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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. PEMBROLIZUMAB, OLAPARIB, OLAPARIB

    The George Institute

    patients with unresectable or metastatic HER2 negative breast cancer and a deleterious germline mutation in BRCA 1/2, ATM, BARD1, CHEK2, FANCC, PALB2, RAD51C, RAD51D, SLX4, XRCC2 or a homologous recombination deficiency

    phase 2 small molecule active

    1 trial

  2. PEMBROLIZUMAB, PEMBROLIZUMAB, CETUXIMAB, ENCORAFENIB

    Pfizer Australia Pty Ltd

    MSI-H/dMMR metastatic colorectal cancer

    phase 2 small molecule active

    1 trial

  3. PEMBROLIZUMAB, PM54

    Lacuna Pharma Pty Ltd

    Advanced malignancies

    phase 2 small molecule active

    1 trial

  4. PEMETREXED DISODIUM, PACLITAXEL, CARBOPLATIN, CISPLATIN, PACLITAXEL ALBUMIN-BOUND, Relatlimab, OPDIVO 10 mg/mL concentrate for solution for infusion.

    Bristol-Myers Squibb Australia Pty Ltd

    Non small Cell Lung cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  5. PEMETREXED DISODIUM, PEMBROLIZUMAB, PEMBROLIZUMAB, PACLITAXEL, GEN1055 DP, CISPLATIN, GEMCITABINE, PACLITAXEL ALBUMIN-BOUND, CARBOPLATIN

    Genmab A/S

    Malignant Solid Tumors

    phase 2 small molecule active

    1 trial

  6. PEMETREXED, Tusamitamab ravtansine, CISPLATIN, CARBOPLATIN, KEYTRUDA 25 mg/mL concentrate for solution for infusion

    Sanofi-aventis Healthcare Pty Ltd

    Cancer

    phase 2 small molecule active

    1 trial

  7. PENNVAX-GP

    INOVIO PHARMACEUTICALS, INC.

    HIV-1-infection

    phase 2 mab completed

    1 trial

  8. PEX168 or placebo

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes

    phase 2 small molecule completed

    1 trial

  9. PF-00547659

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  10. PF-00547659 SC injection

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  11. PF-03446962

    Pfizer

    Carcinoma, Hepatocellular

    phase 2 small molecule terminated

    1 trial

  12. PF-04236921 SC injection

    Pfizer

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  13. PF-04457845

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 2 small molecule completed

    1 trial

  14. PF-05190457

    BRIGHT MINDS BIOSCIENCES INC.

    Alcoholism

    phase 2 small molecule terminated

    1 trial

  15. PF-06650833

    Pfizer

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  16. PF-06835375

    Pfizer

    Primary Immune Thrombocytopenia

    phase 2 mab active

    1 trial

  17. PF-07248144, FULVESTRANT ZENTIVA 250 mg, solution injectable en seringue préremplie, PF-07248144

    Ningbo Cancer Hospital

    Adult patients with advanced hormone receptor positive (HR+), HER2- breast cancer after at least a first line of endocrine therapy combined with CDK4/6 inhibitor in the metastatic setting

    phase 2 small molecule active

    1 trial

  18. PF-07850327 round

    Pfizer Australia Pty Ltd

    ADVANCED OR METASTATIC BREAST CANCER

    phase 2 small molecule active

    1 trial

  19. PF-07868489

    Pfizer Australia Pty Ltd

    Pulmonary Arterial Hypertension

    phase 2 small molecule active

    1 trial

  20. PF-07915503, PF-07915503, PF-07915503, Etrasimod Arginine Blue, PF-07915503

    Pfizer Australia Pty Ltd

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  21. PF-08049820, PF-08049820, Placebo for PF-08049820

    Pfizer Australia Pty Ltd

    Atopic Dermatitis

    phase 2 small molecule active

    1 trial

  22. PF-08634404, YERVOY 5 mg/ml concentrate for solution for infusion

    Pfizer Australia Pty Ltd

    Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma

    phase 2 small molecule active

    1 trial

  23. PF614

    Ensysce Biosciences

    Acute Pain

    phase 2 small molecule completed

    1 trial

  24. PG2

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Stroke

    phase 2 small molecule completed

    1 trial

  25. PH-10

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial

  26. PH-10 (0.001% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial

  27. PH-10 (0.002% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial

  28. PH-10 (rose bengal disodium 0.001%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Plaque Psoriasis

    phase 2 small molecule terminated

    1 trial

  29. PH-797804

    Pfizer

    Pulmonary Disease, Chronic Obstructive

    phase 2 small molecule completed

    1 trial

  30. PH94B

    Vistagen Therapeutics

    Adjustment Disorder With Anxious Mood

    phase 2 small molecule completed

    1 trial

  31. PHE885

    Novartis Pharmaceuticals

    Multiple Myeloma

    phase 2 mab terminated

    1 trial

  32. PHITAH

    Lxo Ireland Designated Activity Company

    Basal Cell Carcinoma

    phase 2 mab active

    1 trial

  33. PI-88

    Biotech Pharmaceutical Co.,

    Lung Cancer

    phase 2 small molecule completed

    1 trial

  34. PI3K inhibitor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lymphoma, T-Cell

    phase 2 small molecule active

    1 trial

  35. PIK3CA inhibitor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Neoplasm

    phase 2 small molecule active

    1 trial

  36. PIO

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule terminated

    1 trial

  37. PIPE-307 Dose A

    Contineum Therapeutics

    Relapsing Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial

  38. PIPE-505

    Contineum Therapeutics

    Sensorineural Hearing Loss

    phase 2 small molecule completed

    1 trial

  39. PIPE-791 Dose A

    Contineum Therapeutics

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial

  40. PIROXICAM, LIDOCAINE HYDROCHLORIDE

    The George Institute

    lateral epicondylitis

    phase 2 small molecule active

    1 trial

  41. PIRTOBRUTINIB

    Fondazione Telethon ETS

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial

  42. PIVEKIMAB SUNIRINE

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia and other blood cancers

    phase 2 small molecule active

    1 trial

  43. PKN605, Placebo to PKN605 50 mg film-coated tablets

    Novartis Pharmaceuticals

    Atrial Fibrillation

    phase 2 small molecule active

    1 trial

  44. PL2200

    Protalix BioTherapeutics

    Gastroduodenal Ulceration

    phase 2 small molecule completed

    1 trial

  45. PL3100

    Protalix BioTherapeutics

    Gastroduodenal Ulcerations

    phase 2 small molecule completed

    1 trial

  46. PLACEBO, BELTAVAC polymerized grass mix, BELTAVAC polymerized grass mix, -

    Lacuna Pharma Pty Ltd

    allergic rhinoconjunctivitis caused due to exposure to pollen grasses

    phase 2 small molecule active

    1 trial

  47. PLACEBO, BELTAVAC polymerized grass mix, BELTAVAC polymerized grass mix, BELTAVAC polymerized grass mix, -

    Lacuna Pharma Pty Ltd

    Allergic rhinoconjunctivitis caused due to exposure to pollen grasses

    phase 2 small molecule active

    1 trial

  48. PLD and Carboplatin

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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