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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. Reslizumab IV

    Teva Pharma GmbH

    Absolute Bioavailability

    phase 1 small molecule completed

    1 trial

  2. Retifanlimab

    ACTUATE THERAPEUTICS, INC.

    Pancreatic Adenocarcinoma

    phase 1 small molecule active

    1 trial

  3. Revumenib

    Syndax Pharmaceuticals

    Blinatumomab

    phase 1 small molecule active

    1 trial

  4. Revumenib

    Syndax Pharmaceuticals

    Refractory Acute Myeloid Leukemia

    phase 1 small molecule active

    1 trial

  5. Revumenib

    Syndax Pharmaceuticals

    Acute Leukemia

    phase 1 small molecule completed

    1 trial

  6. Revumenib

    Syndax Pharmaceuticals

    Relapsed/Refractory Leukemias

    phase 1 small molecule completed

    1 trial

  7. Ribavirin 200 mg tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  8. Rilonacept

    Regeneron UK Limited

    Autoimmune Neurosensory Hearing Loss (ANSHL)

    phase 1 small molecule active

    1 trial

  9. Risperidone

    CORCEPT THERAPEUTICS INC

    Healthy

    phase 1 small molecule completed

    1 trial

  10. Risperidone

    The First People's Hospital of Lianyungang

    Schizophrenia

    phase 1 small molecule active

    1 trial

  11. Risperidone

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  12. Ritonavir Tablet 100mg

    The First People's Hospital of Lianyungang

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  13. Ritonavir for cycle1 and NORVIR for cycle 2

    The First People's Hospital of Lianyungang

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  14. Rituximab

    The First People's Hospital of Lianyungang

    Diffuse Large B-cell Lymphoma Recurrent

    phase 1 small molecule active

    1 trial

  15. Rituximab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Carcinoma

    phase 1 small molecule completed

    1 trial

  16. Roflumilast

    Takeda

    Schizophrenia

    phase 1 small molecule completed

    1 trial

  17. Rongliflozin

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  18. Ropinirole HCl 0.25 mg Tablets

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    2 trials

  19. Rose bengal disodium

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Neuroendocrine Tumors Metastatic to the Liver

    phase 1 small molecule active

    1 trial

  20. Rowasa® 4 gm/60 mL Rectal Enema

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  21. Rugonersen

    Hoffmann-La Roche

    Angelman Syndrome (AS)

    phase 1 small molecule active

    1 trial

  22. S 55746

    Servier Laboratories (Aust.) Pty.

    Chronic Lymphocytic Leukaemia (CLL)

    phase 1 small molecule completed

    1 trial

  23. SA55 Injection

    Sinovac Research and Development Co.,

    COVID-19

    phase 1 small molecule active

    1 trial

  24. SA55 nasal spray

    Sinovac Research and Development Co.,

    COVID-19

    phase 1 small molecule active

    1 trial

  25. SAB-176

    SAB Biotherapeutics

    Influenza Type A

    phase 1 mab completed

    1 trial

  26. SAB-185

    SAB Biotherapeutics

    COVID-19

    phase 1 mab active

    2 trials

  27. SAB-301

    SAB Biotherapeutics

    Middle East Respiratory Syndrome Coronavirus

    phase 1 mab completed

    1 trial

  28. SAGE-718

    SUPERNUS PHARMACEUTICALS, INC.

    Healthy Volunteer

    phase 1 small molecule completed

    3 trials

  29. SAGE-904

    SUPERNUS PHARMACEUTICALS, INC.

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  30. SAM-315

    Wyeth is now a wholly owned subsidiary of Pfizer

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  31. SAR231893 (REGN668)

    Regeneron UK Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  32. SAR231893 (REGN668) DP1

    Regeneron UK Limited

    Healthy

    phase 1 mab completed

    1 trial

  33. SAR441000

    Atrium Therapeutics

    Metastatic Neoplasm

    phase 1 small molecule terminated

    1 trial

  34. SAR447971 first-in-human study

    Sanofi-aventis Healthcare Pty Ltd

    Hidradenitis

    phase 1 other active

    1 trial

  35. SAR448501

    Sanofi Pasteur

    B-cell Non Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  36. SB-659032

    GlaxoSmithKline

    Atherosclerosis

    phase 1 small molecule completed

    1 trial

  37. SB-728-T

    SANGAMO THERAPEUTICS, INC

    HIV Infection

    phase 1 gene therapy completed

    1 trial

  38. SB-728mR-HSPC Infusion 3 days following busulfan conditioning

    SANGAMO THERAPEUTICS, INC

    HIV

    phase 1 gene therapy active

    1 trial

  39. SB-FIX

    SANGAMO THERAPEUTICS, INC

    Hemophilia B

    phase 1 mab terminated

    1 trial

  40. SBP-9330

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 1 small molecule completed

    1 trial

  41. SC HYLENEX and Ceftriaxone

    HALOZYME THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  42. SC-DARIC33

    Regeneron UK Limited

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  43. SC262

    Sana Biotechnology

    Non Hodgkin's Lymphoma

    phase 1 small molecule active

    1 trial

  44. SC291

    Sana Biotechnology

    Non Hodgkin Lymphoma

    phase 1 small molecule active

    1 trial

  45. SC291

    Sana Biotechnology

    Lupus Erythematosus

    phase 1 mab active

    1 trial

  46. SCT-001 CAR-T cells

    Shanghai University of Traditional Chinese Medicine

    Ovarian Cancer

    phase 1 mab active

    1 trial

  47. SCT510

    The First People's Hospital of Lianyungang

    Healthy

    phase 1 small molecule completed

    1 trial

  48. SD-809

    Teva Pharma GmbH

    TOURETTE SYNDROME

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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