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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. Multi-media WINGS

    BRIGHT MINDS BIOSCIENCES INC.

    Intimate Partner Violence

    phase 1 other completed

    1 trial

  2. Multiple Ascending Dose Study of LY4256984 in Participants with Sporadic Amyotrophic Lateral Sclerosis

    Eli Lilly Co.

    Sporadic Amyotrophic Lateral Sclerosis

    phase 1 other active

    1 trial

  3. Multiple Ascending Doses of BMS-986326 in Participants with Discoid Lupus Erythematosus, Subacute Cutaneous Lupus Erythematosus, or Systemic Lupus Erythematosus

    Bristol-Myers Squibb Australia Pty Ltd

    Subacute Cutaneous Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Lupus Erythematosus

    phase 1 other active

    1 trial

  4. Multiple Dose Study of RO7795068 and its effect on Gastric Emptying, and on PK of Oral Contraceptives

    Hoffmann-La Roche

    Healthy Overweight or Obese

    phase 1 other active

    1 trial

  5. Multiple-Ascending Doses of 2-Methoxyestradiol in Healthy Non-Pregnant Female Participants.

    Laboratorios Tillomed Spain S.L.U

    No medical condition.

    phase 1 other active

    1 trial

  6. Multiple-Dose Bioequivalence of Mirabegron 50 mg Prolonged-Release Tablets in Healthy Participants Under Fasting Conditions.

    Laboratorios Tillomed Spain S.L.U

    No medical condition.

    phase 1 other active

    1 trial

  7. Multiple-Dose Study in Healthy Participants Under Fasting Conditions to Evaluate the Bioequivalence of One Film-Coated Mini-Tablet of Indapamide SR 1.5 mg versus One Film-Coated Tablet of Indapamide SR 1.5 mg and to Compare the Bioavailability of One Film-Coated Mini-Tablet of Indapamide SR 1.5 mg versus One Film-Coated Tablet of Indapamide IR 2.5 mg.

    The George Institute

    No medical condition.

    phase 1 other active

    1 trial

  8. Multiple-Dose Study on the Bioequivalence of One Tablet of Gliclazide MR 120 mg (S005190) and Two Tablets of Gliclazide MR 60 mg (Diaprel® MR) in Healthy Participants under Fed Conditions.

    The George Institute

    No medical condicion.

    phase 1 other active

    1 trial

  9. Multiple-dose, open-label, laboratory blinded, randomized, 2-period, 2-sequence, crossover, steady-state bioequivalence study comparing the Test Product Naproxen sodium 660 mg modified release tablets with the Reference Product Actromadol 660 mg Modified-Release tablets in healthy adult male and female subjects under fed conditions.

    Laboratorios Tillomed Spain S.L.U

    No medical condition

    phase 1 other active

    1 trial

  10. Mycophenolate Mofetil

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    4 trials

  11. Mycophenolate Mofetil

    BRIGHT MINDS BIOSCIENCES INC.

    Hematopoietic Stem Cell Transplantation

    phase 1 small molecule active

    1 trial

  12. N-Acetylcysteine

    United Therapeutics Europe Ltd

    Mitochondrial Disease

    phase 1 small molecule active

    1 trial

  13. N-acetyl cysteine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 1 small molecule completed

    1 trial

  14. N-acetylcysteine

    Ultragenyx UK Limited

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  15. N-acetylcysteine, NAC, and calcitriol

