Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8603543

    Mesocellular oxide foams as hemostatic compositions and methods of use

    The Regents of the University of California · Granted Tue Dec 10 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8604159

    Method for preparing functionalized polymers from polymer alcohols

    Nektar Therapeutics · Granted Tue Dec 10 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8604184

    Chemically programmable immunity

    United States of America as represented by the Secretary of the Air Force · Granted Tue Dec 10 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 05 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8609716

    Chondropsin-class antitumor V-ATPase inhibitor compounds, compositions and methods of use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8609706

    Compounds and methods for inhibiting the interaction of BCL proteins with binding partners

    Infinity Discovery, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8609856

    Crystalline forms of Febuxostat

    Teva Pharmaceuticals USA, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8609838

    Pyrimidine substituted purine derivatives

    VERASTEM, INC. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8609843

    Photoactive metal nitrosyls for blood pressure regulation and cancer therapy

    The Regents of the University of California · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8609848

    Pyrazolone-derivatives and their use as PDE-4 inhibitors

    TAKEDA GMBH · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8609417

    Methods and compositions for stem cell cultures

    The Regents of the University of California · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 8609871

    Process for production of optically active amine derivatives

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 8609728

    Treatment for pulmonary hypertension

    United Therapeutics Corporation · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8609661

    Pyrimido-pyrrolo-quinoxalinedione inhibitors of cystic fibrosis transmembrane conductance regulator protein and uses therefor

    The Regents of the University of California · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8609650

    Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as Axl inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8609607

    Modified defensins and their use

    The United States of America as Represented by the Secretary of the Department of Health and Human Services · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8609367

    Genes and proteins for the biosynthesis of the lantibiotic 107891

    Sentinella Pharmaceuticals, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8609334

    Biomarkers for painful intervertebral discs and methods of use thereof

    The Regents of the University of California · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8609408

    Method for the reconstruction of a tissue-engineered human corneal endothelium

    OCEAN UNIVERSITY OF CHINA · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8609395

    Agonist and antagonist peptides of carcinoembryonic antigen (CEA)

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8609404

    Vaccines containing canine parvovirus genetic variants

    The Board of Regents for Oklahoma State University · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8609412

    Mapc generation of lung tissue

    Regents of the University of Minnesota · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8609608

    Antimicrobial peptides

    The Regents of the University of California · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8609648

    Hepatitis C virus inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8609651

    Pharmaceutical compositions of benzodiazepines and method of use thereof

    Jazz Pharmaceuticals, Inc. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8609703

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8609682

    Analgesic agents

    Regents of the University of Minnesota · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8609235

    Porous ceramic material and method of producing the same

    KURARAY CO., LTD. · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8609162

    Integrated neuromodulation system for mood enhancement of a living human subject

    InVivo Beverages LLC · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8609102

    Antibodies or fragments thereof directed against a Staphylococcus aureus epitope of ISAA or ISAB

    Julius-Maximilians-Universitaet · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8609088

    Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases

    Regents of the University of Minnesota · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8609067

    Method of measuring propulsion in lymphatic structures

    The Board of Regents of the University of Texas System · Granted Tue Dec 17 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 12 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 8613905

    Diagnostic agent

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8613900

    Nanostructured transition metal oxides useful for water oxidation catalysis

    The Regents of the University of California · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8613904

    Methods for diagnosis and intervention of hepatic disorders

    The Regents of the University of Colorado · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8614198

    Hepatitis C dsRNA effector molecules, expression constructs, compositions, and methods of use

    Alnylam Pharmaceuticals, Inc. · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8613963

    Nutritional supplement

    Healthy Drink Discoveries Incorporated · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8613927

    High affinity human antibodies to human nerve growth factor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8614304

    Immunogenic peptides and methods of use for treating and preventing cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Serives · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8614327

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8614325

    Modulators of cystic fibrosis transmembrane conductance regulator

    Vertex Pharmaceuticals Incorporated · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8614183

    Use of FGFR1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in FGFR2

    Five Prime Therapeutics, Inc. · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8614189

    Carbon nanotube composite scaffolds for bone tissue engineering

    UNIVERSITY OF CONNECTICUT · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8614082

    Attenuation of encephalitogenic alphavirus and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8614301

    Methods of treating cancer using anti CD24 antibodies

    The Medical Research, Infrastructure and Health Services Fund of the Tel-Aviv Medical Center · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8614252

    Crystalline solid rasagiline base

    TEVA PHARMACEUTICAL INDUSTRIES, LTD. · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8614208

    Fused heterocyclic ring derivative and use thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8613932

    GP100-specific T cell receptors and related materials and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8613933

    Brachyury polypeptides and methods for use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Dec 24 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 19 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.