Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. PLERIXAFOR, Casgevy 4 - 13 x 10^6 cells/mL dispersion for infusion, BUSULFAN

    Vertex Pharmaceuticals (Australia) Pty.

    Severe sickle cell disease (SCD)

    phase 2 small molecule active

    1 trial
  2. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Primary Sclerosing Cholangitis

    phase 2 small molecule completed

    1 trial
  3. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule completed

    4 trials
  4. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Acute Respiratory Distress Syndrome

    phase 2 small molecule terminated

    1 trial
  5. PM14, IRINOTECAN

    Lacuna Pharma Pty Ltd

    Patients with Selected Advanced Solid Tumors

    phase 2 small molecule active

    1 trial
  6. PM359

    Prime Medicine

    Chronic Granulomatous Disease

    phase 2 mab active

    1 trial
  7. PM8002

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  8. PN-943

    Protagonist Therapeutics, Inc

    Ulcerative Colitis Chronic Moderate

    phase 2 small molecule completed

    1 trial
  9. POMALIDOMIDE , ELRANATAMAB, AZD0305, ELRANATAMAB

    AstraZeneca AB

    Multiple Myeloma

    phase 2 small molecule active

    1 trial
  10. POMALIDOMIDE, POMALIDOMIDE, DEXAMETHASONE, CARFILZOMIB, BORTEZOMIB, POMALIDOMIDE, CARFILZOMIB, POMALIDOMIDE, CARFILZOMIB, DEXAMETHASONE

    GlaxoSmithKline

    Relapsed or Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial
  11. POMALIDOMIDE, POMALIDOMIDE, POMALIDOMIDE, POMALIDOMIDE, DARZALEX 1800 mg solution for injection, DEXAMETHASONE, DEXAMETHASONE

    Wuhan Createrna Science and Technology Co., Ltd

    Relapsed/refractory multiple myeloma

    phase 2 small molecule active

    1 trial
  12. PONATINIB, CYCLOPHOSPHAMIDE, VINCRISTINE, BESPONSA 1 mg powder for concentrate for solution for infusion, METHOTREXATE, PURINETHOL 50 mg compresse, PREDNISONE

    Fondazione Telethon ETS

    Acute B-cell Lymphoblastic Leukemia with minimal residual positive disease prior to haematopoietic stem cell transplantation in adult patients

    phase 2 small molecule active

    1 trial
  13. POST Triheptanoin

    Ultragenyx UK Limited

    Frontal Lobe Hypometabolism

    phase 2 small molecule completed

    1 trial
  14. POTASSIUM IODIDE

    Cellectar Biosciences

    Waldenstrom Macroglobulinemia

    phase 2 small molecule active

    1 trial
  15. POTELIGEO 4 mg/mL concentrate for solution for infusion

    KYOWA KIRIN AUSTRALIA PTY LTD

    Mycosis fungoides/Sezary syndrome recurrent

    phase 2 small molecule active

    1 trial
  16. PPRS

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Use

    phase 2 other completed

    1 trial
  17. PPY988A

    Novartis Pharmaceuticals

    Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) in participants already treated with GT005 in the previous studies GT005-01 (FOCUS), GT005-02 (EXPLORE) and GT005-03 (HORIZON).

    phase 2 small molecule active

    1 trial
  18. PRAM9

    Xeris Biopharma Holdings

    Diabetes Mellitus, Type 1

    phase 2 small molecule completed

    1 trial
  19. PRAVASTATIN

    The George Institute

    Patients with severe and radio-induced breast fibrosis after breast cancer

    phase 2 small molecule active

    1 trial
  20. PRAX-222 - Initial Dose

    Chongqing Precision Biotech Co., Ltd

    SCN2A-DEE

    phase 2 small molecule active

    1 trial
  21. PRAX-628

    Chongqing Precision Biotech Co., Ltd

    Focal onset seizures or primary generalized tonic-clonic seizures

    phase 2 small molecule active

    1 trial
  22. PREDNISOLONE , MabThera 100 mg concentrate for solution for infusion, PREDNISONE , MabThera 500 mg concentrate for solution for infusion

