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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. silevertinib in combination with temozolomide

    Blackmores Limited

    Glioblastoma (GBM)

    phase 2 small molecule active

    1 trial

  2. sintilimab

    The First People's Hospital of Lianyungang

    Colorectal Neoplasms

    phase 2 small molecule active

    1 trial

  3. sintilimab

    The First People's Hospital of Lianyungang

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial

  4. sintilimab+IBI310+chemotherapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC Stage II

    phase 2 small molecule active

    1 trial

  5. sintiliman plus LDRT

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Gastric Cancer

    phase 2 small molecule active

    1 trial

  6. sirolimus

    Cardiff Oncology

    Tuberous Sclerosis

    phase 2 small molecule active

    1 trial

  7. sodium chloride 9 mg/ml (0.9%) solution for injection, LIBTAYO 350 mg concentrate for solution for infusion.

    The George Institute

    Merkel Cell Carcinoma

    phase 2 small molecule active

    1 trial

  8. sodium oxybate

    Jazz Pharmaceuticals Ireland Limited

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  9. sotatercept, PL1 - Powder for injection

    Lacuna Pharma Pty Ltd

    Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) due to Heart Failure with Preserved Ejection Fraction (HFpEF)

    phase 2 small molecule active

    1 trial

  10. sotatercept, SOTATERCEPT, sotatercept, SOTATERCEPT

    Merck Sharp and Dohme

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule active

    1 trial

  11. split-virion pandemic influenza vaccine (H5N1 strain NIBRG-14)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Influenza

    phase 2 mab completed

    2 trials

  12. ssCART-19

    The First People's Hospital of Lianyungang

    Relapsed or Refractory Acute Lymphoblastic Leukemia

    phase 2 mab active

    1 trial

  13. ssCART-19 cells combined with CD19+ feeding T cells (FTCs) infusion

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia, Adult B-Cell

    phase 2 mab active

    1 trial

  14. standard of care (SOC) Nucleoside reverse transcriptase inhibitor (NrtI)

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 2 small molecule terminated

    1 trial

  15. standard triple region

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Helicobacter Pylori Infection

    phase 2 small molecule completed

    1 trial

  16. sterile saline solution (0.9% w/v solution of NaCl in water).

    GlaxoSmithKline

    Urinary Tract Infections

    phase 2 small molecule active

    1 trial

  17. sublingual nitroglycerine

    United Therapeutics Europe Ltd

    COLIC

    phase 2 small molecule active

    1 trial

  18. sublingual tizanidine 12 mg

    Teva Pharma GmbH

    Spasticity

    phase 2 small molecule terminated

    1 trial

  19. sunitinib added to FOLFIRI

    BRIGHT MINDS BIOSCIENCES INC.

    Metastatic Colorectal Cancer

    phase 2 small molecule completed

    1 trial

  20. surufatinib + fulvestrant + chidamide

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial

  21. talampanel

    Teva Pharma GmbH

    Dyskinesias

    phase 2 small molecule completed

    1 trial

  22. tamuzimod, tamuzimod, tamuzimod, VTX002 placebo film-coated tablets matching VTX002, tamuzimod

    Lacuna Pharma Pty Ltd

    Moderately to Severely Active Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  23. tauroursodeoxycholic acid (TUDCA)

    The First People's Hospital of Lianyungang

    Metabolic Dysfunction-Associated Steatotic Liver Disease Infant Development

    phase 2 small molecule active

    1 trial

  24. tbo-filgrastim

    Teva Pharma GmbH

    Neutropenia

    phase 2 small molecule completed

    1 trial

  25. teclistamab, JNJ-64407564, JNJ-64407564, teclistamab, DARZALEX 1800 mg solution for injection

    Janssen-Cilag International N.V.

    Multiple Myeloma

    phase 2 small molecule active

    1 trial

  26. teclistamab, Privigen 100 mg/ml solution for infusion, Privigen 100 mg/ml solution for infusion, teclistamab, Privigen 100 mg/ml solution for infusion

    Janssen-Cilag International N.V.

    Relapsed/Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial

  27. telaprevir

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Hepatitis C Virus Infection

    phase 2 small molecule terminated

    1 trial

  28. telaprevir or matching placebo

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 2 small molecule completed

    1 trial

  29. telephone based skills training intervention

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 other completed

    1 trial

  30. temozolomide

    Universal Integrated

    Cancer

    phase 2 small molecule completed

    1 trial

  31. temozolomide

    Children's Hospital of Fudan University

    Brain and Central Nervous System Tumors

    phase 2 small molecule completed

    1 trial

  32. thalidomide

    Ultragenyx UK Limited

    HIV Infections

    phase 2 small molecule completed

    1 trial

  33. the standard "3+7" regimen

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Newly Diagnosed Acute Myeloid Leukemia (AML)

    phase 2 small molecule active

    1 trial

  34. therapeutic autologous dendritic cells

    LISATA THERAPEUTICS, INC.

    Melanoma (Skin)

    phase 2 mab completed

    1 trial

  35. tin mesoporphyrin

    Ultragenyx UK Limited

    Hyperbilirubinemia

    phase 2 small molecule completed

    1 trial

  36. tin mesoporphyrin

    Ultragenyx UK Limited

    Glucosephosphate Dehydrogenase Deficiency

    phase 2 small molecule completed

    1 trial

  37. tiotropium-bromide

    Boehringer Ingelheim

    Asthma

    phase 2 small molecule completed

    1 trial

  38. tislelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stage III

    phase 2 small molecule active

    1 trial

  39. tislelizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Gastric

    phase 2 small molecule active

    1 trial

  40. tisotumab vedotin

    Genmab A/S

    Solid Tumor

    phase 2 small molecule completed

    1 trial

  41. topiramate

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    1 trial

  42. toripalimab

    The First People's Hospital of Lianyungang

    Malignant Melanoma

    phase 2 small molecule active

    1 trial

  43. tovinontrine-matching placebo, immediate-release tablet, Tovinontrine

    Lacuna Pharma Pty Ltd

    chronic heart failure

    phase 2 small molecule active

    1 trial

  44. tramadol

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Abuse

    phase 2 small molecule completed

    1 trial

  45. transdermal nicotine

    BRIGHT MINDS BIOSCIENCES INC.

    Cigarette Smoking

    phase 2 small molecule completed

    1 trial

  46. treprostinil dienthanolmine sustained release

    United Therapeutics Europe Ltd

    Critical Limb Ischemia

    phase 2 small molecule completed

    1 trial

  47. treprostinil diethanolamine

    United Therapeutics Europe Ltd

    Systemic Sclerosis

    phase 2 small molecule completed

    2 trials

  48. trifluridine/tipiracil combined with fufuquitinib

    The First People's Hospital of Lianyungang

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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