Serv · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10829427

    Naphthoquinones, pro-drugs, and methods of use thereof

    The Board of Regents of the University of Texas System · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10828326

    Compositions and methods for treating and preventing venom related poisoning

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10828315

    Targeted therapeutics

    Madrigal Pharmaceuticals, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10828301

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10828304

    Compositions and methods for white to beige adipogenesis

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10828289

    Hair follicle stem cell activation and hair growth

    The Regents of the University of California · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10828277

    Antioxidant complex for reducing number of somatic cell in livestock animal, and preparation method and application thereof

    China Agricultural University · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10828255

    Lipid bilayer coated mesoporous silica nanoparticles with a high loading capacity for one or more anticancer agents

    The Regents of the University of California · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10827969

    Breath test device and method

    EXALENZ BIOSCIENCE LTD. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10829769

    Chimeric antigen receptors targeting b-cell maturation antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10829461

    3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as HDAC inhibitors

    Valo Early Discovery, Inc. · Granted Tue Nov 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. CA 3135097

    COMBINAISON PHARMACEUTIQUE COMPRENANT DE LA TRAZODONE POUR LE TRAITEMENT DE LA DOULEUR NEUROPATHIQUE

    ACRAF [IT] · Granted Thu Nov 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 2020353106

    Stable, concentrated radionuclide complex solutions

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Nov 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Nov 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10835495

    Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same

    W.R. Grace & Co.-Conn. · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10835487

    Vaginal inserted estradiol pharmaceutical compositions and methods

    Compass Therapeutics LLC · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10836741

    Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors

    Valo Early Discovery, Inc. · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10836759

    Thiazole derivatives useful as mutant IDH1 inhibitors for treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10835549

    Polyplexes

    THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10836763

    5 to 7 membered heterocyclic amides as JAK inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10837003

    Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-utr of dengue types 1, 2, 3, and 4, or antigenic chimeric dengue viruses 1, 2, 3, and 4

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10837019

    Chimeric antigen receptors targeting B-cell maturation antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10835513

    Methods and treatments for the learning and memory deficits associated with Noonan syndrome

    The Regents of the University of California · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10835490

    Solid solution compositions and use in chronic inflammation

    Infirst Healthcare Limited · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10835593

    Modified anthrax toxin protective antigen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10835604

    Biomaterials for combined radiotherapy and immunotherapy of cancer

    Northwestern University · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10835755

    Method of using laser-induced optoacoustics for the treatment of drug-resistant microbial infections

    United States of America as represented by the Secretary of the Air Force · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10837961

    Molecular imprinted colored silica beads

    The Board of Regents of the University of Texas System · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10837016

    Modulation of huntingtin expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10836827

    Antibodies specific to glycosylated PD-L1 and methods of use thereof

    The Board of Regents of the University of Texas System · Granted Tue Nov 17 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Nov 12 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.