    Pari Pharma GmbH

    Minimal Change Nephrotic Syndrom

    phase 2 small molecule active

    1 trial
  23. PREDNISONE , ABIRATERONE , MDV3100

    Astellas Pharma GmbH

    Prostate Cancer

    phase 2 small molecule active

    1 trial
  24. PREDNISONE, PREDNISOLONE, BOSENTAN

    Pari Pharma GmbH

    Newly diagnosed or relapsing Giant-cell arteritis

    phase 2 small molecule active

    1 trial
  25. PREGABALIN, VX-993 tablet, VX-993 Placebo, VX-993 tablet, PREGABALIN, Pregabalin placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Pain Associated With Diabetic Peripheral Neuropathy

    phase 2 small molecule active

    1 trial
  26. PRENUMBRA

    Clinuvel Europe Limited

    Parkinson's Disease

    phase 2 small molecule active

    1 trial
  27. PRENUMBRA

    Clinuvel Europe Limited

    Arterial Ischaemic Stroke (AIS)

    phase 2 small molecule active

    1 trial
  28. PRENUMBRA

    Clinuvel Europe Limited

    Healthy volunteers

    phase 2 small molecule active

    1 trial
  29. PRO044 SC

    BioMarin Pharmaceutical Australia Pty Ltd

    Duchenne Muscular Dystrophy

    phase 2 small molecule completed

    1 trial
  30. PRO044 SC 6 mg/kg

    BioMarin Pharmaceutical Australia Pty Ltd

    Duchenne Muscular Dystrophy

    phase 2 small molecule terminated

    1 trial
  31. PRO045, 0.15 mg/kg/week

    BioMarin Pharmaceutical Australia Pty Ltd

    Duchenne Muscular Dystrophy

    phase 2 small molecule terminated

    1 trial
  32. PROLEUKIN 18 millions U.I., poudre pour solution injectable, CHLORURE DE SODIUM 0,9 % B. BRAUN, solution injectable en ampoule

    Pari Pharma GmbH

    Alzheimer Disease

    phase 2 small molecule active

    1 trial
  33. PROLEUKIN® 18 x 106 IU Powder for solution for injection or infusion, Lifileucel, Cyclophosphamide Injection 1 g, FLUDARABINE

    Iovance Biotherapeutics B.V.

    Previously treated advanced melanoma

    phase 2 small molecule active

    1 trial
  34. PROMETHAZINE , DIPHENHYDRAMINE , CETIRIZINE , DEXCHLORPHENIRAMINE , PARACETAMOL , SAR443579

    Sanofi-aventis Healthcare Pty Ltd

    Acute lymphocytic leukaemia- Acute myeloid leukaemia refractory - Myelodysplastic syndrome - Blastic plasmacytoid dendritic cell neoplasia

    phase 2 small molecule active

    1 trial
  35. PRT3789

    Prelude Therapeutics Inc

    Advanced Solid Tumor

    phase 2 small molecule completed

    2 trials
  36. PRX-100

    LENZ Therapeutics

    Presbyopia

    phase 2 small molecule completed

    1 trial
  37. PRX-112

    Protalix BioTherapeutics

    Gaucher Disease

    phase 2 small molecule completed

    2 trials
  38. PRX-115

    Protalix BioTherapeutics

    Gout

    phase 2 mab active

    2 trials
  39. PS433540

    LIGAND PHARMACEUTICALS INC

    Hypertension

    phase 2 small molecule completed

    1 trial
  40. PSMA PET/MR - Gallium-68 labeled PSMA-HBED-CC

    Telix Innovations

    Prostate Cancer

    phase 2 small molecule active

    1 trial
  41. PT150

    United Therapeutics Europe Ltd

    PTSD - Post Traumatic Stress Disorder

    phase 2 small molecule active

    1 trial
  42. PTC124

    PTC THERAPEUTICS, INC.

    Cystic Fibrosis

    phase 2 small molecule completed

    2 trials
  43. PTC124

    PTC THERAPEUTICS, INC.

    Duchenne Muscular Dystrophy

    phase 2 small molecule completed

    1 trial
  44. PTC299

    PTC THERAPEUTICS, INC.

    Neurofibromatosis 2

    phase 2 small molecule terminated

    1 trial
  45. PTC518

    PTC THERAPEUTICS, INC.

    Huntington Disease

    phase 2 small molecule completed

    1 trial
  46. PTC857

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule terminated

    1 trial
  47. PTC857, Placebo to match PTC857 60 mg/mL oral solution, Utreloxastat 62.5

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule active

    1 trial
  48. PTC923

    PTC THERAPEUTICS, INC.

    BH4 Deficiency

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs