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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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Page 93 of 151

  1. PALONOSETRON, Jakavi 10 mg tablets, ONDANSETRON, NETUPITANT, APREPITANT, PACRITINIB, Jakavi 5 mg tablets, SELINEXOR

    Karyopharm Therapeutics Inc

    moderate thrombocytopenia, JAK inhibitor-naïve myelofibrosis

    phase 2 small molecule active

    1 trial

  2. PARACETAMOL , FEXOFENADINE , CETIRIZINE , DEXAMETHASONE , mRNA-3745, DIPHENHYDRAMINE , CARBOHYDRATES , IBUPROFEN , HYDROXYZINE , FAMOTIDINE , Isotonische Kochsalzlösung Fresenius, Infusionslösung, ONDANSETRON

    Moderna Biotech Spain

    Glycogen storage disease type 1a (GSD1a)

    phase 2 small molecule active

    1 trial

  3. PARACETAMOL, DIPHENHYDRAMINE, INFLIXIMAB, TOCILIZUMAB, AZD7789, EPINEPHRINE

    AstraZeneca AB

    Relapsed/Refractory Classical Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  4. PARACETAMOL, Placebo to QUC398 150 mg/1 mL Solution for injection, QUC398, Paracetamol/Codeine phosphate hemihydrate Accord 500 mg/30 mg tablets

    Novartis Pharmaceuticals

    Knee osteoarthritis

    phase 2 small molecule active

    1 trial

  5. PARP inhibitor 2X-121

    Allarity Therapeutics

    Metastatic Breast Cancer

    phase 2 small molecule completed

    1 trial

  6. PAXALISIB

    KAZIA THERAPEUTICS LTD

    Primary Central Nervous System Lymphoma

    phase 2 small molecule active

    1 trial

  7. PBCAR20A

    Chongqing Precision Biotech Co., Ltd

    Non-Hodgkin's Lymphoma, Relapsed

    phase 2 gene therapy completed

    1 trial

  8. PBGENE-DMD (IV)

    Chongqing Precision Biotech Co., Ltd

    Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD

    phase 2 mab active

    1 trial

  9. PBSC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stem Cell Transplantation, Hematopoietic

    phase 2 mab active

    1 trial

  10. PBSC transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Liver Cirrhosis

    phase 2 other active

    1 trial

  11. PC-SOD

    The First People's Hospital of Lianyungang

    Myocardial Reperfusion Injury

    phase 2 small molecule active

    1 trial

  12. PC14586

    PMV Pharmaceuticals

    Locally Advanced or Metastatic Solid Tumors Harboring a TP53 Y220C Mutation

    phase 2 small molecule active

    1 trial

  13. PCAR-019 (anti-CD19 CAR-T cells)

    The First People's Hospital of Lianyungang

    Acute Lymphocytic Leukemia

    phase 2 mab active

    1 trial

  14. PCI

    Rhythm Pharmaceuticals Netherlands B.V.

    Myocardial Infarction

    phase 2 other completed

    1 trial

  15. PCN-101

    Chongqing Precision Biotech Co., Ltd

    Treatment Resistant Depression

    phase 2 small molecule completed

    1 trial

  16. PCS12852

    Processa Pharmaceuticals

    Gastroparesis

    phase 2 small molecule completed

    1 trial

  17. PCS499

    Processa Pharmaceuticals

    Necrobiosis Lipoidica

    phase 2 small molecule completed

    2 trials

  18. PCS6422 and capecitabine

    Processa Pharmaceuticals

    Breast Cancer

    phase 2 small molecule active

    1 trial

  19. PD -1/PD-L1 monoclonal antibody plus radiotherapy and liver transplantation

    The First People's Hospital of Lianyungang

    Locally Advanced Perihilar Cholangiocarcinoma

    phase 2 other active

    1 trial

  20. PD 0332991

    Pfizer

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  21. PD-1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rectal Cancer Patients

    phase 2 small molecule active

    1 trial

  22. PD-1 Inhibitor plus Chemotherapy

    Sichuan University

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  23. PD-1 antibody Sintilimab

