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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 63 of 99

  1. Nivolumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Effect of Drug

    phase 1 small molecule active

    1 trial

  2. Nivolumab

    Iovance Biotherapeutics B.V.

    Melanoma (Skin)

    phase 1 small molecule completed

    1 trial

  3. Nivolumab

    Iovance Biotherapeutics B.V.

    Non-Small Cell Lung Cancer

    phase 1 small molecule completed

    1 trial

  4. Nivolumab

    Bristol-Myers Squibb

    Melanoma

    phase 1 small molecule completed

    1 trial

  5. Nivolumab

    Jazz Pharmaceuticals Ireland Limited

    Small-cell Lung Cancer

    phase 1 small molecule terminated

    1 trial

  6. Nivolumab

    United Therapeutics Europe Ltd

    Ovarian Cancer

    phase 1 small molecule active

    1 trial

  7. Nivolumab

    Atrium Therapeutics

    Brain and Nervous System

    phase 1 small molecule completed

    1 trial

  8. Nizatidine

    ADIAL PHARMACEUTICALS, INC.

    Gastroparesis

    phase 1 small molecule completed

    1 trial

  9. No Intervention

    Takeda

    Rheumatoid Arthritis

    phase 1 other completed

    1 trial

  10. NoV GI.1/GII.4 Bivalent VLP Vaccine

    Takeda

    Gastroenteritis

    phase 1 mab completed

    1 trial

  11. Nomlabofusp

    Larimar Therapeutics

    Friedreich Ataxia

    phase 1 small molecule terminated

    1 trial

  12. Norethindrone/Ethinyl Estradiol

    Teva Pharma GmbH

    Healthy

    phase 1 small molecule completed

    1 trial

  13. Norethindrone/Ethinyl Estradiol

    Teva Pharma GmbH

    Bioequivalence

    phase 1 small molecule completed

    1 trial

  14. Normal Saline (NS) .9% 10 mL Injection

    Blackmores Limited

    Ovarian Failure

    phase 1 small molecule active

    1 trial

  15. Norovirus

    United Therapeutics Europe Ltd

    Healthy Adults

    phase 1 mab completed

    1 trial

  16. Not applicable

    Chiesi Farmaceutici S.p.A

    Non-cystic fibrosis bronchiectasis

    phase 1 other active

    1 trial

  17. Novel Supplement Based Therapy

    Atrium Therapeutics

    Small Intestinal Bacterial Overgrowth

    phase 1 other terminated

    1 trial

  18. Novel restraint

    Lxo Ireland Designated Activity Company

    Acute Respiratory Failure

    phase 1 other completed

    1 trial

  19. OD-07656

    Odyssey Therapeutics

    Inflammatory Bowel Diseases

    phase 1 small molecule completed

    1 trial

  20. ODSH

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 1 small molecule completed

    1 trial

  21. ODSH at 0.125 mg/kg/h

    Jazz Pharmaceuticals Ireland Limited

    Protein Losing Enteropathy

    phase 1 small molecule terminated

    1 trial

  22. OKI-179

    OnKure Therapeutics

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  23. OKI-219

    OnKure Therapeutics

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  24. OKN4395

    Chongqing Precision Biotech Co., Ltd

    Solid Tumours

    phase 1 small molecule active

    1 trial

  25. OMP-131R10

    Mereo BioPharma Group plc

    Advanced Relapsed Tumors

    phase 1 small molecule completed

    1 trial

  26. OMP-18R5

    Mereo BioPharma Group plc

    Solid Tumors

    phase 1 mab completed

    1 trial

  27. OMP-21M18

    Mereo BioPharma Group plc

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  28. OMP-21M18

    Mereo BioPharma Group plc

    Colorectal Cancer

    phase 1 small molecule completed

    1 trial

  29. OMP-305B83

    Mereo BioPharma Group plc

    Advanced Solid Tumor Malignancies

    phase 1 small molecule completed

    1 trial

  30. OMP-305B83

    Mereo BioPharma Group plc

    Cancer Ovaries

    phase 1 small molecule completed

    1 trial

  31. OMP-305B83

    Mereo BioPharma Group plc

    Metastatic Colorectal Cancer

    phase 1 small molecule terminated

    1 trial

  32. OMP-313M32

    Mereo BioPharma Group plc

    Locally Advanced Cancer

    phase 1 small molecule terminated

    1 trial

  33. OMP-336B11

    Mereo BioPharma Group plc

    Locally Advanced Malignant Neoplasm

    phase 1 small molecule terminated

    1 trial

  34. OMP-52M51

    Mereo BioPharma Group plc

    Relapsed or Refractory Lymphoid Malignancies

    phase 1 small molecule completed

    1 trial

  35. OMP-52M51

    Mereo BioPharma Group plc

    Relapsed or Refractory Solid Tumors

    phase 1 small molecule completed

    1 trial

  36. OMP-54F28

    Mereo BioPharma Group plc

    Solid Tumors

    phase 1 mab completed

    1 trial

  37. OMP-54F28 with Sorafenib

    Mereo BioPharma Group plc

    Hepatocellular Cancer

    phase 1 small molecule completed

    1 trial

  38. OMP-54F28, Nab-Paclitaxel and Gemcitabine

    Mereo BioPharma Group plc

    Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  39. OMP-54F28, Paclitaxel and Carboplatin

    Mereo BioPharma Group plc

    Ovarian Cancer

    phase 1 small molecule completed

    1 trial

  40. OMP-59R5

    Mereo BioPharma Group plc

    Solid Tumors

    phase 1 small molecule completed

    1 trial

  41. OMTX705-006 Phase 1b

    Lacuna Pharma Pty Ltd

    Advanced/Metastatic Pancreatic Adenocarcinoma

    phase 1 other active

    1 trial

  42. ONC206

    Jazz Pharmaceuticals Ireland Limited

    Diffuse Midline Glioma (DMG)

    phase 1 small molecule active

    1 trial

  43. ONC206

    Jazz Pharmaceuticals Ireland Limited

    Central Nervous System Neoplasms

    phase 1 small molecule active

    1 trial

  44. ONC206 Powder

    AXIM BIOTECHNOLOGIES, INC.

    Diffuse Midline Glioma (DMG), and Other Recurrent Primary Malignant Central Nervous System (CNS) Tumors

    phase 1 small molecule active

    1 trial

  45. ONO-4578

    Ono Pharmaceutical Co.,

    Metastatic Pancreatic Cancer

    phase 1 small molecule completed

    1 trial

  46. ONX-0801

    United Therapeutics Europe Ltd

    Solid Tumours

    phase 1 small molecule completed

    1 trial

  47. OP-3136

    Olema Pharmaceuticals

    Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)

    phase 1 small molecule active

    1 trial

  48. OPB-31121

    Otsuka Beijing Research Institute

    Non-Hodgkin's Lymphoma(NHL)

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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