Tuesday, July 21, 2026
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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 135
Sponsors 800
Drugs 4,222

Quick answer

NovaPharmaNews tracks 135 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 2 of 3

  1. IIT2024067

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    AML

    phase 2 small molecule active

    1 trial

  2. INO-5401

    INOVIO PHARMACEUTICALS, INC.

    Glioblastoma

    phase 2 mab active

    1 trial

  3. IONIS GHR-LRx

    IONIS PHARMACEUTICALS INC

    Acromegaly

    phase 2 small molecule completed

    2 trials

  4. IOV-COM-202

    Iovance Biotherapeutics B.V.

    Neoplasm

    phase 2 small molecule active

    1 trial

  5. IPV26

    Sanofi Pasteur

    Poliomyelitis

    phase 2 mab completed

    1 trial

  6. IRST191.05

    Istituto Gentili S.r.l.

    Glioblastoma

    phase 2 small molecule active

    1 trial

  7. ISIS-FGFR4RX

    IONIS PHARMACEUTICALS INC

    Obesity

    phase 2 small molecule completed

    1 trial

  8. Ibrutinib

    Karyopharm Therapeutics Inc

    Lymphoma

    phase 2 small molecule active

    1 trial

  9. Iguratimod

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    ITP

    phase 2 small molecule active

    1 trial

  10. Iloperidone crystalline formulation

    Vanda Pharmaceuticals Netherlands B.V.

    Schizophrenia

    phase 2 small molecule completed

    1 trial

  11. Immunization with P. vivax irradiated sporozoites

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria

    phase 2 mab completed

    1 trial

  12. Inactivated Poliomyelitis vaccine (IMOVAX)

    Sanofi Pasteur

    Poliomyelitis

    phase 2 mab completed

    1 trial

  13. Infigratinib

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule active

    1 trial

  14. Infigratinib 0.016 mg/kg

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule completed

    1 trial

  15. Infigratinib is provided as a single dose of minitablets for oral administration

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule active

    1 trial

  16. Inhaled Treprostinil

    United Therapeutics Europe Ltd

    Sarcoidosis

    phase 2 small molecule completed

    1 trial

  17. Iparomlimab and Tuvonralimab Injection (QL1706)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cholangiocarcinoma

    phase 2 small molecule active

    1 trial

  18. Isis 420915/GSK 299872

    IONIS PHARMACEUTICALS INC

    Amyloidosis

    phase 2 small molecule terminated

    1 trial

  19. Ivonescimab

    Summit Therapeutics

    Glioblastoma

    phase 2 small molecule active

    1 trial

  20. JBT-101

    Corbus Pharmaceuticals Holdings

    Dermatomyositis

    phase 2 small molecule terminated

    1 trial

  21. KAI-7535

    Kailera Therapeutics

    Obesity

    phase 2 small molecule active

    2 trials

  22. LUM001

    Mirum Pharmaceuticals International B.V.

    PBC

    phase 2 small molecule completed

    1 trial

  23. Lenvatinib

    Eisai Co.,

    Osteosarcoma

    phase 2 small molecule completed

    1 trial

  24. Linperlisib combination with obinutuzumab

    The First People's Hospital of Lianyungang

    Lymphoma

    phase 2 small molecule active

    1 trial

  25. Lomustine "medac" 40 mg, Fibromun

    Philogen S.p.A.

    Glioblastoma

    phase 2 small molecule active

    1 trial

  26. Luvadaxistat

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia

    phase 2 small molecule completed

    2 trials

  27. ML-007C-MA

    MapLight Therapeutics

    Schizophrenia

    phase 2 small molecule active

    1 trial

  28. Melphalan

    Ultragenyx UK Limited

    Amyloidosis

    phase 2 small molecule completed

    1 trial

  29. Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine (adjuvant-free)

    BRIGHT MINDS BIOSCIENCES INC.

    Meningitis

    phase 2 mab active

    1 trial

  30. Mifamurtide

    Takeda

    Osteosarcoma

    phase 2 small molecule terminated

    1 trial

  31. Mitapivat

    Agios Netherlands B.V.

    Anemia

    phase 2 small molecule active

    1 trial

  32. MultiStem

    United Therapeutics Europe Ltd

    Trauma

    phase 2 mab active

    1 trial

  33. NKTR-102 100 mg/m2

    Nektar Therapeutics UK Limited

    Tumor

    phase 2 small molecule completed

    1 trial

  34. NKTR-102 q14d

    Nektar Therapeutics UK Limited

    Tumor

    phase 2 small molecule completed

    1 trial

  35. NMDAE

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 small molecule active

    2 trials

  36. NMDAE plus AIFA

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenia

    phase 2 small molecule active

    1 trial

  37. Nabiximols

    Jazz Pharmaceuticals Ireland Limited

    Glioblastoma

    phase 2 small molecule active

    1 trial

  38. Naltrexone hydrochloride

    BRIGHT MINDS BIOSCIENCES INC.

    Obesity

    phase 2 small molecule active

    1 trial

  39. Nivolumab

    Nektar Therapeutics UK Limited

    Ependymoma

    phase 2 mab terminated

    1 trial

  40. Open Label Selinexor

    Karyopharm Therapeutics Inc

    Thymoma

    phase 2 small molecule terminated

    1 trial

  41. Oral CEP-701

    Teva Pharma GmbH

    Myeloma

    phase 2 small molecule terminated

    1 trial

  42. Paltusotine tablets, Paltusotine tablets

    Lacuna Pharma Pty Ltd

    Acromegaly

    phase 2 small molecule active

    1 trial

  43. Parsaclisib

    Incyte

    Lymphoma

    phase 2 small molecule completed

    1 trial

  44. Paxalisib

    KAZIA THERAPEUTICS LTD

    Glioblastoma

    phase 2 small molecule on hold

    1 trial

  45. Pimavanserin 34 milligrams (MG) [Nuplazid]

    Acadia Pharmaceuticals B.V.

    Schizophrenia

    phase 2 small molecule terminated

    1 trial

  46. Placebo

    MapLight Therapeutics

    Schizophrenia

    phase 2 small molecule active

    1 trial

  47. Pramlintide+Metreleptin

    Takeda

    Obesity

    phase 2 small molecule terminated

    1 trial

  48. Preoperative lanreotide treatment

    The First People's Hospital of Lianyungang

    Acromegaly

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

135 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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