    The First People's Hospital of Lianyungang

    Multiple Primary Lung Cancers

    phase 2 small molecule active

    1 trial

  24. PD-1 inhbitor+SHR0302

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  25. PD-1 inhibitor

    The First People's Hospital of Lianyungang

    Advanced NSCLC

    phase 2 small molecule active

    1 trial

  26. PD-1/CTLA-4 Dual Functional Antibody

    The First People's Hospital of Lianyungang

    Bile Duct Carcinoma

    phase 2 small molecule active

    1 trial

  27. PD-1/PD-L1 inhibitors

    BEONE MEDICINES AUS PTY LTD

    Borderline Resectable Carcinoma

    phase 2 small molecule active

    1 trial

  28. PD-1inhibitor

    Shanghai Chest Hospital

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  29. PD-L1 peptide

    IO Biotech

    Smoldering Multiple Myeloma

    phase 2 mab terminated

    1 trial

  30. PD-L1, PD-L2 peptides with Montanide ISA51

    IO Biotech

    Chronic Lymphocytic Leukemia

    phase 2 other completed

    1 trial

  31. PDC-1421 Capsule

    ABVC BIOPHARMA, INC.

    Attention-Deficit Hyperactivity Disorder (ADHD)

    phase 2 small molecule completed

    1 trial

  32. PDI-192

    Chongqing Precision Biotech Co., Ltd

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial

  33. PDI-320

    Chongqing Precision Biotech Co., Ltd

    Rosacea

    phase 2 small molecule active

    1 trial

  34. PEG-IFNα

    Vir Biotechnology

    Chronic Hepatitis B Virus Infection

    phase 2 mab active

    1 trial

  35. PEG-liposomal prednisolone sodium phosphate

    Lakefront Biotherapeutics NV

    Acute Exacerbation of Remitting Relapsing Multiple Sclerosis

    phase 2 small molecule terminated

    1 trial

  36. PEG-somatropin

    The First People's Hospital of Lianyungang

    Dwarfism

    phase 2 small molecule active

    1 trial

  37. PEG-somatropin

    Changchun GeneScience Pharmaceutical Co.,

    Dwarfism

    phase 2 small molecule active

    1 trial

  38. PEG-somatropin

    The First People's Hospital of Lianyungang

    Short Stature Children Born Small for Gestational Age (SGA)

    phase 2 mab active

    1 trial

  39. PEGENZILEUKIN, Isatuximab, Isatuximab

    Sanofi-aventis Healthcare Pty Ltd

    Cancer

    phase 2 small molecule active

    1 trial

  40. PEGFILGRASTIM , Rinatabart Sesutecan

    Genmab A/S

    Locally advanced or metastatic Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  41. PEGINTERFERON ALFA-2A , TIL cells, Zirconium Zr 89 crefmirlimab berdoxam

    Disc Medicine

    Metastatic Melanoma

    phase 2 small molecule active

    1 trial

  42. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Metastatic Pancreatic Adenocarcinoma

    phase 2 small molecule completed

    1 trial

  43. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Metastatic Pancreatic Cancer

    phase 2 small molecule completed

    1 trial

  44. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial

  45. PEMBROLIZUMAB

    Pari Pharma GmbH

    Kaposi's sarcoma

    phase 2 small molecule active

    1 trial

  46. PEMBROLIZUMAB , EIK1001 solution for injection 1.0 mg/mL free base equivalent, Inactive control which is identical in appearance and composition as EIK1001 drug product except for the lack of EIK1001 drug substance

    Eikon Therapeutics

    Stage 4 (IV) Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  47. PEMBROLIZUMAB, ATEZOLIZUMAB, NIVOLUMAB, CEMIPLIMAB

    Fondazione Telethon ETS

    Unresectable or metastatic melanoma, Locally advanced or metastatic urothelial carcinoma, Locally advanced or metastatic non-small cell lung cancer (NSCLC), Untreated recurrent/metastatic head & neck sqamous cell carcinoma (HNSCC)

    phase 2 small molecule active

    1 trial

  48. PEMBROLIZUMAB, DARAXONRASIB (RMC-6236), CARBOPLATIN, DARAXONRASIB (RMC-6236), PEMETREXED, CISPLATIN, RMC-9805

    Revolution Medicines

    Lung Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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