    United Therapeutics Europe Ltd

    HIE - Perinatal Hypoxic - Ischemic Encephalopathy

    phase 1 small molecule completed

    1 trial

  16. NAL ER

    Trevi Therapeutics

    Healthy Participants

    phase 1 small molecule active

    2 trials

  17. NBI-6024

    NEUROCRINE BIOSCIENCES INC

    Type 1 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  18. NBI-77860

    NEUROCRINE BIOSCIENCES INC

    Congenital Adrenal Hyperplasia

    phase 1 small molecule terminated

    1 trial

  19. NBI-98854 50 mg capsule

    NEUROCRINE BIOSCIENCES INC

    Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects

    phase 1 small molecule completed

    1 trial

  20. NBI-98854 50 mg capsule once daily

    NEUROCRINE BIOSCIENCES INC

    Effect of Ketoconazole on the PK of NBI-98854 in Healthy Subjects

    phase 1 small molecule completed

    1 trial

  21. NCO-48 Fumarate

    LIGAND PHARMACEUTICALS INC

    Hepatitis B

    phase 1 small molecule completed

    1 trial

  22. NCO-48 Fumarate 4 mg

    LIGAND PHARMACEUTICALS INC

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  23. ND-003 40mg

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy

    phase 1 small molecule active

    1 trial

  24. NDV-3 vaccine with alum IM

    United Therapeutics Europe Ltd

    Staphylococcal Infections

    phase 1 mab completed

    1 trial

  25. NDX-1017

    BRIGHT MINDS BIOSCIENCES INC.

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  26. NFC-1

    Avalo Therapeutics

    22q11.2 Deletion Syndrome

    phase 1 small molecule completed

    1 trial

  27. NFC-1

    Avalo Therapeutics

    Attention-deficit Hyperactivity Disorder (ADHD)

    phase 1 small molecule completed

    1 trial

  28. NFC-1 100 mg

    Avalo Therapeutics

    Attention Deficit Disorder With Hyperactivity

    phase 1 small molecule completed

    1 trial

  29. NGGT002 Injection

    The First People's Hospital of Lianyungang

    Phenylketonurias

    phase 1 gene therapy active

    1 trial

  30. NK510

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC

    phase 1 small molecule active

    1 trial

  31. NKTR-102

    Nektar Therapeutics UK Limited

    Advanced Cancer

    phase 1 small molecule completed

    1 trial

  32. NKTR-181

    Nektar Therapeutics UK Limited

    Moderate to Severe Chronic Pain

    phase 1 small molecule terminated

    1 trial

  33. NKTR-214

    Nektar Therapeutics UK Limited

    Advanced Cancer

    phase 1 mab completed

    1 trial

  34. NKTR-214 (Cohort A)

    INOVIO PHARMACEUTICALS, INC.

    Metastatic Castration-resistant Prostate Cancer

    phase 1 small molecule completed

    1 trial

  35. NKTR-255

    Nektar Therapeutics UK Limited

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  36. NM1F Injection

    TG THERAPEUTICS, INC.

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  37. NMRA-323511

    Neumora Therapeutics

    Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  38. NNC 0172-0000-2021

    Novo Nordisk A/S

    Congenital Bleeding Disorder

    phase 1 small molecule completed

    1 trial

  39. NNC0480-0389

    Novo Nordisk A/S

    Healthy Volunteers Type 2 Diabetes

    phase 1 small molecule completed

    1 trial

  40. NP-G2-044

    BRIGHT MINDS BIOSCIENCES INC.

    Breast Cancer

    phase 1 small molecule completed

    1 trial

  41. NP101

    Teva Pharma GmbH

    Compare Bioequivalence Patches Previously Used in the NP101-007 Study

    phase 1 small molecule completed

    1 trial

  42. NPC-22

    Belpharma s.a.

    Safety and Pharmacokinetics

    phase 1 small molecule completed

    1 trial

  43. NPC-22

    Belpharma s.a.

    Healthy Adult Subjects

    phase 1 small molecule completed

    1 trial

  44. NRS-033

    BRIGHT MINDS BIOSCIENCES INC.

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  45. NT-301 1 mg

    BRIGHT MINDS BIOSCIENCES INC.

    Tolerability of NT-301 Nasal Spray

    phase 1 other completed

    1 trial

  46. NTQ5082 capsule

    Nanjing Chia-tai Tianqing Pharmaceutical

    Complement-mediated Hemolytic Diseases

    phase 1 small molecule active

    1 trial

  47. NX-1607

    Nurix Therapeutics

    Ovarian Cancer, Epithelial

    phase 1 small molecule active

    1 trial

  48. NX-2127

    Nurix Therapeutics

    Chronic Lymphocytic Leukemia (CLL)

    phase 1 small molecule active

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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