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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Panobinostat

    Zealand Pharma A/S

    Rhabdoid Tumor

    phase 2 small molecule terminated

    1 trial

  2. Panobinostat Capsules

    pharmaand GmbH

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  3. Pantoprazole 40mg

    Zealand Pharma A/S

    Oncology

    phase 2 small molecule completed

    1 trial

  4. Panzem (2-methoxyestradiol) NCD, Avastin (Bevacizumab)

    CASI Pharmaceuticals

    Carcinoid Tumor

    phase 2 small molecule completed

    1 trial

  5. Panzem NCD

    CASI Pharmaceuticals

    Recurrent Glioblastoma Multiforme

    phase 2 small molecule completed

    1 trial

  6. Panzem Nanocrystal Colloidal Dispersion

    CASI Pharmaceuticals

    Recurrent Glioblastoma Multiforme

    phase 2 small molecule completed

    1 trial

  7. Panzem Nanocrystal Colloidal Dispersion (NCD)

    CASI Pharmaceuticals

    Ovarian Cancer

    phase 2 small molecule completed

    1 trial

  8. Panzem® NCD

    CASI Pharmaceuticals

    Metastatic Renal Cell Carcinoma

    phase 2 small molecule completed

    1 trial

  9. Panzem® NCD

    CASI Pharmaceuticals

    Prostate Cancer

    phase 2 small molecule completed

    1 trial

  10. Para-Tabs 500 mg tabletti, ODM-111 Placebo, ODM-111, ODM-111

    Orion Laboratories Pty.

    CHRONIC PAIN DUE TO DIABETIC PERIPHERAL NEUROPATHY

    phase 2 small molecule active

    1 trial

  11. Paracetamol/Codeine phosphate hemihydrate Accord 500 mg/30 mg tablets, PARACETAMOL, DFV890, Placebo to DFV890 10mg, Placebo to DFV890 25mg, DFV890

    Novartis Pharmaceuticals

    Knee Osteoarthritis

    phase 2 small molecule active

    1 trial

  12. Parenteral Remodulin (treprostinil) injection

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 2 small molecule terminated

    1 trial

  13. Parenting in 2 Worlds (P2W)

    BRIGHT MINDS BIOSCIENCES INC.

    Parenting

    phase 2 other active

    1 trial

  14. Pariglasgene brecaparvovec

    Lacuna Pharma Pty Ltd

    Glycogen storage disease type Ia

    phase 2 small molecule active

    1 trial

  15. Parsaclisib

    Incyte

    Lymphoma

    phase 2 small molecule completed

    1 trial

  16. Part 1: VP-315 3 Day Dosing/Week

    Verrica Pharmaceuticals

    Basal Cell Carcinoma

    phase 2 small molecule completed

    1 trial

  17. Part A: 20 and 40 mg PRAX-944

    Chongqing Precision Biotech Co., Ltd

    Essential Tremor

    phase 2 small molecule completed

    1 trial

  18. Part A: RM-718 or placebo (matched to specific RM-718 dose cohort)

    Rhythm Pharmaceuticals Netherlands B.V.

    Hypothalamic Obesity

    phase 2 small molecule active

    1 trial

  19. Part1:Recombinant two-component COVID-19 vaccine (CHO cell)

    Jian Li

    COVID-19

    phase 2 mab completed

    1 trial

  20. Patisiran

    Alnylam Netherlands B.V.

    TTR-mediated Amyloidosis

    phase 2 small molecule completed

    1 trial

  21. Patritumab deruxtecan

    Daiichi Sankyo

    Metastatic or Locally Advanced EGFR mutated Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  22. Patritumab deruxtecan

