Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8449875

    Targeting pseudotyped retroviral vectors

    The Regents of the University of California · Granted Tue May 28 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8450481

    Compounds for inhibiting protein aggregation, and methods for making and using them

    The Regents of the University of California · Granted Tue May 28 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8450285

    Immunoregulatory peptides and methods of use

    Compass Therapeutics LLC · Granted Tue May 28 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8449872

    Polymer conjugates of nesiritide peptides

    Nektar Therapeutics · Granted Tue May 28 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8450055

    Malaria antigen screening method

    United States of America as represented by the Secretary of the Air Force · Granted Tue May 28 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 23 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8454946

    N-maleimidyl polymer derivatives

    Nektar Therapeutics · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8454965

    Method for the treatment of multiple sclerosis

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8455454

    miR 204, miR 211, their anti-miRs, and therapeutic uses of same

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8455499

    Alkyne antagonists of lysophosphatidic acid receptors

    AMIRA PHARMACEUTICALS, INC. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8455553

    Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease and transplant rejection

    The Regents of the University of California · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8455497

    Inhibitors of aspartyl protease

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8455652

    Inhibitors for the soluble epoxide hydrolase

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8454936

    Metal chelators and methods of their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8455688

    HDAC inhibitors

    Lixte Biotechnology, Inc. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8455653

    Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors

    TAKEDA GMBH · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8454958

    Methods for detecting and inhibiting angiogenesis

    The Regents of the University of California · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8455665

    3-phenoxymethylpyrrolidine compounds

    Theravance, Inc. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8455565

    Disulfide monomers comprising ethylenically unsaturated groups suitable for dental compositions

    The Regents of the University of Colorado · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8455621

    Influenza A virus vaccines and inhibitors

    The Board of Regents of the University of Texas System · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8455564

    Dental composition and composite resin

    JGC Catalysts and Chemicals Ltd. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8455507

    Aminopyrimidines useful as kinase inhibitors

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8455530

    Crystalline form of an alkoxyimidazol-1-ylmethyl biphenyl carboxylic acid

    Theravance, Inc. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8455493

    Imidazopyrazine Syk inhibitors

    GILEAD CONNECTICUT, INC. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8455455

    Compositions and methods for silencing genes involved in hemorrhagic fever

    The United States Army Medical Research and Materiel Command · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8455010

    Product and method for producing an immune system supplement and performance enhancer

    Reoxcyn Discoveries Group, Inc. · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8455437

    Method to predict and prevent oxygen-induced inflammatory tissue injury

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8454977

    Non-toxic biofilm inhibitor

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8454972

    Method for inducing a multiclade immune response against HIV utilizing a multigene and multiclade immunogen

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8455435

    Remedies for ischemia

    Ludwig-Maximilians-Universitat Munchen · Granted Tue Jun 04 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 30 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. EP 2599478

    Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff davon

    ACINO AG [DE] · Granted Wed Jun 05 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 31 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8460864

    Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same

    PTC THERAPEUTICS, INC. · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8460643

    Formulation for prophylaxis of oral cavity diseases

    OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU “WELDUP” · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8461155

    Sclerostin and the inhibition of WNT signaling and bone formation

    UNIVERSITY OF CONNECTICUT · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8458818

    Elastomeric gloves and methods of making

    Sentinal Engineering (M) SDN BHD · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8461345

    Processes for producing phenyl-6-(1-(phenyl)ureido)nicotinamides)

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8461295

    Methods for preparing polymeric reagents and compositions of polymeric reagents

    Nektar Therapeutics · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8461203

    Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy

    Jazz Pharmaceuticals, Inc. · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8461298

    Compositions and methods for modification of biomolecules

    The Regents of the University of California · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8461192

    Method of selectively inhibiting PKCiota

    The United States of America—Department of Veterans Affairs · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8461172

    Solid forms and process for preparing

    Corcept Therapeutics Incorporated · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8461187

    Multiple PPI dosage form

    Takeda Pharmaceuticals U.S.A., Inc. · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8461154

    Methods of utilizing arylpiperazine derivatives

    REVIVA PHARMACEUTICALS, INC. · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8461153

    Benzodiazepinone compounds useful in the treatment of skin conditions

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8461156

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8460675

    Viral chemokine-antigen fusion proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8460660

    Anti-mesothelin antibodies

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8460693

    Intraluminal device with a coating containing synthetic fish oil and a therapeutic agent

    ATRIUM MEDICAL CORPORATION · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8461339

    Pharmaceutical compounds

    SENTINEL ONCOLOGY LIMITED · Granted Tue Jun 11 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 06 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.