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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. TQF3250 placebo

    Chia Tai Tianqing Pharmaceutical Group Co.,

    Hyperglycemia

    phase 1 small molecule active

    1 trial

  2. TRIN2755

    BRIGHT MINDS BIOSCIENCES INC.

    Neoplasms

    phase 1 small molecule active

    1 trial

  3. TRK-100STP (BERASUS LA)

    Astellas Pharma Inc

    Healthy

    phase 1 small molecule completed

    1 trial

  4. TRU-016

    Aptevo Therapeutics

    B-cell Small Lymphocytic Lymphoma Recurrent

    phase 1 small molecule completed

    1 trial

  5. TRU-016 (anti-CD37 protein therapeutic)

    Aptevo Therapeutics

    Chronic Lymphocytic Leukemia (CLL)

    phase 1 small molecule completed

    1 trial

  6. TRUQAP 200 mg film-coated tablets, Faslodex 250 mg solution for injection., TRUQAP 160 mg film-coated tablets, PACLITAXEL, IMFINZI 50 mg/mL concentrate for solution for infusion., Capecitabine Accord 500 mg film-coated tablets, Capecitabine Accord 150 mg film-coated tablets, DS-8201a, Arimidex® 1 mg film-coated tablets

    AstraZeneca AB

    Metastatic Breast Cancer

    phase 1 small molecule active

    1 trial

  7. TSB-9-W1

    Biotech Pharmaceutical Co.,

    Metastatic Colorectal Cancer

    phase 1 small molecule completed

    1 trial

  8. TSC-204-A0201

    TScan Therapeutics

    Head and Neck Cancer

    phase 1 mab active

    1 trial

  9. TTI-101

    Tvardi Therapeutics

    Breast Cancer

    phase 1 small molecule completed

    2 trials

  10. TTI-101

    Tvardi Therapeutics

    Pancreatic Cancer

    phase 1 small molecule active

    1 trial

  11. TTP4000

    vTv Therapeutics

    Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  12. TTP607

    vTv Therapeutics

    Advanced Cancers

    phase 1 small molecule terminated

    1 trial

  13. TTX-MC138-NODAGA-Cu64

    Transcode Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  14. TV-45070

    Teva Pharma GmbH

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  15. TV-46046

    Teva Pharma GmbH

    Contraception

    phase 1 small molecule completed

    2 trials

  16. TV-46046 - 400 mg/mL

    Teva Pharma GmbH

    Pregnancy

    phase 1 small molecule completed

    1 trial

  17. TV46017

    Teva Pharma GmbH

    Chronic Obstructive Pulmonary Disease (COPD

    phase 1 small molecule terminated

    1 trial

  18. TV48108

    Teva Pharma GmbH

    Chronic Obstructive Pulmonary Disease

    phase 1 small molecule terminated

    1 trial

  19. TVB-2640

    Sagimet Biosciences

    Prostatic Neoplasms, Castration-Resistant

    phase 1 small molecule active

    1 trial

  20. TVB-2640

    Sagimet Biosciences

    Solid Malignant Tumor

    phase 1 small molecule completed

    1 trial

  21. TVB-2640 - 50 mg

    Sagimet Biosciences

    Non-alcoholic Steatohepatitis

    phase 1 small molecule completed

    1 trial

  22. TVB-3567

    Sagimet Biosciences

    Acne

    phase 1 small molecule active

    1 trial

  23. TYRA-300-B01

    Tyra Biosciences

    Healthy

    phase 1 small molecule active

    1 trial

  24. TYRA-430

    Tyra Biosciences

    Metastatic Hepatocellular Carcinoma

    phase 1 small molecule active

    1 trial

  25. Ta-NPs (2% Tumor Volume)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Recurrent Retroperitoneal Soft Tissue Sarcoma

    phase 1 mab active

    1 trial

  26. Tabalumab

    Eli Lilly and Company

    Multiple Myeloma

    phase 1 mab completed

    1 trial

  27. Tacrolimus

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  28. Tacrolimus

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  29. Tafamidis round 2, Tafamidis round 1, Tafamidis oblong

    Pfizer Australia Pty Ltd

    aransthyretin amyloid cardiomyopathy

    phase 1 small molecule active

    1 trial

  30. Takeda Brentuximab; Molecular Imaging of Zirconium-89-labeled Brentuximab as a Tool to Investigate brentuximab biodistribution in CD30-positive Lymphoma

    Disc Medicine

    Patients with stage II-IV high risk diffuse large B-cell lymphoma, defined as international prognostic index > 2, Lymphoma

    phase 1 other active

    1 trial

  31. Takeda's Tetravalent Dengue Vaccine Candidate (TDV)

    Takeda

    Healthy

    phase 1 mab completed

    1 trial

  32. Talabostat Mesylate

    BioXcel Therapeutics

    Cancer of Pancreas

    phase 1 small molecule terminated

    1 trial

  33. Talampanel

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  34. Talampanel (non-radiolabeled), [14C] Talampanel

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule terminated

    1 trial

  35. Talazoparib

    BioMarin Pharmaceutical Australia Pty Ltd

    Childhood Solid Tumors

    phase 1 small molecule completed

    1 trial

  36. Tamsulosin

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  37. Tamsulosin formulation-A

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Healthy

    phase 1 small molecule completed

    1 trial

  38. Target CD7 CAR-T cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    T-cell Acute Lymphoblastic Leukemia

    phase 1 mab terminated

    1 trial

  39. Targeted CEA CAR-T

    Chongqing Precision Biotech Co., Ltd

    Advanced Lung Cancer

    phase 1 mab active

    4 trials

  40. Tarlatamab

    BEONE MEDICINES AUS PTY LTD

    Extensive Stage Small Cell Lung Cancer

    phase 1 small molecule active

    1 trial

  41. Tarlatamab

    Amgen

    Neuroendocrine Prostate Cancer

    phase 1 small molecule completed

    1 trial

  42. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  43. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    REM Behavior Disorder

    phase 1 small molecule terminated

    1 trial

  44. Tasimelteon

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy Volunteers

    phase 1 small molecule completed

    4 trials

  45. Tasimelteon Oral Capsule

    Vanda Pharmaceuticals Netherlands B.V.

    Healthy

    phase 1 small molecule completed

    1 trial

  46. Tasocitinib 10 mg oral tablet

    Pfizer

    Healthy

    phase 1 small molecule completed

    1 trial

  47. Tcrx T cell

    TScan Therapeutics

    Gastric Cancer

    phase 1 mab active

    1 trial

  48. Tebipenem Pivoxil Hydrobromide

    Spero Therapeutics

    Diabetes

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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