Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11602559

    HIV-1 Env fusion peptide immunogens and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11603392

    Vault particles having a modified R8 flexible region

    The Regents of the University of California · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11603542

    Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

    VOYAGER THERAPEUTICS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11602567

    Methods for modulating RNA splicing

    PTC THERAPEUTICS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11602563

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11602551

    Use of inosine for the treatment of t-reg deficiency

    The Board of Regents of the University of Texas System · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11602515

    Pharmaceutical compositions comprising dimethyl fumarate

    Almirall, S.A. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11602556

    Insulin mimotopes and methods of using the same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11602568

    Engineered B lymphocytes and compositions having micro-RNA and methods for making and using them

    The Regents of the University of California · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11603519

    T-cell receptor

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11603413

    Anti-TMPRSS2 antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11603412

    Antibodies against CDCP1 for the treatment and detection of cancer

    The Regents of the University of California · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11603408

    Methods for treating skin infection by administering an IL-4R antagonist

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11603407

    Stable antibody formulation

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11603376

    Compositions and methods for treating cancer

    The Regents of the University of California · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11603364

    Acyl hydrazone derivative compounds for treating disease

    Alterity Therapeutics Limited · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11603406

    Antibodies binding to VISTA at acidic pH

    Five Prime Therapeutics, Inc. · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11603351

    Carboxamides as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11603365

    Salt forms and polymorphs of (r)-1-(4-(6-(2-(4-(3,3-difluorocyclobutoxy)-6-methylpyridin-2-yl)acetamido) pyridazin-3-yl)-2-fluorobutyl)-n-methyl-1H-1,2,3-triazole-4-carboxamide

    The Board of Regents of the University of Texas System · Granted Tue Mar 14 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 09 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11608275

    Method for producing zinc oxide platelets with controlled size and morphology

    ENTEKNO ENDUSTRIYEL TEKNOLOJIK VE NANO MALZEMELER SANAYIVE TICARET ANONIM SIRKETI · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11607557

    Devices and systems for treating pain based on light therapy

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11608454

    High performance adhesives; methods of making; and use

    South China University of Technology · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11607427

    Method for chemoselection

    The Regents of the University of California · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11607426

    Method of targeting oncolytic viruses to tumors

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11607462

    Systems and methods for minimally-invasive assessment of toxicity-induced tissue injury

    Northwestern University · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11607448

    Whole avian-origin reverse genetic system and its use in producing H7N9 subtype avian influenza vaccine

    SOUTH CHINA AGRICULTURAL UNIVERSITY · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11607456

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11608354

    Prodrugs of a JAK inhibitor compound for treatment of gastrointestinal inflammatory disease

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11607450

    Smallpox vaccine for cancer treatment

    Calidi Biotherapeutics, Inc. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11607412

    Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF)

    TENAX THERAPEUTICS, INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11607370

    Dental composition

    KURARAY NORITAKE DENTAL INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11607407

    Dermal pharmaceutical compositions of 1-methyl-2′,6′-pipecoloxylidide and method of use

    Relmada Therapeutics, Inc. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11607435

    Probiotics Bifidobacteria strains

    PERFECT (CHINA) CO., LTD. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11608492

    Compositions for linking DNA-binding domains and cleavage domains

    Sangamo Therapeutics, Inc. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11607387

    Efficient aqueous encapsulation and controlled release of bioactive agents

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11607414

    Small molecule inhibitors of EGFR and PI3K

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11608503

    RNA targeting of mutations via suppressor tRNAs and deaminases

    The Regents of the University of California · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11607464

    Compositions and methods for the treatment and imaging of cancer

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11608489

    Compositions and methods for performing magnetibuoyant separations

    BioLegend, Inc. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11607408

    Method of treatment of schizophrenia

    VANDA PHARMACEUTICALS INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11608378

    Antibodies that bind integrin AVB8 and uses thereof

    The Regents of the University of California · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11610666

    Systems and methods of managing treatment of a chronic condition by symptom tracking

    Corcept Therapeutics Incorporated · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11608335

    Somatostatin modulators and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11608367

    Peptides for angiogenic therapy

    The Regents of the University of California · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11608346

    Ras inhibitors

    Revolution Medicines, Inc. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11608381

    Methods of treatment using a leptin receptor agonist antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11608308

    Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same

    The Regents of the University of California · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11608501

    Methods for modifying RNA splicing

    PTC THERAPEUTICS, INC. · Granted Tue Mar 21 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 16 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.