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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 92 of 99

  1. ZB001 for injection

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  2. ZB002

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule active

    1 trial

  3. ZB004

    Zenas BioPharma

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  4. ZE46-0134

    Lomond Therapeutics Holdings

    AML With Gene Mutations

    phase 1 small molecule active

    1 trial

  5. ZF874

    Centessa Pharmaceuticals plc

    Alpha1 Anti-Trypsin Deficiency

    phase 1 small molecule terminated

    1 trial

  6. ZFN modified T cells

    SANGAMO THERAPEUTICS, INC

    HIV

    phase 1 mab completed

    1 trial

  7. ZG0895 Hydrochloride for Injection

    Suzhou Zelgen Biopharmaceuticals Co.,Ltd

    Advanced Solid Tumor

    phase 1 small molecule active

    1 trial

  8. ZIO-101

    Alaunos Therapeutics

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  9. ZIO-101 (Darinaparsin)

    Alaunos Therapeutics

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  10. ZIO-101 (Darinaparsin)

    Alaunos Therapeutics

    Acute Leukemia

    phase 1 small molecule completed

    1 trial

  11. ZIO-101-C (Darinaparsin)

    Alaunos Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  12. ZIO-101-C (Darinaparsin)

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  13. ZIO-201

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  14. ZIO-201-T and doxorubicin

    Alaunos Therapeutics

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  15. ZN-c3

    Zentalis Pharmaceuticals

    Metastatic Colorectal Cancer

    phase 1 small molecule terminated

    1 trial

  16. ZN-c3

    Zentalis Pharmaceuticals

    Tumors

    phase 1 small molecule terminated

    1 trial

  17. ZN-d5

    Zentalis Pharmaceuticals

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  18. ZN-d5

    Zentalis Pharmaceuticals

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  19. ZW25 (Zanidatamab)

    Jazz Pharmaceuticals Ireland Limited

    HER2-expressing Cancers

    phase 1 small molecule completed

    1 trial

  20. Zaleplon 10 mg Capsules

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  21. Zanubrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  22. Zasocitinib

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  23. Zejula 100 mg film-coated tablets, Zejula 100 mg film-coated tablets, JEMPERLI 500 mg concentrate for solution for infusion

    GlaxoSmithKline

    Solid Tumours

    phase 1 small molecule active

    1 trial

  24. Ziftomenib

    Kura Oncology

    AML

    phase 1 small molecule active

    1 trial

  25. Ziftomenib

    Kura Oncology

    Relapsed/Refractory KMT2A-r Acute Leukemia

    phase 1 small molecule active

    1 trial

  26. Ziftomenib

    Kura Oncology

    Refractory Acute Leukemia

    phase 1 small molecule active

    1 trial

  27. Ziftomenib

    Kura Oncology

    Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  28. Ziftomenib

    Kura Oncology

    KMT2A-rearranged

    phase 1 small molecule active

    1 trial

  29. Ziftomenib, Ziftomenib, Cytarabine 20 mg/ml Solution for Injection/Infusion, Fludarabine phosphate 25 mg/ml Concentrate for Solution for Injection or Infusion, Ziftomenib, Cytarabine 20 mg/ml Solution for Injection/Infusion, Solu-Cortef Powder for Solution for Injection or Infusion 100 mg

    AXIM BIOTECHNOLOGIES, INC.

    Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Acute Lymphocytic Leukemia

    phase 1 small molecule active

    1 trial

  30. Zimberelimab

    Arcus Biosciences

    Head and Neck Cancer

    phase 1 small molecule terminated

    1 trial

  31. Zimberelimab

    Arcus Biosciences

    Glioblastoma

    phase 1 small molecule active

    1 trial

  32. Zithromax®

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  33. Zolmitriptan intranasal.

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  34. Zoloft® 100 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  35. Zolpidem 10 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  36. Zunsemetinib

    Aclaris Therapeutics

    Metastatic Pancreatic Ductal Adenocarcinoma

    phase 1 small molecule active

    1 trial

  37. [11C]APP311

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use Disorder

    phase 1 small molecule active

    1 trial

  38. [11C]CPPC Injection

    Chongqing Precision Biotech Co., Ltd

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule terminated

    1 trial

  39. [11C]OMAR

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Control

    phase 1 small molecule active

    1 trial

  40. [123I] IBVM and SPECT imaging

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 1 small molecule completed

    1 trial

  41. [14C-ETC-1002]

    Esperion Therapeutics

    Hyperlipidemia

    phase 1 small molecule completed

    1 trial

  42. [14C] Antaitavir Hasophate

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Male Subjects

    phase 1 small molecule completed

    1 trial

  43. [14C] BIIB122 ([14C] DNL151)

    Denali Therapeutics

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  44. [14C] HRS-9190

    Jian Li

    Healthy Adult Male

    phase 1 small molecule active

    1 trial

  45. [14C] Subasumstat

    Takeda

    Solid Tumors

    phase 1 small molecule terminated

    1 trial

  46. [14C] Yiqibuvir

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Male Subjects

    phase 1 small molecule completed

    1 trial

  47. [14C]- Rongliflozin

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Healthy Adult Male Volunteers

    phase 1 small molecule completed

    1 trial

  48. [14C]-AG-120

    Agios Netherlands B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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