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Intelligence · Clinical Pipeline

Phase I Pipeline Programs

First-in-human and early clinical safety studies in Phase I.

Programs
4,713

Quick answer

NovaPharmaNews tracks 4,713 phase i pharmaceutical pipeline programs from ClinicalTrials.gov. First-in-human and early clinical safety studies in Phase I.

Top sponsors

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  1. A two-part trial in healthy volunteers to find out how long JNJ-77242113 stays in and acts on the body when administered as different tablet formulations and under different food and water conditions, and to assess the acceptability profile (taste, palatability, and smell) of JNJ-77242113 formulations.

    Janssen-Cilag International N.V.

    Inflammatory Conditions

    phase 1 other active

    1 trial

  2. A-CAR028

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia (AML)

    phase 1 mab active

    1 trial

  3. AAV8-hCocH

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence, in Remission

    phase 1 small molecule active

    1 trial

  4. AB-101

    Artiva Biotherapeutics

    Rheumatoid Arthritis

    phase 1 small molecule active

    1 trial

  5. AB-101

    Arbutus Biopharma Corp

    Chronic Hepatitis b

    phase 1 small molecule completed

    1 trial

  6. AB-101

    Artiva Biotherapeutics

    Lupus Nephritis - WHO Class III

    phase 1 small molecule active

    1 trial

  7. AB-836

    Arbutus Biopharma Corp

    Chronic Hepatitis

    phase 1 small molecule terminated

    1 trial

  8. AB-SA01 (10^8 PFU per phage)

    Armata Pharmaceuticals

    Healthy Volunteers

    phase 1 mab completed

    1 trial

  9. AB308

    Arcus Biosciences

    Advanced Solid Tumor

    phase 1 small molecule completed

    1 trial

  10. AB598

    Arcus Biosciences

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  11. AB680

    Arcus Biosciences

    Healthy Volunteers

    phase 1 small molecule completed

    2 trials

  12. AB680

    Arcus Biosciences

    Advanced Pancreatic Cancer

    phase 1 small molecule active

    1 trial

  13. AB801

    Arcus Biosciences

    Cancer

    phase 1 small molecule completed

    1 trial

  14. AB801

    Arcus Biosciences

    Advanced Cancer

    phase 1 small molecule active

    1 trial

  15. ABI-1179

    ASSEMBLY BIOSCIENCES, INC.

    Recurrent Genital Herpes Simplex Type 2

    phase 1 small molecule completed

    1 trial

  16. ABI-4334

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  17. ABI-4334 Tablet

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  18. ABI-5366

    ASSEMBLY BIOSCIENCES, INC.

    Recurrent Genital Herpes Simplex Type 2

    phase 1 small molecule completed

    1 trial

  19. ABI-6250

    ASSEMBLY BIOSCIENCES, INC.

    Hepatitis Delta Virus

    phase 1 small molecule completed

    1 trial

  20. ABI-H2158

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    3 trials

  21. ABI-H2158 Reference Formulation

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  22. ABI-H3733

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  23. ABI-H3733 Liquid Oral Dosage Form

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 1 small molecule completed

    1 trial

  24. ABI-M201

    ASSEMBLY BIOSCIENCES, INC.

    Ulcerative Colitis Chronic Mild

    phase 1 small molecule terminated

    1 trial

  25. ABT-493

    AbbVie

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

  26. ACR-2316

    Acrivon Therapeutics

    Specific Advanced Solid Tumors

    phase 1 small molecule active

    1 trial

  27. ACTINIUM-225-LABELED HUMANIZED ANTI-CD33 MONOCLONAL ANTIBODY HuM195

    Actinium Pharmaceuticals

    Leukemia

    phase 1 mab completed

    1 trial

  28. ACTOS (Pioglitazone)

    Takeda

    Multiple Sclerosis, Relapsing-Remitting

    phase 1 small molecule completed

    1 trial

  29. ACTR T Cell Product

    Cogent Biosciences

    Solid Tumor

    phase 1 mab terminated

    1 trial

  30. ACTR087

    Cogent Biosciences

    Lymphoma

    phase 1 mab completed

    1 trial

  31. ACTR087

    Cogent Biosciences

    Multiple Myeloma

    phase 1 mab terminated

    1 trial

  32. ACTR707

    Cogent Biosciences

    Lymphoma

    phase 1 mab terminated

    1 trial

  33. ACU193

    Acumen Pharmaceuticals

    Alzheimer Disease

    phase 1 small molecule completed

    1 trial

  34. ADASUVE®

    Teva Pharma GmbH

    BiPolar

    phase 1 small molecule completed

    1 trial

  35. ADCLEC.syn1 CAR T cells

    Takeda

    Acute Myeloid Leukemia

    phase 1 mab active

    1 trial

  36. ADCT-301

    ADC Therapeutics SA

    Acute Myeloid Leukemia

    phase 1 small molecule terminated

    1 trial

  37. ADCT-301

    ADC Therapeutics SA

    Head and Neck Cancer Squamous Cell Carcinoma

    phase 1 small molecule terminated

    1 trial

  38. ADCT-402

    ADC Therapeutics SA

    Non-Hodgkin Lymphoma

    phase 1 small molecule completed

    1 trial

  39. ADCT-402

    ADC Therapeutics SA

    Acute Lymphoblastic Leukemia

    phase 1 small molecule terminated

    1 trial

  40. ADCT-502

    ADC Therapeutics SA

    Breast Cancer

    phase 1 small molecule terminated

    1 trial

  41. ADCT-601

    ADC Therapeutics SA

    Advanced Solid Tumors

    phase 1 small molecule terminated

    2 trials

  42. ADCT-901

    ADC Therapeutics SA

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  43. ADME: A Study to Understand What the Body does to the Study Compound Called PF-07220060 When Taken by Healthy Adults.

    Pfizer Australia Pty Ltd

    metastatic/advanced breast cancer

    phase 1 other active

    1 trial

  44. ADX48621

    Addex Therapeutics

    Healthy

    phase 1 small molecule completed

    1 trial

  45. AEVI-007

    Avalo Therapeutics

    Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  46. AFN50 injection

    The First People's Hospital of Lianyungang

    Autoimmune Diseases

    phase 1 mab active

    1 trial

  47. AFQ056

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 1 small molecule terminated

    1 trial

  48. AG-120 (Ivosidenib)

    Agios Netherlands B.V.

    Hepatic Impairment

    phase 1 small molecule completed

    1 trial

Frequently asked questions

How many Phase I pipeline programs are in the directory?

4,713 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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