Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10752702

    Anti-TIE2 antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10751343

    Nasal compositions stimulating ciliary activity

    Veramed BV · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10752639

    Bridged bicyclic inhibitors of menin-MLL and methods of use

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10752920

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10751533

    Regulation of autonomic control of bladder voiding after a complete spinal cord injury

    The Regents of the University of California · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10751416

    IL-26 inhibitors

    The Board of Regents of the University of Texas System · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10751281

    Auris formulations for treating otic diseases and conditions

    The Regents of the University of California · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10752626

    Iso-citrate dehydrogenase (IDH) inhibitor

    SHANGHAI METON PHARMACEUTICAL CO., LTD · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10752681

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10758530

    Carboxamide derivatives useful as rsk inhibitors

    PHOENIX MOLECULAR DESIGNS · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10759721

    Deuterated CFTR potentiators

    Vertex Pharmaceuticals (Europe) Limited · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10758621

    Liquid formulation comprising GM-CSF neutralizing compound

    TAKEDA GMBH · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10758642

    Sterilization process

    Admedus Regen Pty Ltd. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10759759

    Prodrugs of kallikrein inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10758629

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10758632

    NIR-conjugated tumor-specific antibodies and uses thereof

    The Regents of the University of California · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10759795

    Aza-A-ring indenoisoquinoline topoisomerase I poisons

    United States Department of Health and Human Services · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10759791

    Mammalian and bacterial nitric oxide synthase inhibitors

    Northwestern University · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10759808

    Monofunctional intermediates for ligand-dependent target protein degradation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10759796

    CXCR4 inhibitors and uses thereof

    X4 Pharmaceuticals, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10759812

    Thienopyrimidine derivative and use thereof in medicine

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10759838

    Myelin oligodendrocyte glycoprotein, myelin basic protein, and proteolipid protein compositions and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10759839

    Cell-penetrating peptide

    NEOREGEN BIOTECH · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10759833

    VMP-like sequences of pathogenic Borrelia species and strains

    The Board of Regents of the University of Texas System · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10759816

    Heterocyclic compounds as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10759855

    Antigen binding molecules to TIGIT

    Rigel Pharmaceuticals, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10759863

    Modulation of γδ T cells

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10759906

    Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method

    Nektar Therapeutics · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10760048

    In vitro production of medial ganglionic eminence precursor cells

    The Regents of the University of California · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10760055

    Conditionally immortalized long-term stem cells and methods of making and using such cells

    The Regents of the University of Colorado · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10760078

    Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups

    Sarepta Therapeutics, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10759768

    Prophylactic or therapeutic agent for autism spectrum disorder

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10758496

    Estrogen receptor ligand treatment for neurodegenerative diseases

    The Regents of the University of California · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10758534

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10758513

    Modulators of mitochondrial protein import

    The Regents of the University of California · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10758526

    Combination therapies using agents that target tumor-associated stroma or tumor cells and other pathways

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10758618

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10758600

    Fungal immunogens and related materials and methods

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10758617

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10758613

    Combination therapies using anti-metabolites and agents that target tumor-associated stroma or tumor cells

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10758614

    Combination therapies targeting tumor-associated stroma or tumor cells and topoisomerase

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10758488

    Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances

    Jazz Pharmaceuticals, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10758511

    Stable analogs of CYP450 lipid metabolites and inhibitors of soluble epoxide hydrolase

    The Regents of the University of California · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10758595

    Treatment of retinitis pigmentosa using engineered meganucleases

    Precision BioSciences, Inc. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10758598

    TPP-1 formulations and methods for treating CLN2 disease

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10758619

    Controlled release mucoadhesive systems

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10759774

    Inhibitors of hepatitis B virus targeting capsid assembly

    Regents of the University of Minnesota · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10759793

    2-(pyrazolopyridin-3-yl)pyrimidine derivatives as JAK inhibitors

    Almirall, S.A. · Granted Tue Sep 01 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 27 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.