    Daiichi Sankyo

    Locally Advanced or Metastatic Solid Tumors

    phase 2 small molecule active

    1 trial

  23. Patupilone

    Novartis Pharmaceuticals

    Hepatocellular Carcinoma

    phase 2 small molecule completed

    1 trial

  24. Paxalisib

    KAZIA THERAPEUTICS LTD

    Childhood Cancer

    phase 2 small molecule active

    1 trial

  25. Paxalisib

    KAZIA THERAPEUTICS LTD

    Malignant Primary Gliomas

    phase 2 small molecule active

    1 trial

  26. Paxalisib

    KAZIA THERAPEUTICS LTD

    Glioblastoma

    phase 2 small molecule on hold

    1 trial

  27. Paxalisib (GDC-0084)

    KAZIA THERAPEUTICS LTD

    Glioblastoma, Adult

    phase 2 small molecule completed

    1 trial

  28. Pear

    NORTHWEST BIOTHERAPEUTICS INC

    Metabolic Syndrome

    phase 2 other completed

    1 trial

  29. Pectin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Slow Transit Constipation

    phase 2 small molecule active

    1 trial

  30. Pedmark® STS

    FENNEC PHARMACEUTICALS INC.

    Solid Tumor Malignancies

    phase 2 small molecule active

    1 trial

  31. Pegaspargase Combined With Gemcitabine, Etoposide, Liposomal Mitoxantrone Hydrochloride and Dexamethasone (P-GEMD) regimen

    The First People's Hospital of Lianyungang

    NK-T-Cell Lymphoma, Extranodal

    phase 2 small molecule active

    1 trial

  32. Pegasys 180 micrograms solution for injection in pre-filled syringe, VIR-3434, Viread 245 mg film-coated tablets, VIR-2218

    Vir Biotechnology

    Chronic Hepatitis B Virus (HBV) Infection

    phase 2 small molecule active

    1 trial

  33. Pegcetacoplan

    Apellis Europe B.V.

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule active

    2 trials

  34. Pegcetacoplan

    Apellis Europe B.V.

    Transplant-Associated Thrombotic Microangiopathy

    phase 2 small molecule completed

    1 trial

  35. Pegcetacoplan

    Apellis Europe B.V.

    Geographic Atrophy

    phase 2 small molecule completed

    1 trial

  36. Pegcetacoplan

    Apellis Europe B.V.

    Neovascular Age-related Macular Degeneration

    phase 2 small molecule terminated

    2 trials

  37. Pegcetacoplan (APL-2)

    Apellis Europe B.V.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule terminated

    1 trial

  38. Pegvorhyaluronidase alfa

    HALOZYME THERAPEUTICS, INC.

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule terminated

    1 trial

  39. Pegylated Irinotecan

    Nektar Therapeutics UK Limited

    Recurrent Small Cell Lung Carcinoma

    phase 2 small molecule completed

    1 trial

  40. Pegylated Irinotecan

    Nektar Therapeutics UK Limited

    Stage IV Non-small Cell Lung Cancer (NSCLC)

    phase 2 small molecule completed

    1 trial

  41. Peiyuan Guben Tongluo Ointment (Ejiao concentrated)

    Universal Integrated

    Sarcopenia in Elderly

    phase 2 small molecule active

    1 trial

  42. Pelareorep

    ONCOLYTICS BIOTECH INC

    Anal Cancer Metastatic

    phase 2 small molecule active

    1 trial

  43. Pelareorep

    ONCOLYTICS BIOTECH INC

    Anatomic Stage IV Breast Cancer AJCC v8

    phase 2 mab active

    1 trial

  44. Pemazyre 4.5 mg tablets

    The George Institute

    locally advanced intrahepatic cholangiocarcinoma (iCCA) with FGFR2 fusions/rearrangements

    phase 2 small molecule active

    1 trial

  45. Pemazyre 4.5 mg tablets

    Ningbo Cancer Hospital

    Recurrent or metastatic solid cancer harboring a FGFR1,2 ,3 fusion/rearrangement or activating mutation, outside of the approved indications for any selective FGFR inhibitor in France

    phase 2 small molecule active

    1 trial

  46. Pemazyre 4.5 mg tablets, INCAGN02385, INCAGN02390, Retifanlimab (INCMGA00012)

    Incyte

    Endometrial cancer, Endometrial cancer

    phase 2 small molecule active

    1 trial

  47. Pembrolizumab

    United Therapeutics Europe Ltd

    Pancreatic Cancer

    phase 2 small molecule active

    1 trial

  48. Pembrolizumab

    Genmab A/S

    Advanced Endometrial Cancer

    phase 2 mab terminated

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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