Intelligence Β· Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. TAK-491

    Takeda

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial
  2. TAK-510

    Takeda

    Healthy Participants

    phase 1 small molecule completed

    1 trial
  3. TAK-536

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  4. TAK-536

    Takeda

    Japanese Healthy Adult Male Participants

    phase 1 small molecule completed

    1 trial
  5. TAK-536 Tablet

    Takeda

    Japanese Healthy Adult Males

    phase 1 small molecule completed

    1 trial
  6. TAK-536TCH

    Takeda

    Hypertension

    phase 1 small molecule completed

    1 trial
  7. TAK-573

    Teva Pharma GmbH

    Relapsed and/or Refractory Multiple Myeloma

    phase 1 small molecule terminated

    1 trial
  8. TAK-580

    Takeda

    Melanoma

    phase 1 small molecule terminated

    1 trial
  9. TAK-648

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  10. TAK-648

    Takeda

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial
  11. TAK-648 Tablet

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  12. TAK-653

    NEUROCRINE BIOSCIENCES INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  13. TAK-653 Placebo

    NEUROCRINE BIOSCIENCES INC

    Depressive Disorder

    phase 1 small molecule completed

    1 trial
  14. TAK-659

    Takeda

    Lymphoma, Non-Hodgkin

    phase 1 small molecule terminated

    1 trial
  15. TAK-659

    Nektar Therapeutics UK Limited

    Lymphoma, Non-Hodgkin

    phase 1 small molecule terminated

    1 trial
  16. TAK-671

    Takeda

    Coronavirus Disease

    phase 1 small molecule terminated

    1 trial
  17. TAK-676

    Takeda

    Head and Neck Squamous Cell Carcinoma

    phase 1 small molecule completed

    1 trial
  18. TAK-755

    Takeda

    Sickle Cell Disease

    phase 1 small molecule completed

    1 trial
  19. TAK-781

    Takeda

    Healthy Volunteers

    phase 1 small molecule active

    1 trial
  20. TAK-788

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    3 trials
  21. TAK-792 30 mg

    Takeda

    Healthy Male Adults Participants

    phase 1 small molecule completed

    1 trial
  22. TAK-828

    Takeda

    Healthy Volunteers

    phase 1 small molecule terminated

    1 trial
  23. TAK-828

    Takeda

    Dose Finding Study

    phase 1 small molecule completed

    1 trial
  24. TAK-831

    NEUROCRINE BIOSCIENCES INC

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials
  25. TAK-831

    NEUROCRINE BIOSCIENCES INC

    Healthy

    phase 1 small molecule completed

    1 trial
  26. TAK-831 Oral Suspension

    NEUROCRINE BIOSCIENCES INC

    Schizophrenia, Cerebellar Ataxia

    phase 1 small molecule terminated

    1 trial
  27. TAK-831 Oral Tablet

    NEUROCRINE BIOSCIENCES INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  28. TAK-831 T2

    NEUROCRINE BIOSCIENCES INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  29. TAK-831 Tablet T2

    NEUROCRINE BIOSCIENCES INC

    Healthy

    phase 1 small molecule completed

    1 trial
  30. TAK-861, TAK-861, TAK-861

    Takeda

    Narcolepsy with Cataplexy (Narcolepsy Type 1)

    phase 1 small molecule active

    1 trial
  31. TAK-875 and Glimepiride

    Takeda

    Pharmacokinetics

    phase 1 small molecule completed

    1 trial
  32. TAK-881

    Takeda

    Healthy Volunteers

    phase 1 mab completed

    3 trials
  33. TAK-906

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    3 trials
  34. TAK-906

    Takeda

    Japanese Healthy Adult Male Participants

    phase 1 small molecule completed

    1 trial
  35. TAK-906 Maleate

    Takeda

    Healthy Participants

    phase 1 small molecule completed

    1 trial
  36. TAK-906 Oral Capsule

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  37. TAK-915

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  38. TAK-915 suspension

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  39. TAK-925

    Takeda

    Healthy Participants and Patients With Narcolepsy

    phase 1 small molecule completed

    1 trial
  40. TAK-925

    Takeda

    Obstructive Sleep Apnea

    phase 1 small molecule completed

    1 trial
  41. TAK-925

    Takeda

    Idiopathic Hypersomnia

    phase 1 small molecule completed

    1 trial
  42. TAK-925

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  43. TAK-925

    Takeda

    Healthy Participants

    phase 1 small molecule completed

    1 trial
  44. TAK-931

    Takeda

    Nonhematologic Neoplasms, Advanced

    phase 1 small molecule completed

    1 trial
  45. TAK-931 PIC

    Takeda

    Neoplasms, Advanced Solid

    phase 1 small molecule completed

    1 trial
  46. TAK-935

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial
  47. TAK-935

    Takeda

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial
  48. TAK-935

    Takeda

    Epilepsy, Molecular Mechanisms of Pharmalogical Action, Protective Agents

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources Β· All pipeline programs