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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 73 of 99

  1. REGN7999

    Regeneron UK Limited

    Healthy

    phase 1 small molecule completed

    1 trial

  2. REGN846

    Regeneron UK Limited

    Healthy

    phase 1 mab completed

    1 trial

  3. REGN88

    Regeneron UK Limited

    Rheumatoid Arthritis

    phase 1 mab completed

    3 trials

  4. REGN9035

    Regeneron UK Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  5. REGN9533

    Regeneron UK Limited

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  6. REGN9933

    Regeneron UK Limited

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  7. REL-1017

    RELMADA THERAPEUTICS, INC.

    Neuropathic Pain

    phase 1 small molecule completed

    2 trials

  8. REN001

    OnKure Therapeutics

    McArdle Disease

    phase 1 small molecule completed

    1 trial

  9. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    KRAS Mutant Metastatic Colorectal Cancer

    phase 1 mab completed

    1 trial

  10. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Malignant Glioma

    phase 1 mab completed

    1 trial

  11. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Pancreatic Adenocarcinoma

    phase 1 mab completed

    1 trial

  12. REOLYSIN®

    ONCOLYTICS BIOTECH INC

    Muscle-invasive Transitional Cell Carcinoma of the Bladder

    phase 1 mab terminated

    1 trial

  13. RESTART; Autologous Transplantation of Adult Salivary Gland Stem Cells to Restore Submandibular Gland Function after Radiotherapy

    Disc Medicine

    Patients operated with curative intend for head and neck cancer with an indication for bilateral postoperative radiotherapy, with or without chemotherapy.

    phase 1 other active

    1 trial

  14. RJK-RT2831 dose-escalation phase Ia

    Nanjing Zenshine Pharmaceuticals

    Hematologic Malignancies

    phase 1 small molecule active

    1 trial

  15. RJMty19 (CD19-CAR-DNT cells)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    B-cell Non-Hodgkin's Lymphoma

    phase 1 mab active

    1 trial

  16. RLY-5836

    Relay Therapeutics

    PIK3CA Mutation

    phase 1 small molecule completed

    1 trial

  17. RLY-8161

    Relay Therapeutics

    NRAS Mutation

    phase 1 small molecule active

    1 trial

  18. RM-493

    Rhythm Pharmaceuticals Netherlands B.V.

    Overweight

    phase 1 small molecule completed

    1 trial

  19. RMC-4630

    Revolution Medicines

    Solid Tumors

    phase 1 small molecule active

    1 trial

  20. RMC-5127

    Revolution Medicines

    Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial

  21. RMC-5552

    Revolution Medicines

    Glioblastoma

    phase 1 small molecule terminated

    1 trial

  22. RMC-5552

    Revolution Medicines

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  23. RMC-6291

    Revolution Medicines

    Non-Small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    2 trials

  24. RMC-9805

    Revolution Medicines

    Non-small Cell Lung Cancer (NSCLC)

    phase 1 small molecule active

    1 trial

  25. RO5323441

    Hoffmann-La Roche

    Carcinoma, Hepatocellular

    phase 1 small molecule completed

    1 trial

  26. RO5503781

    Hoffmann-La Roche

    Neoplasms

    phase 1 small molecule completed

    1 trial

  27. RO5503781 MBP

    Hoffmann-La Roche

    Myelogenous Leukemia, Acute

    phase 1 small molecule completed

    1 trial

  28. RO7119929

    Hoffmann-La Roche

    Carcinoma, Hepatocellular

    phase 1 small molecule completed

    1 trial

  29. RO7507062

    Hoffmann-La Roche

    Systemic Lupus Erythematosus

    phase 1 small molecule active

    1 trial

  30. RP-A601

    Rocket Pharmaceuticals B.V.

    PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)

    phase 1 gene therapy active

    1 trial

  31. RP-A701 is a recombinant viral vector composed of an AAV serotype rh.74 (AAVrh.74) capsid encapsulating the transgene, BCL2-associated Athanogene 3 (BAG3)

    Rocket Pharmaceuticals B.V.

    Dilated Cardiomyopathy (DCM)

    phase 1 gene therapy active

    1 trial

  32. RP-L401

    Rocket Pharmaceuticals B.V.

    Infantile Malignant Osteopetrosis

    phase 1 mab terminated

    1 trial

  33. RT-102 (80 μg)

    Rani Therapeutics Holdings

    Healthy Volunteers

    phase 1 other completed

    1 trial

  34. RT-114 is the RaniPill capsule with PG-102 for the treatment of obesity

    Rani Therapeutics Holdings

    Obesity

    phase 1 other active

    1 trial

  35. RTI-336

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 1 small molecule terminated

    1 trial

  36. RUC-4 Compound

    Chongqing Precision Biotech Co., Ltd

    Coronary Disease

    phase 1 small molecule completed

    1 trial

  37. Rabeprazole Sodium 10mg

    Yung NA

    Gastroesophageal Reflux Disease

    phase 1 small molecule completed

    1 trial

  38. Radiation: 18F-AlF-FAPi-04

    Sichuan Provincial People's Hospital

    Tumor, Solid

    phase 1 small molecule active

    1 trial

  39. Radiolabeled Prucalopride Succinate

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  40. Radiolabeled SPD557

    Takeda

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  41. Radiolabeled SPD602 (FBS0701, SSP-004184)

    Takeda

    Healthy

    phase 1 small molecule completed

    1 trial

  42. Radiolabelled Diclofenac Tablet A

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule completed

    1 trial

  43. Radiolabelled T4 Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Pain

    phase 1 small molecule completed

    1 trial

  44. Ramelteon 8 mg

    Takeda

    Insomnia

    phase 1 small molecule completed

    1 trial

  45. Ramipril 10 mg capsule

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    3 trials

  46. Ramipril tablet 10 mg

    LIGAND PHARMACEUTICALS INC

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  47. Ramipril/Hydrochlorothiazide tablet 10 mg/25 mg

    LIGAND PHARMACEUTICALS INC

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  48. Randomised, bioequivalence clinical trial of atorvastatin 80 mg capsules vs atorvastatin 80 mg film-coated tablets, after a single oral dose administration to healthy volunteers under fasting conditions in crossover replicated design.

    Laboratorios Tillomed Spain S.L.U

    Hypercholesterolaemia, Prevention of cardiovascular disease

    phase 1 other active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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