Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11679131

    Genetically engineered T cells with regnase-1 and/or TGFBRII disruption have improved functionality and persistence

    CRISPR THERAPEUTICS AG · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11679128

    Methods of producing enriched populations of tumor reactive T cells from peripheral blood

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11679119

    Bortezomib compositions

    MAIA PHARMACEUTICALS, INC. · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11679109

    SMARCA degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11679113

    Anticancer treatment for uveal melanoma

    The Regents of the University of California · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11679112

    Cancer treatments using combinations of CDK and ERK inhibitors

    Biomed Valley Discoveries, Inc. · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11679103

    Multi-targeting agents for Alzheimer's disease therapy

    The Regents of the University of California · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11679079

    Ophthalmic formulations and related methods

    ETERNATEAR, INC. · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11679078

    Ophthalmic formulations and related methods

    ETERNATEAR, INC. · Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. CA 3242445

    POLYPEPTIDES COMPRENANT DES DOMAINES VARIABLES UNIQUES D'IMMUNOGLOBULINE CIBLANT TCRAS, CD33 ET CD123

    ABLYNX NV [BE] · Granted Thu Jun 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11686735

    Systems and methods to identify and treat subjects at risk for obstetrical complications

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11685909

    CRISPR-Cas effector polypeptides and methods of use thereof

    The Regents of the University of California · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11684657

    HLA-restricted VGLL1 peptides and use thereof in promoting an immune response in a subject

    The Board of Regents of the University of Texas System · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11684609

    Compounds and methods for treating an epileptic disorder

    The Regents of the University of California · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11684596

    Antidiabetic pharmaceutical compositions and preparation method thereof

    Elite Pharmaceutical Solution Inc. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11684597

    Administration of tailored feedstock to increase nitro-containing amphenicol antibiotic susceptibility

    The United States of America as represented by the Secretary of the Army · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11684050

    Non-human animals having a humanized programmed cell death 1 gene

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11685744

    CDK inhibitors and their use as pharmaceuticals

    Prelude Therapeutics, Incorporated · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11685775

    Method of increasing the ratio of effector T cells to regulatory T cells in a tumor by administering to a subject a TGF-beta inhibitor and a PD-1 antibody

    The Regents of the University of California · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11685780

    Single domain antigen binding domains that bind human Trop2

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11685710

    Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

    The Board of Regents of the University of Texas System · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11685921

    Molecules and agents for treating hepatitis B virus

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11685918

    Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11685906

    Compositions and methods for treating ornithine transcarbamylase deficiency

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11685784

    Anti-immune-checkpoint nanobody and nucleic acid encoding sequence thereof, and uses of the same

    China Medical University Hospital · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11685750

    Crystalline forms of IRAK degraders

    Kymera Therapeutics, Inc. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11685721

    Human plasma kallikrein inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11685746

    Heteroaryl compounds for treating Huntington's disease

    PTC THERAPEUTICS, INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11685771

    Recombinant factor VIII proteins

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11685749

    C26-linked rapamycin analogs as mTOR inhibitors

    Revolution Medicines, Inc. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11684632

    Maribavir isomers, compositions, methods of making and methods of using

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11684761

    Preparation comprising exanatide for delivery into a lumen of the intestinal tract

    Rani Therapeutics, LLC · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11684797

    Laser assisted wound healing protocol and system

    THE BIOREGENTECH INSTITUTE, INC. · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11684612

    Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator

    Corcept Therapeutics Incorporated · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11684600

    Composition of active agents to positively affect a robust mammalian endocannabinoid system tone to better address age related discomfort

    COMPACT DISC INCORPORATED · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11684614

    Formulations of hydroxypyridonate actinide/lanthanide decorporation agents

    The Regents of the University of California · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11684572

    Methods for producing carboxylate ligand modified ferric iron hydroxide colloids and related compositions and uses

    United Kingdom Research and Innovation · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11684585

    Nanoscale coatings for encapsulation of biological entities

    The Regents of the University of California · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11684570

    Pharmaceutical ophthalmic compositions

    EYE CARE NORTHWEST, PA · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11684626

    Methods and compositions comprising ursolic acid and/or resveratrol for treating obesity, diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11684638

    Targeted delivery system, system components, and methods

    Regents of the University of Minnesota · Granted Tue Jun 27 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 22 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 2023203129

    ANTI-HER2 POLYPEPTIDES DERIVATIVES AS NEW DIAGNOSTIC MOLECULAR PROBES

    BRACCO IMAGING SPA [IT] · Granted Thu Jun 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. WO 2023118563

    THÉRAPIE POUR MODULER UNE RÉPONSE IMMUNITAIRE AU MOYEN D'UN MVA RECOMBINANT CODANT POUR IL-12

    BAVARIAN NORDIC AS [DK] · Granted Thu Jun 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. WO 2023118508

    VIRUS MVA RECOMBINANTS POUR ADMINISTRATION INTRAPÉRITONÉALE POUR LE TRAITEMENT DU CANCER

    BAVARIAN NORDIC AS [DK] · Granted Thu Jun 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11691972

    Compounds for targeted degradation of BRD9

    C4 THERAPEUTICS, INC. · Granted Tue Jul 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11691992

    Oxaborole analogs and uses thereof

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Jul 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11691948

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue Jul 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11690895

    Compositions and methods of interferon alpha binding proteins

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jul 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.