Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11260120

    Immunogenic composition comprising a fusion peptide derived from superantigen toxoids

    INTEGRATED BIOTHERAPEUTIC VACCINES, INC. · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11260092

    Fungal immunogens and related materials and methods

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11260050

    Combination of cotinine plus antioxidant for treatment-resistant depression and correction of astrocytes functional deficit induced by depression and other neuropathological

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11261447

    Methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression

    Alnylam Pharmaceuticals, Inc. · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11261437

    Procoagulant compounds

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11260058

    Compositions and method of treating cancer

    The Regents of the University of California · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11260185

    Pressurized metered dose inhalers and method of manufacture

    Cardiff Scintigraphics Limited · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11260083

    Compositions and methods for treating and preventing graft versus host disease

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11261197

    Neprilysin inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Mar 01 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 24 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 2022062444

    PHARMACEUTICAL COMPOSITIONS COMPRISING GD-COMPLEXES AND POLYARYLENE ADDITIVES

    BRACCO IMAGING SPA [IT] · Granted Thu Mar 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. WO 2022043557

    MÉTHODE DE TRAITEMENT DE CANCERS EXPRIMANT LE PSMA

    ADVANCED ACCELERATOR APPLICATIONS INT SA [CH] · Granted Thu Mar 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. WO 2022043558

    MÉTHODE DE TRAITEMENT DE CANCERS EXPRIMANT LE PSMA

    ADVANCED ACCELERATOR APPLICATIONS INT SA [CH] · Granted Thu Mar 03 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11267822

    BET bromodomain protein degraders with cleavable linkers

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11267785

    Process for preparing [(3-hydroxypyridine-2-carbonyl)amino]alkanoic acids, esters and amides

    Akebia Therapeutics, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11266742

    Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates

    Nektar Therapeutics · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11266724

    Modified factor VII polypeptides for subcutaneous administration and on-demand treatment

    Catalyst Biosciences, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11266720

    Factor VIII-FC chimeric and hybrid polypeptides, and methods of use thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11266693

    Nucleic acids encoding engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11266699

    Synergistic bacterial compositions and methods of production and use thereof

    Seres Therapeutics, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11266676

    MicroRNA in T cell activation

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11266661

    Vaginal inserted estradiol pharmaceutical compositions and methods

    Compass Therapeutics LLC · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11266657

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11266655

    Methods and compositions for treating urea cycle disorders

    CAMP4 Therapeutics Corporation · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11266641

    Formulations of a somatostatin modulator

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11266488

    Tissue repair fiber membrane, preparation method and application thereof, and tissue repair product

    Medprin Regenerative Medical Technologies Co., Ltd. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11266611

    More potent and less toxic formulations of epinephrine and methods of medical use

    Eton Pharmaceuticals, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11268154

    Methods for the identification, evaluation and treatment of patients having multiple myeloma

    Takeda Pharmaceutical Company Limited · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11267893

    Anti-IL36R antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11266726

    Compositions and methods for the treatment of HER2-expressing solid tumors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11267832

    Mn(II)-based sensors to detect zinc in vivo with MRI

    The Board of Regents of the University of Texas System · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11266649

    Pharmaceutical formulations

    Corvus Pharmaceuticals, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11266692

    Intracellular genomic transplant and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11266622

    Method of treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11266694

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11268098

    Non-aggregating immunostimulatory oligonucleotides

    GeneDesign, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11268145

    Methods for treating Cushing's syndrome

    Corcept Therapeutics Incorporated · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11268096

    Compounds for modulating Fc-epsilon-RI-beta expression and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11268065

    Genetically-modified cells comprising a modified human T cell receptor alpha constant region gene

    Precision BioSciences, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11267896

    Anti-CD71 antibodies, activatable anti-CD71 antibodies, and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11267859

    GM-CSF mimetics and methods of making and using same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11267845

    Inhibitors of CD73-mediated immunosuppression

    Arcus Biosciences, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11267812

    KRAS G12C inhibitors

    Mirati Therapeutics, Inc. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11267782

    Tetrahydro-1H-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2α inhibitors

    NIKANG THERAPEUTICS, INC. · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11266746

    Therapeutic antitumor combination of a TLR4 ligand with other treatments

    The United Slates of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11268077

    Materials and methods for treatment of hemoglobinopathies

    Vertex Pharmaceuticals Incorporated · Granted Tue Mar 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 03 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. EP 3964220

    PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR BEHANDLUNG VON OSTEOPOROSE

    BIOCODEX [FR] · Granted Wed Mar 09 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Mar 04 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 2022072166

    METHOD OF TREATMENT OF NEUROENDOCRINE TUMORS

    ADVANCED ACCELERATOR APPLICATIONS S A [FR] · Granted Thu Mar 10 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Mar 05 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11275080

    Methods for stratifying non-responders to therapies that block PD1/PDL1 axis

    The Regents of the University of California · Granted Tue Mar 15 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Mar 10 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.