Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11857531

    Combination mast cell inhibition for treatment of BPH/LUTS

    Northwestern University · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11858884

    Compositions and methods for modulating gene or gene product in cells

    The Board of Regents of the University of Texas System · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11857524

    Stable oral suspensions of baclofen

    ANI Pharmaceuticals, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11857574

    Genetically engineered T cells with Regnase-1 and/or TGFBRII disruption have improved functionality and persistence

    CRISPR THERAPEUTICS AG · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11857641

    Method for the treatment of mucopolysaccharidosis type I

    Sangamo Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11857651

    Compositions with doped titanium dioxide nanoparticles and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11857535

    Methods of treating mutant lymphomas

    Kymera Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11857697

    Compositions and methods for obtaining 3-dimensional lung-like epithelium and related uses thereof

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11857613

    Vaccine for prevention of necrotic enteritis in poultry

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11858915

    Polo like kinase 4 inhibitors

    ORIC PHARMACEUTICALS, INC. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11859010

    Antibodies, activatable antibodies, bispecific antibodies, and bispecific activatable antibodies and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11858910

    Pyridinylmethylenepiperidine derivatives and uses thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11858953

    Compositions and methods for synthesis of phosphorylated molecules

    The Regents of the University of California · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11858970

    Chili pepper seed isolated oligopeptide FTLE and application thereof in preventing or treating cancer

    China Agricultural University · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11859007

    Humanized anti-CD73 antibodies

    Corvus Pharmaceuticals, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11859000

    Anti-CCR8 antibodies and uses thereof

    VACCINEX, INC. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11858957

    Ectonucleotidase inhibitors and methods of use thereof

    ANTENGENE THERAPEUTICS LIMITED · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11858931

    Amino acid compounds with unbranched linkers and methods of use

    Pliant Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11858932

    Methods and compositions for treating polycystic ovary syndrome

    SPRUCE BIOSCIENCES, INC. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11858895

    Aminated psilocybin derivatives and methods of using

    Enveric Biosciences Canada Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11857608

    Dosage forms of tissue kallikrein 1

    DiaMedica Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11858941

    Heterocyclic and heteroaryl compounds for treating Huntington's disease

    PTC THERAPEUTICS, INC. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11857647

    Pharmaceutical composition comprising tetrofosmin and pharmaceutically acceptable salts thereof

    Jubilant Draximage Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11857550

    Benzathine analogs

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11857528

    Methods of providing solriamfetol therapy to subjects with impaired renal function

    AXSOME MALTA LTD. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11859190

    Methods and compositions for regulation of transgene expression

    Sangamo Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11859180

    Antisense oligonucleotide compositions

    Ionis Pharmaceuticals, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11859016

    Peptide having cytoprotective effect against environmental pollutant and use thereof

    CAREGEN CO., LTD. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11859021

    Compounds for regulating trained immunity, and their methods of use

    Trained Therapeutix Discovery, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11859185

    Glucokinase (GCK) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11859234

    Method of monitoring RNase L activity

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11858930

    Fused bicyclic RAF inhibitors and methods for use thereof

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11858913

    Bicyclic pyridazinones and methods of use thereof

    Aligos Therapeutics, Inc. · Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. IT 202200013882

    PRODOTTO DI FERMENTAZIONE PER IL TRATTAMENTO DI MALATTIE INFIAMMATORIE.

    ALFASIGMA SPA [IT] · Granted Thu Jan 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. CA 3260357

    RÉGIME DE PRIMO-IMMUNISATION DE VIRUS DE LA VACCINE ANKARA (MVA) ET DE PETIT ARN ACTIVATEUR (VRP) MODIFIÉS RECOMBINANTS

    BAVARIAN NORDIC AS [DK] · Granted Thu Jan 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. CA 3259886

    DISPOSITIFS DE DÉPLACEMENT D'IGE-FCERI

    UNIV AARHUS [DK] · Granted Thu Jan 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. CA 3258751

    LIGNÉE CELLULAIRE DE MAMMIFÈRE POUR LA PRODUCTION DE VIRUS DE LA VACCINE ANKARA MODIFIÉ (MVA)

    BAVARIAN NORDIC AS [DK] · Granted Thu Jan 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. CA 3260379

    VACCIN CONTRE LE VIRUS D'EPSTEIN-BARR

    BAVARIAN NORDIC AS [DK] · Granted Thu Jan 04 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Dec 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.