πŸ‡ΊπŸ‡Έ FDA

Intelligence Β· Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 93 of 99

  1. [14C]-BMS986504 Mass Balance Study in Patients with Advanced Solid Tumors with Homozygous MTAP Deletion

    Bristol-Myers Squibb Australia Pty Ltd

    Advanced Solid Tumors

    phase 1 other active

    1 trial

  2. [14C]-CORT113176

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  3. [14C]-CORT125134

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  4. [14C]-CRN00808

    Crinetics Pharmaceuticals Europe GmbH

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  5. [14C]-DNL343

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  6. [14C]-Danicopan

    Alexion Europe SAS

    Healthy

    phase 1 small molecule completed

    1 trial

  7. [14C]-EDG-7500

    Edgewise Therapeutics

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  8. [14C]-GSK961081 solution for IV infusion

    Theravance Biopharma Ireland Umited

    Pulmonary Disease, Chronic Obstructive

    phase 1 small molecule completed

    1 trial

  9. [14C]-HEC585

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  10. [14C]-LX4211

    LEXICON PHARMACEUTICALS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  11. [14C]-Larotinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male Volunteers

    phase 1 small molecule completed

    1 trial

  12. [14C]-NV-5138

    SUPERNUS PHARMACEUTICALS, INC.

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  13. [14C]-PC14586

    PMV Pharmaceuticals

    Healthy Male Volunteers

    phase 1 small molecule completed

    1 trial

  14. [14C]-Paxalisib Capsule

    KAZIA THERAPEUTICS LTD

    Healthy

    phase 1 small molecule completed

    1 trial

  15. [14C]-TAK-385 Oral Solution

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  16. [14C]-TAK-954

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  17. [14C]-TVB-2640

    Sagimet Biosciences

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  18. [14C]-benzo[a]pyrene

    NORTHWEST BIOTHERAPEUTICS INC

    Environmental Exposure

    phase 1 small molecule completed

    3 trials

  19. [14C]-etrumadenant

    Arcus Biosciences

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  20. [14C]-olinciguat

    Cyclerion Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  21. [14C]-praliciguat

    Cyclerion Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  22. [14C]-rencofilstat 225mg

    Hepion Pharmaceuticals

    NASH With Fibrosis

    phase 1 small molecule completed

    1 trial

  23. [14C]-tebapivat

    Agios Netherlands B.V.

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  24. [14C]Clifutinib

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male

    phase 1 small molecule completed

    1 trial

  25. [14C]HSK7653

    The First People's Hospital of Lianyungang

    Type II Diabetes

    phase 1 small molecule completed

    1 trial

  26. [14C]IDV184001AN

    Indivior Pty Ltd

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  27. [14C]SSS17

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Subjects (HS)

    phase 1 small molecule active

    1 trial

  28. [14C]TGRX-326

    The First People's Hospital of Lianyungang

    Non Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  29. [177Lu]Lu-XT117

    The First People's Hospital of Lianyungang

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  30. [18F]-Ξ±vΞ²6-BP

    United Therapeutics Europe Ltd

    Lung Cancer

    phase 1 small molecule active

    1 trial

  31. [18F]APN-1607

    The First People's Hospital of Lianyungang

    Alzheimer Disease

    phase 1 small molecule active

    1 trial

  32. [18F]F-AraG

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cancer

    phase 1 small molecule active

    1 trial

  33. [18F]FP-R01-MG-F2

    PLIANT THERAPEUTICS, INC.

    Idiopathic Pulmonary Fibrosis

    phase 1 small molecule completed

    1 trial

  34. [18F]fluoro-PEG-folate PET/CT scan

    BRIGHT MINDS BIOSCIENCES INC.

    Epithelial Ovarian Cancer

    phase 1 other terminated

    1 trial

  35. [203Pb]VMT-Ξ±-NET

    Perspective Therapeutics

    Neuroendocrine Tumor Grade 2

    phase 1 small molecule active

    1 trial

  36. [203Pb]VMT01

    Perspective Therapeutics

    Melanoma (Skin)

    phase 1 small molecule completed

    1 trial

  37. [212Pb] VMT-Ξ±-NET

    Perspective Therapeutics

    Neuroendocrine Tumors

    phase 1 small molecule active

    1 trial

  38. [225Ac]Ac-AKY-1189 (therapeutic)

    Aktis Oncology

    Urothelial Carcinoma Bladder

    phase 1 small molecule active

    1 trial

  39. [225Ac]Ac-AKY-2519 (therapeutic)

    Aktis Oncology

    Castration Resistant Metastatic Prostate Cancer

    phase 1 small molecule active

    1 trial

  40. [68Ga]Ga-PentixaFor

    CERO THERAPEUTICS HOLDINGS, INC.

    triple-negative breast cancer

    phase 1 small molecule active

    1 trial

  41. [68Ga]Ga-Sa-DABI-4

    The First People's Hospital of Lianyungang

    Stimulator of Interferon Gene

    phase 1 small molecule active

    1 trial

  42. [68Ga]MLN6907

    Takeda

    Imaging of Solid Gastrointestinal Tumors

    phase 1 small molecule completed

    1 trial

  43. [F18]-ASEM (3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-[18F]fluorodibenzo[b,d]thiophene 5,5-dioxide)

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 1 small molecule completed

    1 trial

  44. [^14C]-alisertib

    Takeda

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  45. a 60 mg dose of the hydrocodone bitartrate extended-release tablet administered as either two 30-mg tablets (Treatment A) or one 60-mg tablet (Treatment B).

    Teva Pharma GmbH

    Pain

    phase 1 small molecule completed

    1 trial

  46. acetylsalicylic acid

    United Therapeutics Europe Ltd

    Precancerous Condition

    phase 1 small molecule completed

    1 trial

  47. acupuncture

    United Therapeutics Europe Ltd

    Migraine Headaches

    phase 1 other completed

    1 trial

  48. administration of UI018

    United Therapeutics Europe Ltd

    Hyperlipemia, Mixed

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources Β· All pipeline programs

Drug approvals, clinical trials, M&A, event intelligence, and company updates β€” weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.