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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

Page 19 of 99

  1. ARCT-2304

    Arcturus Therapeutics Holdings

    Influenza, Human

    phase 1 mab completed

    1 trial

  2. ARISE with AR

    BRIGHT MINDS BIOSCIENCES INC.

    Pediatric Cancer

    phase 1 other active

    1 trial

  3. ARN-75039 oral capsules

    United Therapeutics Europe Ltd

    Healthy Adult Participants

    phase 1 small molecule completed

    1 trial

  4. ARO-AAT Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Alpha 1-Antitrypsin Deficiency

    phase 1 small molecule completed

    1 trial

  5. ARO-ANG3

    Arrowhead Pharmaceuticals Ireland Limited

    Dyslipidemias

    phase 1 small molecule completed

    1 trial

  6. ARO-APOC3

    Arrowhead Pharmaceuticals Ireland Limited

    Hypertriglyceridemia

    phase 1 small molecule completed

    1 trial

  7. ARO-ATXN2 Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Spinocerebellar Ataxia Type 2

    phase 1 small molecule active

    1 trial

  8. ARO-CFB

    Arrowhead Pharmaceuticals Ireland Limited

    IgA Nephropathy

    phase 1 small molecule completed

    1 trial

  9. ARO-HIF2

    Arrowhead Pharmaceuticals Ireland Limited

    Clear Cell Renal Cell Carcinoma

    phase 1 small molecule completed

    1 trial

  10. ARO-RAGE Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Asthma

    phase 1 small molecule completed

    1 trial

  11. ARO-SOD1 Injection

    Arrowhead Pharmaceuticals Ireland Limited

    Amyotrophic Lateral Sclerosis

    phase 1 small molecule terminated

    1 trial

  12. ARQ 197

    KYOWA KIRIN AUSTRALIA PTY LTD

    Advanced Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  13. ARQ-151 cream 0.15%

    Arcutis Biotherapeutics

    Atopic Dermatitis (Eczema)

    phase 1 small molecule completed

    1 trial

  14. ARQ-151- cream 0.3%

    Arcutis Biotherapeutics

    Plaque Psoriasis

    phase 1 small molecule completed

    1 trial

  15. ARQ-154 Foam 0.3%

    Arcutis Biotherapeutics

    Psoriasis

    phase 1 small molecule completed

    1 trial

  16. ARQ-234

    Arcutis Biotherapeutics

    Atopic Dermatitis (AD)

    phase 1 mab active

    1 trial

  17. ARS-1 with URTI

    Ars Pharmaceuticals Irl Limited

    Upper Respiratory Tract Infection

    phase 1 small molecule completed

    1 trial

  18. ART-I02

    BRIGHT MINDS BIOSCIENCES INC.

    Arthritis, Rheumatoid

    phase 1 gene therapy active

    1 trial

  19. ASC30

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Weight Management

    phase 1 small molecule completed

    1 trial

  20. ASC47

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Weight Management

    phase 1 small molecule completed

    1 trial

  21. ASP1941

    Astellas Pharma Inc

    Healthy

    phase 1 small molecule completed

    1 trial

  22. ASP8062

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  23. ASP8082

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 1 small molecule completed

    1 trial

  24. ASP8374

    Regeneron UK Limited

    Glioblastoma

    phase 1 small molecule completed

    1 trial

  25. ASTX660

    United Therapeutics Europe Ltd

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  26. ASTX727, ASTX727, Decitabine, ASTX727

    Taiho Pharma Netherlands B.V.

    Myelodysplastic Syndromes (MDS)

    phase 1 small molecule active

    1 trial

  27. AT-301B

    ATOSSA THERAPEUTICS, INC.

    Healthy

    phase 1 small molecule completed

    1 trial

  28. AT-527

    Atea Pharmaceuticals

    Chronic Hepatitis C

    phase 1 small molecule completed

    1 trial

  29. AT-527

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  30. AT-527

    Atea Pharmaceuticals

    Healthy Volunteer

    phase 1 small molecule completed

    1 trial

  31. AT-527 (R07496998)

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  32. AT-527 + digoxin

    Atea Pharmaceuticals

    Healthy Volunteers Study

    phase 1 small molecule completed

    1 trial

  33. AT-527 550 mg + cyclosporine

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  34. AT-527 550 mg + midazolam

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  35. AT-527 Formulation 1

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  36. AT-527 fasted

    Atea Pharmaceuticals

    Healthy Volunteer Study

    phase 1 small molecule completed

    1 trial

  37. AT-752

    Atea Pharmaceuticals

    Dengue

    phase 1 small molecule completed

    2 trials

  38. ATA3219

    Evidence Based Cataract Study Group

    Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

    phase 1 small molecule terminated

    1 trial

  39. ATA3219

    Evidence Based Cataract Study Group

    Lupus Nephritis

    phase 1 small molecule terminated

    1 trial

  40. ATAFENOVIR 200 MG KAPSUL

    BRIGHT MINDS BIOSCIENCES INC.

    Bioequivalence

    phase 1 small molecule active

    1 trial

  41. ATG-010 and ATG-008

    Shanghai Antengene Corporation Limited

    Relapsed/Refractory Diffuse Large B-cell Lymphoma

    phase 1 other terminated

    1 trial

  42. ATHENA CAR-T

    The First People's Hospital of Lianyungang

    Lupus Erythematosus, Systemic

    phase 1 mab active

    1 trial

  43. ATI-1013 (0.2 g)

    BRIGHT MINDS BIOSCIENCES INC.

    Thromboangiitis Obliterans (Buerger's Disease)

    phase 1 mab active

    1 trial

  44. ATI-2231

    Aclaris Therapeutics

    Advanced Solid Tumor

    phase 1 small molecule terminated

    1 trial

  45. ATRA

    United Therapeutics Europe Ltd

    Pancreatic Adenocarcinoma

    phase 1 small molecule completed

    1 trial

  46. AU-011

    Aura Biosciences

    Non-muscle-invasive Bladder Cancer

    phase 1 small molecule active

    1 trial

  47. AV-101

    Vistagen Therapeutics

    Drug Drug Interaction

    phase 1 small molecule active

    1 trial

  48. AV-101

    BRIGHT MINDS BIOSCIENCES INC.

    Neuropathic Pain

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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