Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2033

Annual patent cliff calendar for 2033 — US pharmaceutical patents by expiration date.

Patents
1,330

Quick answer

1,330 indexed pharmaceutical patents have expiration dates in 2033. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 8426379

    POT1 alternative splicing variants

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 8426365

    Method of treating or preventing tissue deterioration, injury or damage due to congestive heart failure

    REGENERX BIOPHARMACEUTICALS, INC. · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 8425933

    Abuse-resistant oral dosage forms and method of use thereof

    Elite Laboratories, Inc. · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 8425930

    Prebiotic oligosaccharides

    The Regents of the University of California · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 8426188

    Attenuated recombinant alphaviruses incapable of replicating in mosquitoes and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 8426179

    Synthetic peptide and peptide conjugates and related tissue coupling methods via transglutaminase enzyme

    Northwestern University · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 8425653

    Plasmon mediated photoinduced synthesis of silver triangular bipyramids

    Northwestern University · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 8425492

    In vivo device, system and usage thereof

    Julius-Maximilians-Universitat Wurzburg · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 8425459

    Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent

    Lutonix, Inc. · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 8425447

    Selective cytopheresis devices and related methods thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Apr 23 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 18 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. CA 2851057

    UTILISATION COMBINEE D'UN GLYCOSAMINOGLYCANE SULFATE ET D'UNE HYALURONIDASE POUR AMELIORER LA BIODISPONIBILITE DU FACTEUR VIII

    CSL BEHRING GMBH [DE] · Granted Thu Apr 25 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 20 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. CA 2852397

    UTILISATION DE GLYCOSAMINOGLYCANES SULFATES POUR AMELIORER LA BIODISPONIBILITE DU FACTEUR VIII

    CSL BEHRING GMBH [DE] · Granted Thu Apr 25 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 20 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 8431532

    FZD8 extracellular domains and FZD8 extracellular domain fusion molecules and treatments using same

    Five Prime Therapeutics, Inc. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 8431570

    Methods of utilizing arylpiperazine derivatives

    REVIVA PHARMACEUTICALS, INC. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 8430832

    Selective cytopheresis devices and related methods thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 8431176

    Liquid chromatographic fraction of enzymatically polymerized flavonoid as an antioxidant

    The United States of America as represented by the Secretary of the Army · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 8431124

    Methods for treating a disease characterized by an excess of hyaluronan by administering a soluble hyaluronidase glycoprotein (sHASEGP)

    HALOZYME, INC. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 8431626

    Disulfide monomers comprising ethylenically unsaturated norbornyl groups suitable for dental compositions

    The Regents of the University of Colorado · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 8431594

    Bridged bicyclic heteroaryl substituted triazoles useful as AXL inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 8431690

    T cell receptors and related materials and methods of use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 8431605

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 8431615

    Dose forms

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 8431556

    C-21-keto lupane derivatives preparation and use thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 8431566

    Cyclopamine lactam analogs and methods of use thereof

    Infinity Discovery, Inc. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 8431561

    Methods and compositions for treatment of excess nitric oxide or cyanide toxicity

    The Regents of the University of California · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 8431558

    Compositions and methods for modification of biomolecules

    The Regents of the University of California · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 8431543

    Chitosan based polymer conjugate and a method for producing the same

    ENGENE, INC. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 8431380

    Soluble hyaluronidase glycoprotein (sHASEGP), process for preparing the same, uses and pharmaceutical compositions comprising thereof

    HALOZYME, INC. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 8431154

    Oral dosage form containing a PDE 4 inhibitor as an active ingredient and polyvinylpyrrolidone as excipient

    TAKEDA GMBH · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 8431116

    Norovirus vaccine formulations

    Takeda Vaccines (Montana), Inc. · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 8431134

    Use of a pneumococcal P4 peptide for enhancing opsonophagocytosis in response to a pathogen

    The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention · Granted Tue Apr 30 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 25 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. AU 2012205809

    Phenethylsulfone isoindoline derivatives as inhibitors of PDE 4 and/or cytokines

    CELGENE CORP [CH] · Granted Thu May 02 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 27 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 8436078

    Dental composition and composite resin

    JGC Catalysts and Chemicals Ltd. · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 8435993

    Methods of inhibiting metastasis from cancer

    Alliance Discovery, Inc. · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 8435504

    Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid

    Nektar Therapeutics · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 8435507

    Prostate-specific antigen-derived MHC class II restricted peptides and their use in vaccines to treat or prevent prostate cancer

    The United States of America as Represented by the Dept. of Veterans Affairs · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 8436224

    Methods for testing for caloric restriction (CR) mimetics

    BioMarker Pharmaceuticals, Inc. · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 8436200

    Process for making (R)-3-(2,3-dihydroxypropyl)-6-fluoro-5-(2-flouro-4- iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione and intermediates thereof

    Takeda Pharmaceutical Company Limited · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 8436014

    Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide

    Vertex Pharmaceuticals Incorporated · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 8436043

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 8435995

    Pyridazinone compounds

    Takeda Pharmaceutical Company Limited · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 8436154

    Crystallizing method of erythromycin

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 8435960

    Devices for improved wound management

    Lakewood Amedex, Inc. · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 8435979

    Use of imipramine blue and analogs thereof in treating cancers

    The United States of America as Represented by the Dept. of Veterans Affairs · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 8435533

    Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of Chlamydia

    The Board of Regents of the University of Texas System · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 8435941

    Mini-hepcidin peptides and methods of using thereof

    The Regents of the University of California · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 8435575

    Use of gingerols for cancer patients suffering from nausea and emesis induced by chemotherapy

    Aphios Corporation · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 8435570

    Nitrite formulations and their use as nitric oxide prodrugs

    The Board of Regents of the University of Texas System · Granted Tue May 07 2013 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 02 2033 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2033?

1,330 published patents in our USPTO index have expiration dates falling in calendar year 2033.